Kaletra is a brand-name prescription combination drug used to control the underlying viral infection that causes HIV/AIDS. Kaletra combines two prescription drugs—lopinavir and ritonavir—that prevent the HIV virus from reproducing itself. Kaletra costs $1,272.7, but a SingleCare Kaletra coupon reduces that cost to $364.20 per 120, 200-50mg tablets.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 12/20/2025
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Kaletra is a brand-name prescription combination drug used to control the underlying viral infection that causes HIV/AIDS. Kaletra combines two prescription drugs—lopinavir and ritonavir—that prevent the HIV virus from reproducing itself. Kaletra costs $1,272.7, but a SingleCare Kaletra coupon reduces that cost to $364.20 per 120, 200-50mg tablets.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Kaletra is a brand-name prescription combination drug used to control the underlying viral infection that causes HIV/AIDS. Kaletra combines two prescription drugs—lopinavir and ritonavir—that prevent the HIV virus from reproducing itself. Kaletra costs $1,272.7, but a SingleCare Kaletra coupon reduces that cost to $364.20 per 120, 200-50mg tablets.
The cash price of Kaletra is $1,272.7 for uninsured patients. For uninsured customers, however, federal ADAP (AIDS Drug Assistance Program) will help with some or all of the Kaletra cost. The HarborPath ADAP Waiting List Program may be able to help patients with their Kaletra prescription when state ADAP funding falls short. For uninsured patients on the ADAP waiting list who cannot affordably fill their prescription, a SingleCare Kaletra coupon reduces the cost to $364.20.
As a high-cost prescription drug, Kaletra copays may vary widely depending on your insurance plan and could be very high. With SingleCare, Kaletra costs $364.20, which may be lower than your copay with your insurance company. So ask your local pharmacist to compare your insurance copay to pricing with a free SingleCare discount card.
Kaletra is covered by Medicare Part D and Medicare Advantage, but the copay cost could be very high. Patients without Medicare prescription drug coverage or who can't afford the copay have many Kaletra patient assistance resources available, including ADAP, HarborPath, and other programs. For those who still cannot affordably fill their prescription, consider using a SingleCare Kaletra coupon. With our prescription discount card, the price of Kaletra is only $364.20.
The active ingredients in Kaletra are lopinavir and ritonavir. There is no generic version of Kaletra available at this time.
Kaletra (lopinavir-ritonavir) is an FDA-approved combination drug used to control the underlying viral infection that causes HIV/AIDS. Kaletra combines two prescription drugs—lopinavir and ritonavir– that prevent the human immunodeficiency virus from reproducing itself.
The HIV/AIDs virus directly attacks the body's immune system, so patients become vulnerable to secondary infections and cancers that ultimately will cause the patient's death. Reducing the amount of HIV virus in the body helps the immune system to recover or maintain itself, so the body is able to effectively fight off the cancers and infections that result from HIV/AIDS infections.
Kaletra is taken as a fixed-dose capsule, tablet, or oral solution. Depending on the dose, Kaletra is taken once or twice a day. A healthcare professional will determine the best dosage of Kaletra for you.
The most common side effects of Kaletra are diarrhea, stomach upset, nausea, vomiting, drowsiness, dizziness, skin rash, vertigo, weakness, trouble sleeping, muscle aches, headaches, joint pain, overactive thyroid, liver problems, pancreas problems, increased cholesterol, and high blood sugar.
Mental and mood changes include anxiety, sleep problems, strange dreams, and decreased sex drive.
Allergic reactions are rare but potentially severe, including Stevens-Johnson syndrome, a potentially life-threatening reaction involving body-wide blistering, peeling, rash, fever, and other symptoms. Discontinue Kaletra if any allergic symptoms, such as rash, swelling, or trouble breathing, are experienced.
This is not a complete list of side effects. Your physician will provide medical advice and address your concerns regarding potential side effects.
SingleCare is accepted at most national pharmacies and grocers, including the following:
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