Lokelma is a prescription medication used to treat hyperkalemia, which is a condition where there is a high level of potassium in the blood. High potassium levels can cause symptoms such as nausea, muscle weakness, tiredness, and irregular heartbeats. There is currently no generic alternative available. The approximate retail price of Lokelma is usually around $44.23 per 1, 1 packet packet. Use a SingleCare Lokelma coupon to reduce your cost for Lokelma down to $30.08 for 1, 1 packet packet.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 12/05/2025
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Lokelma is a prescription medication used to treat hyperkalemia, which is a condition where there is a high level of potassium in the blood. High potassium levels can cause symptoms such as nausea, muscle weakness, tiredness, and irregular heartbeats. There is currently no generic alternative available. The approximate retail price of Lokelma is usually around $44.23 per 1, 1 packet packet. Use a SingleCare Lokelma coupon to reduce your cost for Lokelma down to $30.08 for 1, 1 packet packet.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Lokelma Retail Price | Lokelma SingleCare Price |
|---|---|---|
| CVS Pharmacy | $33.90 | $29.90 |
| Walmart | $34.46 | $30.34 |
| Walgreens | $34.97 | $31.14 |
| Kroger Pharmacy | $34.47 | $28.25 |
| Albertsons Pharmacy | $31.72 | $30.28 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Lokelma is a prescription medication used to treat hyperkalemia, which is a condition where there is a high level of potassium in the blood. High potassium levels can cause symptoms such as nausea, muscle weakness, tiredness, and irregular heartbeats. There is currently no generic alternative available. The approximate retail price of Lokelma is usually around $44.23 per 1, 1 packet packet. Use a SingleCare Lokelma coupon to reduce your cost for Lokelma down to $30.08 for 1, 1 packet packet.
Without insurance coverage, the average cost of Lokelma is around $44.23 per 1, 1 packet packet. SingleCare can help you to save on this total with our Lokelma savings cards. Pay only $30.08 for 1, 1 packet packet for your Lokelma prescription refill at participating pharmacies.
The average cost of Lokelma with insurance tends to vary based on the type of health insurance plan you are enrolled in and the benefits you are entitled to. You may need to contact your insurance provider directly to get an accurate cost for your Lokelma prescription. You can also save on Lokelma by using SingleCare's Lokelma coupons. Redeem prescription savings and pay just $30.08 for 1, 1 packet packet for Lokelma when you use your SingleCare coupon.
Lokelma is covered by many commercial insurance and Medicare Part D plans. Without coverage, the average cash price of Lokelma may be as high as $44.23 for 1, 1 packet packet. You can save on this total by using a SingleCare pharmacy discount card. Redeem prescription savings at participating pharmacies by using your SingleCare pharmacy discount card and pay just $30.08 for 1, 1 packet packet of Lokelma.
Lokelma is a brand-name prescription drug manufactured by AstraZeneca. There is currently no generic alternative available.
Lokelma (sodium zirconium cyclosilicate) is a prescription medication used to treat hyperkalemia. That is a condition where there is a high level of potassium in the blood. High potassium levels can cause symptoms such as nausea, muscle weakness, tiredness, and irregular heartbeats. This medication works directly in the intestines to remove excess potassium from the body. Lokelma does not work right away and should not be used to treat life-threatening high levels of potassium.
This medication comes in the form of an oral powder for reconstitution. Use this medication two hours after or two hours before taking other medications. Your doctor will recommend an appropriate dose for you based on an assessment of your current medical condition, other drugs you are currently taking, and your response to treatment.
This medication must be mixed before use. Open a packet and mix the powdered contents with water. Stir, then drink the mixture right away. If any powder is left in the glass, add more water, stir, and drink again. Repeat until no powder is left in the glass. Take it on a regular schedule as recommended by your healthcare provider.
Common side effects may include swelling in your feet, ankles, or hands. Check with your doctor or pharmacist if you experience any of these effects, and they persist or worsen. Many patients using this medication do not have any serious side effects.
Serious allergic reactions to this medication are usually rare. However, you should seek immediate medical attention if you begin to experience symptoms of a serious allergic reaction, such as itching, rash, swelling in your face or throat, severe dizziness, tightness in your chest, or trouble breathing.
Talk to your doctor or healthcare provider for full medical advice on the risks and benefits of using Lokelma as this is not a complete list of side effects.
Lokelma is typically taken three times a day for up to 48 hours. It starts to lower potassium levels within an hour, but the full effect can take up to two days. That’s why Lokelma is used for high but not life-threatening potassium levels.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved