Hylenex Coupons & Prices

Hylenex is a prescription medication used together with fluids injected into the body to treat dehydration. This medication can be used as an aid in helping your body absorb other injected medicines. Hylenex comes in the form of an injectable solution and is currently not covered by Medicare. There is currently no generic alternative available. The approximate retail price of Hylenex is usually around $75.40 for 1, 1ml of 150unit/ml vial of Hylenex. Use a SingleCare Hylenex coupon to reduce the cost of Hylenex down to $56.57. SingleCare coupons are completely free and can be found online and on the mobile app for most prescription drugs.

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Hylenex coupon at Kroger Pharmacy
$59.57
$ 56.57
$3 off with signupwith signup

Show this free card to your pharmacist.

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Hylenex coupon at Harris Teeter Pharmacy
$59.57
$ 56.57
$3 off with signupwith signup

Save an extra $3 on any eligible prescription! Sign up for free

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Hylenex coupon at Costco Pharmacy
$63.92
$ 60.92
$3 off with signupwith signup
Hylenex coupon at Walmart Neighborhood Market Pharmacy
$64.10
$ 61.10
$3 off with signupwith signup
Hylenex coupon at Walmart Pharmacy
$64.10
$ 61.10
$3 off with signupwith signup
Hylenex coupon at Publix Pharmacy
$66.26
$ 63.26
$3 off with signupwith signup
$71.93
$ 68.93
$3 off with signupwith signup
$80.54
$ 77.54
$3 off with signupwith signup

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 12/05/2025

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About Hylenex

Hylenex is a prescription medication used together with fluids injected into the body to treat dehydration. This medication can be used as an aid in helping your body absorb other injected medicines. Hylenex comes in the form of an injectable solution and is currently not covered by Medicare. There is currently no generic alternative available. The approximate retail price of Hylenex is usually around $75.40 for 1, 1ml of 150unit/ml vial of Hylenex. Use a SingleCare Hylenex coupon to reduce the cost of Hylenex down to $56.57. SingleCare coupons are completely free and can be found online and on the mobile app for most prescription drugs.

Hylenex Price History & Information

Price History for Hylenex

1 count, vial, 1ml of 150unit/ml

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 1-Month Prices for Hylenex

1 count, vial, 1ml of 150unit/ml
PharmacyHylenex Retail PriceHylenex SingleCare Price
CVS Pharmacy$66.50$63.17
Walgreens$73.97$59.72
Kroger Pharmacy$67.00$55.82

These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Hylenex

Hylenex is a prescription medication used together with fluids injected into the body to treat dehydration. This medication can be used as an aid in helping your body absorb other injected medicines. Hylenex comes in the form of an injectable solution and is currently not covered by Medicare. There is currently no generic alternative available. The approximate retail price of Hylenex is usually around $75.40 for 1, 1ml of 150unit/ml vial of Hylenex. Use a SingleCare Hylenex coupon to reduce the cost of Hylenex down to $56.57. SingleCare coupons are completely free and can be found online and on the mobile app for most prescription drugs.

Hylenex FAQs

How much does Hylenex cost without insurance?

The average cost of Hylenex without insurance may be around $75.40 for 1, 1ml of 150unit/ml vial of Hylenex. You can purchase Hylenex for $56.57 for 1, 1ml of 150unit/ml vial of Hylenex when you use a SingleCare Hylenex savings card. These instant savings can be redeemed at a number of popular drugstores.

How much does Hylenex cost with insurance?

The cost of Hylenex with your insurance plan generally depends on the level of coverage you have and the type of health insurance policy you are enrolled in. If you need help to determine the cost of Hylenex with insurance, just visit your local pharmacy and ask your pharmacist to check the exact prescription cost. Using a SingleCare Hylenex savings card can also help you to save money by paying $56.57 for your Hylenex prescription.

Does Medicare cover Hylenex and how much does it cost?

Hylenex is not typically covered by Medicare. If you're a patient that is interested in purchasing this medication, you may have to pay the full cash price of $75.40 for 1, 1ml of 150unit/ml vial of Hylenex. SingleCare can help you to reduce this total and save on your overall medication costs. Simply use our SingleCare Hylenex discount card at participating neighborhood pharmacies and pay $56.57 for Hylenex.

Is there a generic of Hylenex?

Hylenex is a brand-name prescription drug manufactured by Halozyme Therapeutics, Inc. There is currently no generic alternative available.

What is Hylenex?

Hylenex is an FDA-approved medication used to increase the dispersion and absorption of other injected drugs. One of its primary uses is in the treatment of dehydration. It is also used to help contrast dyes in your body show more clearly on certain types of x-rays or scans. This medication works by helping your body to absorb fluids to treat dehydration. Hyaluronidase is the active ingredient in this medication.

Hylenex is given as an injection into a muscle, or into other tissues of the body. This injection is usually administered by a healthcare provider in a medical setting. This medication should not be injected into a vein. Your doctor will recommend an appropriate dose for you based on an assessment of your current medical condition, other drugs you are currently taking, and your response to treatment.

Before receiving Hylenex, tell your doctor if you are using furosemide, phenytoin, or anxiety medications such as Valium and Xanax. Serious drug interactions can occur if medications such as these are used together with Hylenex.

What are the side effects of Hylenex?

Pain, swelling, and redness may develop where the Hylenex injection was administered. Tell your doctor right away if you experience swelling in your hands, feet, or other areas of the body.

Serious allergic reactions to this medication are usually rare. However, you should seek immediate medical attention if you begin to experience symptoms of a serious allergic reaction such as itching, rash, swelling in your face or throat, severe dizziness, tightness in your chest, or trouble breathing.

Talk to your doctor or healthcare provider for professional medical advice on the risks and benefits involved with using Hylenex as this is not a complete list of side effects.

Where are Hylenex coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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