What is Morphine Concentrate? Uses, warnings & side effects

Updated May 14, 2025  •  Published Dec 30, 2020

Morphine Concentrate overview

BRAND NAMES:

  • Roxanol

Generic Names:

  • Morphine Sulfate (Concentrate)

Uses:

  • Treats moderate to severe pain. This medicine is a narcotic pain reliever.

Therapeutic Classes:

  • Analgesic, Antidiarrheal

Forms:

  • Capsule, Liquid, Tablet

How it’s taken:

  • By mouth

What is Morphine Concentrate used for?

What form(s) does Morphine Concentrate come in?

  • Capsule

  • Liquid

  • Tablet

What are common Morphine Concentrate dosages?

  • Bottle 30ML of 20MG/ML

  • Bottle 15ML of 100MG/5ML

  • Bottle 30ML of 100MG/5ML

  • Bottle 120ML of 100MG/5ML

  • Bottle 240ML of 100MG/5ML

Morphine Concentrate images - What does Morphine Concentrate look like?

  • Morphine Sulfate (Concentrate)
    118ml of 20mg/ml bottle

  • Morphine Sulfate (Concentrate)
    120ml of 100mg/5ml bottle

  • Morphine Sulfate (Concentrate)
    120ml of 20mg/ml bottle

  • Morphine Sulfate (Concentrate)
    15ml of 100mg/5ml bottle

  • Morphine Sulfate (Concentrate)
    240ml of 100mg/5ml bottle

  • Morphine Sulfate (Concentrate)
    240ml of 20mg/ml bottle

  • Morphine Sulfate (Concentrate)
    30ml of 100mg/5ml bottle

  • Morphine Sulfate (Concentrate)
    30ml of 20mg/ml bottle

How to take Morphine Concentrate

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • An overdose can be dangerous. Follow directions carefully so you do not get too much medicine at one time.

  • Oral routeIt is best to take this medicine with food or milk.

  • Capsule: If you cannot swallow the capsule whole, you may open it and mix the medicine pellets with a small amount of applesauce, pudding, juice, or water. Swallow the mixture right away, without chewing or crushing the pellets.

  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

  • Missed dose: If you miss a dose of this medicine, skip the missed dose and take your next dose at your usual time the next day. Do not double doses.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Store the medicine in a safe and secure place. Drop off any unused narcotic medicine at a drug take-back location right away. If you do not have a drug take-back location near you, flush any unused narcotic medicine down the toilet. Check your local drug store and clinics for take-back locations. You can also check the DEA web site for locations. Here is the link to the FDA safe disposal of medicines website: www.fda.gov/drugs/resourcesforyou/consumers/buyingusingmedicinesafely/ensuringsafeuseofmedicine/safedisposalofmedicines/ucm186187.htm

  • Oral liquid: Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.

  • Oral routeIt is best to take this medicine with food or milk.

  • An overdose can be dangerous. Follow directions carefully so you do not get too much medicine at one time.

  • Capsule: If you cannot swallow the capsule whole, you may open it and mix the medicine pellets with a small amount of applesauce, pudding, juice, or water. Swallow the mixture right away, without chewing or crushing the pellets.

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Store the medicine in a safe and secure place. Drop off any unused narcotic medicine at a drug take-back location right away. If you do not have a drug take-back location near you, flush any unused narcotic medicine down the toilet. Check your local drug store and clinics for take-back locations. You can also check the DEA web site for locations. Here is the link to the FDA safe disposal of medicines website: www.fda.gov/drugs/resourcesforyou/consumers/buyingusingmedicinesafely/ensuringsafeuseofmedicine/safedisposalofmedicines/ucm186187.htm

  • Oral liquid: Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.

  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

  • Missed dose: If you miss a dose of this medicine, skip the missed dose and take your next dose at your usual time the next day. Do not double doses.

What to do if you miss a dose of Morphine Concentrate

  • If you miss a dose or forget to take your medicine, take it as soon as you can. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.

  • Ask your pharmacist about the best way to dispose of medicine you do not use.

  • Keep all medicine away from children and never share your medicine with anyone.

Morphine Concentrate contraindications - Who shouldn't take Morphine Concentrate?

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to morphine, codeine, hydrocodone, dihydrocodeine, or oxycodone, or you have severe lung or breathing problems or paralytic ileus.

Morphine Concentrate warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart disease, low blood pressure, breathing problems or lung disease (such as asthma or COPD), Addison's disease, gallbladder problems, pancreas problems, thyroid problems, an enlarged prostate, trouble urinating, or stomach or bowel problems. Tell your doctor if you have a history of head injury, brain tumor, depression, seizures, or alcohol or drug abuse.

  • This medicine may cause the following problems:High risk of overdose, which can lead to deathRespiratory depression (serious breathing problem that can be life-threatening)Serotonin syndrome (when used with certain medicines)

  • This medicine can be habit-forming. Do not use more than your prescribed dose. Call your doctor if you think your medicine is not working.

  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.

  • This medicine could cause infertility. Talk with your doctor before using this medicine if you plan to have children.

  • This medicine may make you dizzy, drowsy, or lightheaded. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

  • This medicine may cause constipation, especially with long-term use. Ask your doctor if you should use a laxative to prevent and treat constipation.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Morphine Concentrate interactions & what to avoid when taking Morphine Concentrate

  • Do not use this medicine if you are using or have used an MAO inhibitor within the past 14 days.

  • Some medicines can affect how morphine works. Tell your doctor if you are using any of the following:Cimetidine, mirtazapine, quinidine, tramadol, trazodone, or verapamilDiuretic (water pill)Medicine to treat depressionPhenothiazine medicineTriptan medicine to treat migraine headaches

  • Do not drink alcohol while you are using this medicine.

  • Tell your doctor if you use anything else that makes you sleepy. Some examples are allergy medicine, narcotic pain medicine, and alcohol. Tell your doctor if you are also using buprenorphine, butorphanol, nalbuphine, pentazocine, a benzodiazepine, or a muscle relaxer.

  • This medicine may cause constipation, especially with long-term use. Ask your doctor if you should use a laxative to prevent and treat constipation.

Morphine Concentrate side effects - How does Morphine Concentrate make you feel?

Serious Side Effects

  • Trouble breathing or slow breathing

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Anxiety, restlessness, fast heartbeat, fever, sweating, muscle spasms, twitching, nausea, vomiting, diarrhea, seeing or hearing things that are not there

  • Blue lips, fingernails, or skin

  • Severe confusion, lightheadedness, dizziness, or fainting

  • Extreme dizziness or weakness, shallow breathing, slow or uneven heartbeat, sweating, cold or clammy skin, seizures

  • Severe constipation, stomach pain, or vomiting

Less Serious Side Effects

  • Nausea or vomiting

  • Mild sleepiness or tiredness

  • Mild constipation, nausea, or vomiting

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