Kaletra is a brand-name prescription combination drug used to control the underlying viral infection that causes HIV/AIDS. Kaletra combines two prescription drugs—lopinavir and ritonavir—that prevent the HIV virus from reproducing itself. Kaletra costs $1,272.7, but a SingleCare Kaletra coupon reduces that cost to $358.80 per 120, 200-50mg tablets.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 05/19/2026
Kaletra is a brand-name prescription combination drug used to control the underlying viral infection that causes HIV/AIDS. Kaletra combines two prescription drugs—lopinavir and ritonavir—that prevent the HIV virus from reproducing itself. Kaletra costs $1,272.7, but a SingleCare Kaletra coupon reduces that cost to $358.80 per 120, 200-50mg tablets.
Kaletra is a brand-name prescription combination drug used to control the underlying viral infection that causes HIV/AIDS. Kaletra combines two prescription drugs—lopinavir and ritonavir—that prevent the HIV virus from reproducing itself. Kaletra costs $1,272.7, but a SingleCare Kaletra coupon reduces that cost to $358.80 per 120, 200-50mg tablets.
The cash price of Kaletra is $1,272.7 for uninsured patients. For uninsured customers, however, federal ADAP (AIDS Drug Assistance Program) will help with some or all of the Kaletra cost. The HarborPath ADAP Waiting List Program may be able to help patients with their Kaletra prescription when state ADAP funding falls short. For uninsured patients on the ADAP waiting list who cannot affordably fill their prescription, a SingleCare Kaletra coupon reduces the cost to $358.80.
As a high-cost prescription drug, Kaletra copays may vary widely depending on your insurance plan and could be very high. With SingleCare, Kaletra costs $358.80, which may be lower than your copay with your insurance company. So ask your local pharmacist to compare your insurance copay to pricing with a free SingleCare discount card.
Kaletra is covered by Medicare Part D and Medicare Advantage, but the copay cost could be very high. Patients without Medicare prescription drug coverage or who can't afford the copay have many Kaletra patient assistance resources available, including ADAP, HarborPath, and other programs. For those who still cannot affordably fill their prescription, consider using a SingleCare Kaletra coupon. With our prescription discount card, the price of Kaletra is only $358.80.
The active ingredients in Kaletra are lopinavir and ritonavir. There is no generic version of Kaletra available at this time.
Kaletra (lopinavir-ritonavir) is an FDA-approved combination drug used to control the underlying viral infection that causes HIV/AIDS. Kaletra combines two prescription drugs—lopinavir and ritonavir– that prevent the human immunodeficiency virus from reproducing itself.
The HIV/AIDs virus directly attacks the body's immune system, so patients become vulnerable to secondary infections and cancers that ultimately will cause the patient's death. Reducing the amount of HIV virus in the body helps the immune system to recover or maintain itself, so the body is able to effectively fight off the cancers and infections that result from HIV/AIDS infections.
Kaletra is taken as a fixed-dose capsule, tablet, or oral solution. Depending on the dose, Kaletra is taken once or twice a day. A healthcare professional will determine the best dosage of Kaletra for you.
The most common side effects of Kaletra are diarrhea, stomach upset, nausea, vomiting, drowsiness, dizziness, skin rash, vertigo, weakness, trouble sleeping, muscle aches, headaches, joint pain, overactive thyroid, liver problems, pancreas problems, increased cholesterol, and high blood sugar.
Mental and mood changes include anxiety, sleep problems, strange dreams, and decreased sex drive.
Allergic reactions are rare but potentially severe, including Stevens-Johnson syndrome, a potentially life-threatening reaction involving body-wide blistering, peeling, rash, fever, and other symptoms. Discontinue Kaletra if any allergic symptoms, such as rash, swelling, or trouble breathing, are experienced.
This is not a complete list of side effects. Your physician will provide medical advice and address your concerns regarding potential side effects.
Kristi C. Torres, Pharm.D., is a 2005 graduate of The University of Texas at Austin. Her professional background includes academic teaching roles, district-level management for a nationwide pharmacy chain, and clinic-based pharmacy management. Dr. Torres has a wide range of experience in pharmacy operations and has traveled to many states to open and convert clinic-based pharmacies for one of the largest healthcare systems in the nation.
Currently, she works for Tarrytown Expocare Pharmacy in Austin, Texas, serving the intellectual and developmental disability community. There, she leads the order entry team, overseeing orders from across the country.
Dr. Torres began working in pharmacy at the age of 16 in a small East Texas town. She currently resides in Round Rock, Texas, with her daughter and a Shih-Tzu puppy.
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SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2026 SingleCare Administrators. All rights reserved