Disulfiram is an FDA-approved, generic drug prescribed to manage chronic alcoholism in patients who want to be sober. It is a chemical deterrent to drinking. This drug is not a cure for alcoholism, but in combination with counseling and support, can help patients maintain sobriety. Disulfiram is harmless when taken alone, but causes acute and painful side effects only a few minutes after even a tiny amount of alcohol is consumed. These effects last for several hours and are more severe—and potentially life-threatening—if large amounts of alcohol are consumed. The retail price of Disulfiram is $159.82. However, a SingleCare Disulfiram coupon reduces that price to $35.58. Find out more about this and other ways to save money in our FAQs.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 12/05/2025
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Disulfiram is an FDA-approved, generic drug prescribed to manage chronic alcoholism in patients who want to be sober. It is a chemical deterrent to drinking. This drug is not a cure for alcoholism, but in combination with counseling and support, can help patients maintain sobriety. Disulfiram is harmless when taken alone, but causes acute and painful side effects only a few minutes after even a tiny amount of alcohol is consumed. These effects last for several hours and are more severe—and potentially life-threatening—if large amounts of alcohol are consumed. The retail price of Disulfiram is $159.82. However, a SingleCare Disulfiram coupon reduces that price to $35.58. Find out more about this and other ways to save money in our FAQs.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Disulfiram Retail Price | Disulfiram SingleCare Price |
|---|---|---|
| CVS Pharmacy | $104.10 | $77.10 |
| Walmart | $105.60 | $84.90 |
| Walgreens | $133.20 | $44.10 |
| Kroger Pharmacy | $125.92 | $77.10 |
| Albertsons Pharmacy | $123.60 | $63.30 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Disulfiram is an FDA-approved, generic drug prescribed to manage chronic alcoholism in patients who want to be sober. It is a chemical deterrent to drinking. This drug is not a cure for alcoholism, but in combination with counseling and support, can help patients maintain sobriety. Disulfiram is harmless when taken alone, but causes acute and painful side effects only a few minutes after even a tiny amount of alcohol is consumed. These effects last for several hours and are more severe—and potentially life-threatening—if large amounts of alcohol are consumed. The retail price of Disulfiram is $159.82. However, a SingleCare Disulfiram coupon reduces that price to $35.58. Find out more about this and other ways to save money in our FAQs.
At most pharmacies, the cash price of Disulfiram without insurance will be $159.82. A SingleCare savings card lowers that cost to a discount price of $35.58 for every 30, 250mg tablets.
Copay costs of Disulfiram differ depending on your insurance plan. With SingleCare, Disulfiram costs as little as $35.58 for 30, 250mg tablets. Ask your pharmacist to compare your insurance copay to your price using a free discount card from SingleCare. Your SingleCare price could be lower.
Medicare Part D and Medicare Advantage prescription drug insurance plans will cover generic Disulfiram, but usually not its brand-name version, Antabuse. If you don't have Medicare, SingleCare offers a Disulfiram coupon that every month reduces the cost of Disulfiram to $35.58.
Disulfiram is a generic prescription drug and is the active ingredient in the brand-name prescription drug, Antabuse.
Disulfiram is a generic drug prescribed to people with chronic alcoholism to act as a chemical deterrent. Disulfiram is harmless when taken alone, but causes acute and painful side effects only a few minutes after someone taking Disulfiram drinks even a small amount of alcohol: pounding headache, trouble breathing, fast heartbeat, low blood pressure, nausea, and severe vomiting. A severe Disulfiram-alcohol reaction can be fatal.
Disulfiram works by interfering with the body's ability to completely metabolize alcohol, leaving instead a fairly toxic chemical, acetaldehyde, to build up in the body. The effects kick in only a few minutes after the patient drinks alcohol and typically last for several hours.
Disulfiram is often started in a hospital or rehabilitation facility. Disulfiram should never be taken when the patient is drinking alcohol. The treatment should be started at least 12 hours after the last alcoholic beverage. The patient must be fully aware of the Disulfiram-alcohol reaction, and understand that drinking alcohol can cause severe reactions. The family and caregivers should also be educated. Alcohol or products containing alcohol cannot be ingested, this includes hidden sources of alcohol such as mouthwash, cough syrups, foods with alcohol (such as sauces), and even topical preparations like back rubs or shaving products. Disulfiram should not be taken with metronidazole. Disulfiram has other drug interactions too, so review all medications (including Rx, OTC, vitamins, and supplements) with your doctor before starting this drug. Disulfiram is active in the body for several weeks, so patients will not be able to drink alcohol for at least two weeks after discontinuing Disulfiram. While taking Disulfiram, the patient must carry a medical card that states they are taking Disulfiram. This lets emergency responders know that if the patient is disoriented or unconscious, they may be having a Disulfiram reaction. The card also tells responders not to administer alcohol or any preparations that contain alcohol, and lists supportive measures that can be used, such as oxygen inhalation.
The side effects of Disulfiram are minimal when taken alone and rarely experienced: drowsiness, skin rash, pimples, and a bad taste in the mouth.
When Disulfiram is taken with alcohol, side effects are unpleasant and potentially life-threatening: nausea, severe vomiting, neck pain, throbbing headache, fast heartbeat, fluttering heartbeat, sweating, thirst, shortness of breath, confusion, blurred vision, and chest pain. The Disulfiram-alcohol reaction can cause cardiovascular effects such as severe chest pain, low blood pressure, and heart failure or a heart attack. The Disulfiram-alcohol reaction also slows and may stop breathing or cause death.
Consult your doctor or healthcare professional for additional drug information and medical advice associated with taking Disulfiram.
After receiving her doctorate from the University of Pittsburgh School of Pharmacy, Karen Berger, Pharm.D., has worked in both chain and independent community pharmacies. She currently works at an independent pharmacy in New Jersey. Dr. Berger enjoys helping patients understand medical conditions and medications—both in person as a pharmacist, and online as a medical writer and reviewer.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved