Lotronex Coupons & Prices

Alosetron Hcl

Lotronex is a IBS Agent - Selective 5-HT3 Receptor Antagonists class medication manufactured by Legacy Pharma. The average counter price for Lotronex is $2,849.23 per 60, 0.5mg tablets, but you can pay $69.36 for 60, 0.5mg tablets of generic Lotronex with a SingleCare discount card. Lotronex is a trademark drug; Alosetron HCl is the generic variant of Lotronex.

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Lotronex coupon at CVS Pharmacy
$72.36
$ 69.36
$3 off with signupwith signup

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Lotronex coupon at Walgreens Pharmacy
$177.92
$ 174.92
$3 off with signupwith signup

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Lotronex coupon at Walmart Neighborhood Market Pharmacy
$192.26
$ 189.26
$3 off with signupwith signup
Lotronex coupon at Walmart Pharmacy
$192.26
$ 189.26
$3 off with signupwith signup
Lotronex coupon at Food Lion Pharmacy
$ 299.00
Lotronex coupon at Costco Pharmacy
$ 348.18
$405.62
$ 402.62
$3 off with signupwith signup
$405.62
$ 402.62
$3 off with signupwith signup
$1027.39
$ 1,024
$3 off with signupwith signup

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 02/16/2026

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About Lotronex

Lotronex is a IBS Agent - Selective 5-HT3 Receptor Antagonists class medication manufactured by Legacy Pharma. The average counter price for Lotronex is $2,849.23 per 60, 0.5mg tablets, but you can pay $69.36 for 60, 0.5mg tablets of generic Lotronex with a SingleCare discount card. Lotronex is a trademark drug; Alosetron HCl is the generic variant of Lotronex.

Lotronex Price History & Information

Price History for Lotronex (Brand) & Alosetron Hcl (Generic)

60 count, tablet, 0.5mg

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 1-Month Prices for Lotronex (Brand) & Alosetron Hcl (Generic)

60 count, tablet, 0.5mg
PharmacyAlosetron Hcl Retail PriceAlosetron Hcl SingleCare Price
CVS Pharmacy$1360.20$69.96
Walmart$334.20$192.00
Kroger Pharmacy$2067.00$405.60

These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Lotronex

Lotronex is a IBS Agent - Selective 5-HT3 Receptor Antagonists class medication manufactured by Legacy Pharma. The average counter price for Lotronex is $2,849.23 per 60, 0.5mg tablets, but you can pay $69.36 for 60, 0.5mg tablets of generic Lotronex with a SingleCare discount card. Lotronex is a trademark drug; Alosetron HCl is the generic variant of Lotronex.

Lotronex FAQs

How much is Lotronex with SingleCare?

The generic form of Lotronex costs $69.36 for 60, 0.5mg tablets with a free Lotronex coupon from SingleCare. But, you could reduce this cost more depending on your prescription information. Use the dropdown menu above to enter your prescription information (i.e., brand/generic, quantity, form, dosage) to see the most accurate prices of Lotronex with SingleCare at a pharmacy near you.

How much does Lotronex cost without insurance?

The standard retail price of Lotronex without health insurance is $2,849.23 per 60, 0.5mg tablets but you can save using a SingleCare Lotronex coupon to pay $69.36 for 60, 0.5mg tablets of generic Lotronex. Those without insurance can always use SingleCare for free Lotronex savings. You can also save on Lotronex by using the generic version of Lotronex if a generic version is available, Alosetron HCl, which typically costs dramatically less than Lotronex. 

How much does Lotronex cost with insurance?

Each individual insurance plan has different details and may or may not cover Lotronex. The cost of Lotronex with insurance coverage varies according to your plan - check with your insurance company for specific formulary coverage and payment guidance. If your insurance does not include Lotronex, you can use SingleCare to save money on Lotronex at your participating pharmacies. Additionally, you can also use SingleCare savings if you have Medicare or Medicaid. If Medicare or Medicaid doesn’t provide coverage your Lotronex prescription, try SingleCare instead. Go to the SingleCare website or app to compare the lowest price of Lotronex with SingleCare versus your Lotronex cost with insurance or Medicare.

How to use SingleCare for Lotronex

SingleCare coupons are accepted at most national pharmacies and grocers, including Walgreens, Kroger, Walmart, CVS, Safeway, and more. Text, email, print, or save your free Lotronex coupon to your mobile wallet and show your pharmacist when you pick up your prescription. 

What is the generic of Lotronex?

Lotronex is a trademark medication created by Legacy Pharma. The generic variant of Lotronex is Alosetron HCl and is significantly less expensive than the typical cost of Lotronex, which is $2,849.23 per 60, 0.5mg tablets, but uses the same active ingredients as Lotronex. Use a SingleCare prescription drug discount card to pay $69.36 for 60, 0.5mg tablets of generic Lotronex.

Where are Lotronex coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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