What is Hydroxocobalamin: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Hydroxocobalamin overview

BRAND NAMES:

  • Vitamin B Complex 100

Generic Names:

  • Hydroxocobalamin Acetate

Uses:

  • Supplies your body with B vitamins. You might need extra B vitamins because of an illness or other medicines that you are using. You might not be getting enough B vitamins from the food you eat, or for other reasons. Given to people who cannot take B vitamins by mouth.

Therapeutic Classes:

  • Nutritive Agent, Parenteral Vitamin/Mineral Combination, Vitamin/Mineral Combination, Adult Formula, Vitamin B/Iron Combination, Vitamin B Combination

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Hydroxocobalamin used for?

What form(s) does Hydroxocobalamin come in

  • Injectable

What are common Hydroxocobalamin doses?

  • Vial 30ML of 1000MCG/ML

Common Hydroxocobalamin prescriptions

  • Hydroxocobalamin Acetate
    30ml of 1000mcg/ml vial

How to take Hydroxocobalamin

  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given through a needle placed in one of your veins. It can also be given as a shot into one of your muscles.

  • Injection routeA nurse or other health provider will give you this medicine.

  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given through a needle placed in one of your veins. It can also be given as a shot into one of your muscles.

  • Injection routeA nurse or other health provider will give you this medicine.

What to do if you miss a dose of Hydroxocobalamin

Hydroxocobalamin contraindications

  • You should not use this medicine if you have had an allergic reaction to any kind of vitamin B or to benzyl alcohol (a preservative).

Hydroxocobalamin warnings

  • Make sure your doctor knows if you are pregnant or breast feeding.

  • Chest pain, shortness of breath, or coughing up blood.

  • Numbness or weakness in your arm or leg, or on one side of your body.

  • Pain in your lower leg (calf).

  • Pain, itching, burning, swelling, or a lump under your skin where the needle is placed.

  • Swelling in your hands, ankles, or feet.

Hydroxocobalamin interactions

  • Make sure your doctor knows if you are pregnant or breast feeding.

Hydroxocobalamin side effects

Serious Side Effects

  • Pain in your lower leg (calf).

  • Pain, itching, burning, swelling, or a lump under your skin where the needle is placed.

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Chest pain, shortness of breath, or coughing up blood.

  • Numbness or weakness in your arm or leg, or on one side of your body.

  • Swelling in your hands, ankles, or feet.

Less Serious Side Effects

  • Pain where the shot was given.

  • Rash.

  • Diarrhea.

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