Imbruvica Coupons & Prices

Imbruvica is a brand-name prescription drug used to treat certain types of lymphomas and leukemias, as well as macroglobulinemia, a condition in which the blood is filled with large proteins, as well as complications of bone marrow transplants. The active ingredient in Imbruvica, ibrutinib, works by blocking a protein that is critical to the functioning and growth of the cancer cells. the Imbruvica cost is normally $21,313.08 at full price. A SingleCare Imbruvica coupon reduces that price to $9,695.31. You can find more information in our FAQs below.

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Imbruvica coupon at Kroger Pharmacy
$9698.31
$ 9,695
$3 off with signupwith signup

Show this free card to your pharmacist.

This coupon is not insurance.
Imbruvica coupon at Harris Teeter Pharmacy
$9698.31
$ 9,695
$3 off with signupwith signup
Imbruvica coupon at Walgreens Pharmacy
$10056.87
$ 10,054
$3 off with signupwith signup
Imbruvica coupon at Food Lion Pharmacy
$ 10,118
Imbruvica coupon at Publix Pharmacy
$10236.52
$ 10,234
$3 off with signupwith signup
Imbruvica coupon at Walmart Neighborhood Market Pharmacy
$10412.44
$ 10,409
$3 off with signupwith signup
$10412.44
$ 10,409
$3 off with signupwith signup
$10471.39
$ 10,468
$3 off with signupwith signup

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 03/20/2026

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About Imbruvica

Imbruvica is a brand-name prescription drug used to treat certain types of lymphomas and leukemias, as well as macroglobulinemia, a condition in which the blood is filled with large proteins, as well as complications of bone marrow transplants. The active ingredient in Imbruvica, ibrutinib, works by blocking a protein that is critical to the functioning and growth of the cancer cells. the Imbruvica cost is normally $21,313.08 at full price. A SingleCare Imbruvica coupon reduces that price to $9,695.31. You can find more information in our FAQs below.

About Imbruvica

Imbruvica is a brand-name prescription drug used to treat certain types of lymphomas and leukemias, as well as macroglobulinemia, a condition in which the blood is filled with large proteins, as well as complications of bone marrow transplants. The active ingredient in Imbruvica, ibrutinib, works by blocking a protein that is critical to the functioning and growth of the cancer cells. the Imbruvica cost is normally $21,313.08 at full price. A SingleCare Imbruvica coupon reduces that price to $9,695.31. You can find more information in our FAQs below.

Imbruvica FAQs

How much does Imbruvica cost without insurance?

Imbruvica normally costs $21,313.08. That same prescription will cost $9,695.31 using a SingleCare savings card, which you can use at major pharmacies throughout the country, such as Target, Longs Drugs, Walmart, Kroger, and others.

How much does Imbruvica cost with insurance?

The copay cost of Imbruvica will depend on your insurance plan and could be very high. Ask your pharmacist to compare your Imbruvica insurance copay to your SingleCare Imbruvica coupon. With SingleCare, Imbruvica costs only $9,695.31, which may save you more money than using insurance.

Does Medicare cover Imbruvica and how much does it cost?

Medicare Advantage and Medicare Part D prescription drug insurance plans usually provide coverage for Imbruvica, but the copay may be high. If you don't have coverage for Imbruvica, a SingleCare Imbruvica is a reliable way to save money. With SingleCare, the price of Imbruvica is $9,695.31 for each refill of 28, 420mg tablets.

Is there a generic of Imbruvica?

Imbruvica is a brand-name prescription drug with the active ingredient, ibrutinib. Generic ibrutinib is not available at this time.

What is Imbruvica?

Imbruvica is a brand-name prescription drug used to treat certain types of lymphomas and leukemias, namely mantle cell lymphoma, chronic lymphocytic leukemia, marginal zone lymphoma, and lymphocytic lymphoma. All of these cancers produce too many immature and low-functioning white blood cells, either lymphocytes (lymphoma) or leukocytes (leukemia).

Imbruvica is also prescribed to treat Waldenstrom's macroglobulinemia, a type of white blood cell cancer similar to leukemia. The bone marrow produces too many defective white blood cells that fill the bloodstream with large proteins called antibodies. Eventually, the blood becomes too thick to pass through small blood vessels.

Imbruvica is also prescribed to treat complications with bone marrow transplants called “chronic graft versus host disease,” a condition in which the transplanted bone marrow “turns against” the patient and produces white blood cells specifically programmed to destroy the organs and tissues in the patient's body.

The active ingredient in Imbruvica, ibrutinib, belongs to a class of anti-cancer drugs called tyrosine kinase inhibitors. Ibrutinib works by blocking a protein that signals a cell to divide and produce new cells. It's believed that these proteins, tyrosine kinases, become overactive in cancer cells. Blocking this protein slows or stops the growth of tumors.

Imbruvica is taken as a tablet or capsule once a day until there is sufficient progress made against cancer or until the patient can no longer safely take Imbruvica.

What are the side effects of Imbruvica?

Common side effects of Imbruvica include, but are not limited to, nausea, diarrhea, constipation, bruising, indigestion, headache, dizziness, cough, shortness of breath, fever, swelling, joint pain, muscle pain, muscle spasms, anemia, decreased appetite, dehydration, fatigue, and hand-foot skin reaction (a dose-dependent condition involving stinging, tingling, pain, dry skin, cracked skin, thickened skin, swelling, and blistering on the palms of the hand and soles of the feet).

Severe side effects include low platelet counts, which put the patient at risk for bleeding problems, high blood pressure, and increased risk of infections other cancers. Imbruvica kills off cancer cells very quickly, which may fill the bloodstream with the contents of these dead cancer cells. This may cause tumor lysis syndrome, a dangerous condition in which the cancer cell contents poison the body, leading to kidney failure, high blood potassium, low blood calcium, heart problems, and seizures.

Allergic reactions are rare. Watch for important signs of an allergic reaction, such as fever, sore throat, swelling, itching, or rash, and talk to your doctor immediately.

Where are Imbruvica coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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