What is Isovue-300? Uses, warnings & side effects

Updated May 14, 2025  •  Published Apr 11, 2021

Isovue-300 overview

BRAND NAMES:

  • Definity, Isovue-200, Isovue-250, Isovue-300, Isovue-370, Isovue-M 200, Isovue-M 300, Isovue Multipack-250, Isovue Multipack-300, Isovue Multipack-370, Omnipaque 140, Omnipaque 180, Omnipaque 240, Omnipaque 300, Omnipaque 350

Generic Names:

  • Isovue-300

Uses:

  • Helps parts of your body show up better during imaging tests.

Therapeutic Classes:

  • Diagnostic Agent, Radiological Contrast Media, Radiological Ionic Contrast Media, Radiological Non-Ionic Contrast Media

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Isovue-300 used for?

What form(s) does Isovue-300 come in?

  • Injectable

What are common Isovue-300 dosages?

  • Glass Cont 150ML of 61%

  • Glass Cont 500ML of 61%

How to take Isovue-300

  • Injection routeA nurse or other health provider will give you this medicine. It is given through a needle placed in an artery or a vein.

What to do if you miss a dose of Isovue-300

Isovue-300 contraindications - Who shouldn't take Isovue-300?

  • This medicine is not right for everyone. You should not receive it if you had an allergic reaction to any contrast dye.

Isovue-300 warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart or blood vessel problems, heart failure, a blood disorder (including anemia or sickle cell disease), diabetes, lung disease, thyroid problems, multiple sclerosis, pheochromocytoma, or multiple myeloma. Tell your doctor if you have a history of stroke, heart attack, or seizures. Tell your doctor if you have asthma, hay fever, or an allergy to any food or iodine.

  • This medicine may cause the following problems: Kidney problemsBlood clotting problemsChanges in heart rhythm

  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

  • Fast, slow, or uneven heartbeat

  • Lightheadedness, dizziness, fainting

  • Muscle stiffness or weakness, stiff joints or trouble moving, bone pain

  • Numbness or weakness on one side of your body, pain in your lower leg (calf)

  • Pain, itching, burning, redness, swelling, or a lump under your skin where the needle is placed

  • Skin rash, swelling, hardness, tightness, burning, or itching, red or dark patches

  • Sudden or severe headache, problems with vision, speech, or walking

Isovue-300 interactions & what to avoid when taking Isovue-300

  • There are many medicines that can interact with a contrast dye. Make sure your doctor knows the names of all the medicines you use, especially metformin or a beta-blocker medicine.

  • Tell your doctor if you have recently received any other contrast dyes or medicines.

  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

Isovue-300 side effects - How does Isovue-300 make you feel?

Serious Side Effects

  • Muscle stiffness or weakness, stiff joints or trouble moving, bone pain

  • Skin rash, swelling, hardness, tightness, burning, or itching, red or dark patches

  • Sudden or severe headache, problems with vision, speech, or walking

  • Numbness or weakness on one side of your body, pain in your lower leg (calf)

  • Pain, itching, burning, redness, swelling, or a lump under your skin where the needle is placed

  • Lightheadedness, dizziness, fainting

  • Chest pain, trouble breathing, coughing up blood

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Decrease in how much or how often you urinate, bloody or cloudy urine, lower back or side pain

  • Fast, slow, or uneven heartbeat

Less Serious Side Effects

  • Headache

  • Warmth or redness in your face, neck, arms, or upper chest

  • Mild feeling of burning, warmth, coldness when the medicine is injected

  • Nausea, vomiting

Subscribe to our savings newsletter

Health education, drug info, wellness & more

By clicking 'Subscribe', I agree to SingleCare's Terms & Conditions.