Hydroquinone is a topical prescription drug that is used to treat skin conditions that cause hyperpigmentation (darkened skin), such as melasma. Hydroquinone is used for its skin-lightening effects. Hydroquinone is available by prescription only. The average cost of Hydroquinone without insurance is $123.48 per 1, 28.35gm of 4% tube. You can use a free coupon from SingleCare to save money on your Hydroquinone prescription. Our lowest price for [generic] Hydroquinone is $21.99 for 1, 28.35gm of 4% tube.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 12/05/2025
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Hydroquinone is a topical prescription drug that is used to treat skin conditions that cause hyperpigmentation (darkened skin), such as melasma. Hydroquinone is used for its skin-lightening effects. Hydroquinone is available by prescription only. The average cost of Hydroquinone without insurance is $123.48 per 1, 28.35gm of 4% tube. You can use a free coupon from SingleCare to save money on your Hydroquinone prescription. Our lowest price for [generic] Hydroquinone is $21.99 for 1, 28.35gm of 4% tube.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Hydroquinone Retail Price | Hydroquinone SingleCare Price |
|---|---|---|
| CVS Pharmacy | $30.90 | $30.62 |
| Walmart | $75.85 | $31.52 |
| Walgreens | $85.05 | $46.42 |
| Kroger Pharmacy | $110.87 | $24.95 |
| Albertsons Pharmacy | $90.27 | $30.11 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Hydroquinone is a topical prescription drug that is used to treat skin conditions that cause hyperpigmentation (darkened skin), such as melasma. Hydroquinone is used for its skin-lightening effects. Hydroquinone is available by prescription only. The average cost of Hydroquinone without insurance is $123.48 per 1, 28.35gm of 4% tube. You can use a free coupon from SingleCare to save money on your Hydroquinone prescription. Our lowest price for [generic] Hydroquinone is $21.99 for 1, 28.35gm of 4% tube.
The generic of Hydroquinone costs $21.99 for 1, 28.35gm of 4% tube with a free Hydroquinone coupon from SingleCare. You could reduce this cost more depending on your prescription details. Use the dropdown menu above to enter your prescription details (i.e., generic/brand, quantity, dosage, form) to see the most accurate prices of Hydroquinone with SingleCare near you.
The retail price of Hydroquinone without insurance is about $123.48 per 1, 28.35gm of 4% tube. This medicine is generic, and by using a SingleCare savings card or coupon, you can pay a discounted price of $21.99 for this prescription medication.
Insurance coverage for Hydroquinone varies. Because Hydroquinone is often considered a cosmetic drug, not all insurances will cover it. If your plan does cover Hydroquinone, your price will depend on your specific plan and deductible. You can contact your insurance plan for more information about Hydroquinone coverage and your out-of-pocket costs.
Medicare prescription plans do not typically cover Hydroquinone, although there may be some exceptions. To find out if your Medicare prescription plan covers Hydroquinone, you can check the formulary (list of covered drugs and their pricing tiers) or contact your specific plan’s member services department. If Hydroquinone is covered on your plan, the price will depend on your deductible and coverage state. However, if your Medicare prescription plan does not provide coverage for Hydroquinone—or if your price with Medicare is still expensive—you can use a free SingleCare discount to pay for your Hydroquinone prescription instead. Without insurance, Hydroquinone costs an average of $123 for one, 28.35 gram tube. However, by using a SingleCare discount, you can pay a lower price of $21.99 for your Hydroquinone prescription.
Medicaid coverage varies by state. Your plan may or may not cover Hydroquinone. If your Medicaid plan does not cover Hydroquinone or if your cost with Medicaid is still high, you can use the SingleCare discount instead. SingleCare is a discount program—it is not insurance. You can use SingleCare to pay as low as $21.99 for 1, 28.35gm of 4% tube.
Hydroquinone is a generic drug and it is made by several generic manufacturers, such as Westminster Pharmaceuticals, Acella Pharmaceuticals, and others. Brand-name versions of Hydroquinone are not common and may not be available. You can use a SingleCare coupon to pay as low as $21.99 for 1, 28.35gm of 4% tube.
The most reliable way to save on your Hydroquinone prescription is by using a SingleCare discount. SingleCare is free and easy to use, and is accepted at over 35,000 pharmacies in the United States and Puerto Rico. Because SingleCare is not an insurance program, you can use it in place of insurance, as a discount card. You can also find out if you are eligible for Medicare Part D Extra Help. And you can usually use your HSA or FSA card to pay for your prescription.
Tri-Luma is a drug that contains Hydroquinone as one of three active ingredients (in addition to tretinoin and fluocinolone), but it is not cheaper than Hydroquinone alone. There are no less expensive alternatives that are very similar to Hydroquinone. However, your healthcare professional can give you medical advice on other drugs that may help your condition. Some healthcare professionals prescribe Azelex (azelaic acid) off-label (for a non-FDA-approved use) for certain skin conditions such as melasma.
You can use SingleCare coupons at most major pharmacies and grocers, such as Walgreens, Kroger, Walmart, CVS, Safeway, and more. Simply text, email, print, or save your free Hydroquinone coupon to your digital wallet and show a pharmacist at the counter.
After receiving her doctorate from the University of Pittsburgh School of Pharmacy, Karen Berger, Pharm.D., has worked in both chain and independent community pharmacies. She currently works at an independent pharmacy in New Jersey. Dr. Berger enjoys helping patients understand medical conditions and medications—both in person as a pharmacist, and online as a medical writer and reviewer.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved