Guaifenesin ER Coupons & Prices

Mucus Relief

Guaifenesin ER is a long-acting version of an expectorant that works by loosening congestion in your chest and throat caused by the common cold or flu. Guaifenesin ER is also available over-the-counter under the brand names Mucinex, Guaifenex LA, and various store brands that include terms like long-acting, extended release, or 12-hour in their names. You can purchase Guaifenesin ER at a retail price of about $21.94 for 20, 600mg tablet extended release 12 hours. If you are looking to save money on your Guaifenesin ER price, you could use a SingleCare Guaifenesin ER coupon when you refill your Guaifenesin ER prescription. With our free coupon you pay as little as $14.09 for 20, 600mg tablet extended release 12 hours of Guaifenesin ER at your local pharmacy.

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0.5 box20 tablets extended release 12 hourEdit

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Guaifenesin ER coupon at Kroger Pharmacy
$17.09
$ 14.09
$3 off with signupwith signup

Show this free card to your pharmacist.

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Guaifenesin ER coupon at Harris Teeter Pharmacy
$17.09
$ 14.09
$3 off with signupwith signup

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Guaifenesin ER coupon at Food Lion Pharmacy
$ 15.11
Guaifenesin ER coupon at Publix Pharmacy
$18.86
$ 15.86
$3 off with signupwith signup
Guaifenesin ER coupon at Costco Pharmacy
$ 17.11
Guaifenesin ER coupon at Walgreens Pharmacy
$24.38
$ 21.38
$3 off with signupwith signup

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 02/03/2026

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About Guaifenesin ER

Guaifenesin ER is a long-acting version of an expectorant that works by loosening congestion in your chest and throat caused by the common cold or flu. Guaifenesin ER is also available over-the-counter under the brand names Mucinex, Guaifenex LA, and various store brands that include terms like long-acting, extended release, or 12-hour in their names. You can purchase Guaifenesin ER at a retail price of about $21.94 for 20, 600mg tablet extended release 12 hours. If you are looking to save money on your Guaifenesin ER price, you could use a SingleCare Guaifenesin ER coupon when you refill your Guaifenesin ER prescription. With our free coupon you pay as little as $14.09 for 20, 600mg tablet extended release 12 hours of Guaifenesin ER at your local pharmacy.

Guaifenesin ER Price History & Information

Price History for Guaifenesin Er (Generic) & Mucus Relief (Branded Generic)

20 count, tablet extended release 12 hour, 600mg

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 1-Month Prices for Guaifenesin Er (Generic) & Mucus Relief (Branded Generic)

20 count, tablet extended release 12 hour, 600mg
PharmacyMucus Relief Retail PriceGuaifenesin Er Retail PriceGuaifenesin Er SingleCare Price
Walmart$5.80--
Walgreens-$11.76$7.05
Kroger Pharmacy$9.20$16.90$14.69
Albertsons Pharmacy-$21.60$14.20

These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Guaifenesin ER

Guaifenesin ER is a long-acting version of an expectorant that works by loosening congestion in your chest and throat caused by the common cold or flu. Guaifenesin ER is also available over-the-counter under the brand names Mucinex, Guaifenex LA, and various store brands that include terms like long-acting, extended release, or 12-hour in their names. You can purchase Guaifenesin ER at a retail price of about $21.94 for 20, 600mg tablet extended release 12 hours. If you are looking to save money on your Guaifenesin ER price, you could use a SingleCare Guaifenesin ER coupon when you refill your Guaifenesin ER prescription. With our free coupon you pay as little as $14.09 for 20, 600mg tablet extended release 12 hours of Guaifenesin ER at your local pharmacy.

Guaifenesin ER FAQs

Medically reviewed by Jeff FortnerPharm.D.
Licensed Pharmacist

How much is Guaifenesin ER with SingleCare?

The generic of Guaifenesin ER costs $14.09 for 20, 600mg tablet extended release 12 hours with a free Guaifenesin ER coupon from SingleCare. You could pay less depending on your Rx details. Use the dropdown menu above to update your prescription information (i.e., generic/brand, quantity, dosage, form) to get the most accurate prices of Guaifenesin ER with SingleCare at your local pharmacies.

How much does Guaifenesin ER cost without insurance?

Guaifenesin ER may cost around $21.94 for 20, 600mg tablet extended release 12 hours or even more if you do not have insurance coverage. Using a SingleCare Guaifenesin ER discount card can help you save on your prescription medication and pay $14.09 for 20, 600mg tablet extended release 12 hours when you use our discount card at neighborhood pharmacies such as CVS Pharmacy, Walmart Pharmacy, Kroger, and Walgreens.

How much does Guaifenesin ER cost with insurance?

The average cost of Guaifenesin ER with insurance tends to vary based on the type of health insurance plan you are enrolled in and the level of benefits you are entitled to. You may need to contact your insurance provider directly to get their exact cost of Guaifenesin ER and your copay. To save money on your Guaifenesin ER cost, you can use a SingleCare Guaifenesin ER coupon and redeem instant savings. With our Guaifenesin ER coupon card, you pay $14.09 for 20, 600mg tablet extended release 12 hours for your Guaifenesin ER refills at SingleCare participating pharmacies everywhere.

Does Medicare cover Guaifenesin ER?

Guaifenesin ER is generally not covered by Medicare plans since it is an over-the-counter medication. You can save on your out-of-pocket cost for Guaifenesin ER by using a Guaifenesin ER savings card with your purchase. With our savings card, you can pay our lowest price of $14.09 for 20, 600mg tablet extended release 12 hours for your Guaifenesin ER medication at the pharmacy counter.

Does Medicaid cover Guaifenesin ER?

Since Guaifenesin ER is an over-the-counter medication, Medicaid programs in most states do not cover the cost of this medication. Some states may cover it in certain circumstances, but the cost of Guaifenesin ER with Medicaid depends on a person’s plan, deductible, and the coverage stage they are in. Our SingleCare savings card can be used instead of Medicaid when Medicaid doesn’t cover Guaifenesin ER or if your copay with Medicaid is still higher than what you would pay with a SingleCare coupon. With our savings card, you can pay our lowest price of $14.09 for 20, 600mg tablet extended release 12 hours for your Guaifenesin ER medication at the pharmacy counter

What is the brand name for Guaifenesin ER?

Guaifenesin ER is a generic medication manufactured by various companies, including Akorn, Rugby, Palmetto State, and Amneal Pharmaceuticals, in the United States. You can also purchase Guaifenesin ER under the brand names Mucinex, Guaifenex LA, and various store brands that include terms like long-acting, extended release, or 12-hour in their names.

Ways to save on Guaifenesin ER

Cost-saving strategies for over-the-counter medications like Guaifenesin ER tablets include choosing generic or store-brand versions and using discount programs such as SingleCare, which offers free savings without requiring insurance coverage. With our singleCare savings card, you can pay our lowest price of $14.09 for 20, 600mg tablet extended release 12 hours for your Guaifenesin ER medication.

Still, there are other ways to reduce costs:

  • Opt for generic or store-brand extended-release tablets. They contain the same active ingredient and dosage as brand-name products (such as Mucinex) but typically cost much less.

  • Watch for retailer promotions. Pharmacies, supermarkets, and big-box stores often run sales or offer loyalty points on cold, cough, and congestion medicines, including Guaifenesin ER tablets.

  • Use a health savings account (HSA) or flexible spending account (FSA). Guaifenesin ER tablets may be eligible for reimbursement, allowing you to use pre-tax funds to lower your overall cost.

  • Search for coupons or rebates. Some brands or retailers offer promotional discounts that can reduce the price of Guaifenesin ER.

  • Purchase larger-count bottles. Buying multi-packs or higher-count containers often lowers the cost per tablet, especially during seasons when you anticipate needing symptom relief.

Is there a cheaper alternative to Guaifenesin ER?

For OTC generic alternatives to Guaifenesin ER, you can choose other formulations that either contain the same active ingredient (guaifenesin) or are in the same drug class (expectorants) and are used to treat the same conditions (chest congestion and mucus relief). Examples include immediate-release guaifenesin tablets or caplets in a range of strengths (e.g., 200 mg, 400 mg, 600 mg) that loosen and thin mucus throughout the day but require more frequent dosing. Generic guaifenesin syrup or liquid expectorant formulations are also available if you prefer a liquid form for mucus relief. Additionally, there are combination OTC generics that include guaifenesin paired with other active ingredients, such as a cough suppressant (dextromethorphan) for people who want both expectorant and cough relief in one product. All of these options share the same mechanism of action as Guaifenesin ER but are sold as generic formulations, making them generally more affordable.

How to use SingleCare for Guaifenesin ER

SingleCare coupons are accepted at most national pharmacies and grocery stores, such as Walgreens, Kroger, Walmart, CVS, Safeway, and more. Just text, email, print, or save your free Guaifenesin ER coupon to your digital wallet and show your pharmacist at the counter. 

Medically reviewed by Jeff FortnerPharm.D.
Licensed Pharmacist

Jeff Fortner, Pharm.D., focuses his practice and research on pharmaceutical compounding, patient-centered care in the community setting, and pharmacist-provided clinical services. He maintains a practice site at an independent community pharmacy that also specializes in non-sterile compounding and long-term care medication preparation. Dr. Fortner enjoys spending time with his wife and two young daughters, trying and sharing new craft beers, reading sci-fi/fantasy fiction, and cycling.

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Where are Guaifenesin ER coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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