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Myfembree
Myfembree
Treats heavy menstrual bleeding caused by uterine fibroids.
Endocrine-Metabolic Agent, Estrogen/Progestin Combination
Tablet
By mouth
Tablet
Tablet 40-1-0.5MG
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
Your doctor will tell you how much medicine to use. Do not use more than directed. Take the tablet at about the same time each day.
You may receive other medicines (including calcium or vitamin D supplements) to help reduce bone loss.
Use this medicine within 7 days from the start of your menstrual period.
This medicine is not right for everyone. Do not use it if you have had an allergic reaction to relugolix, estradiol, or norethindrone, or if you are pregnant. Do not use it if you have vaginal bleeding that has not been checked by a doctor, liver disease, uncontrolled high blood pressure, problems with blood clots, breast cancer, migraine headaches, or osteoporosis (weak bones).
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
This medicine may cause the following problems:Increased risk of blood clots, heart attack, or strokeLower bone mineral densityIncreased risk of breast cancerChanges in mood or behavior, including thoughts of suicideLiver problemsGallbladder diseaseHigh blood pressureChanges in menstrual bleeding, which may decrease the ability to know if you are pregnantHair lossHigh cholesterol and blood sugar
Keep all medicine out of the reach of children. Never share your medicine with anyone.
It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. This medicine may increase your risk of early pregnancy loss. Your doctor may give you a pregnancy test before you start using this medicine to make sure you are not pregnant. Birth control pills may not work as well to prevent pregnancy when used with this medicine. Use another form of birth control (including condoms or spermicide) during treatment and for at least 1 week after the last dose.
Tell your doctor if you are breastfeeding, or if you have blood vessel disease, high cholesterol, diabetes, mental problems, gallbladder problems, jaundice (yellow skin or eyes) caused by pregnancy or birth control pills, or a history of fractures. Tell your doctor if you smoke or if you will be having a surgery.
Make sure any doctor or dentist who treats you knows that you are using this medicine.
Take this medicine at least 6 hours before taking other medicines called P-gp inhibitors. Ask your doctor about these medicines.
Some medicines can affect how relugolix/estradiol/norethindrone works. Tell your doctor if you are using erythromycin or rifampin.
Serious Side Effects
Breast lumps, pain, swelling, tenderness, or discharge
Rapid weight gain, swelling in your hands, ankles, or feet
Thinning or loss of hair
Dry mouth, increased hunger, thirst, or urination
Sudden or severe headache, problems with vision, speech, or walking
Stomach pain, nausea, vomiting, lightheadedness
Light, heavy, or irregular bleeding during monthly periods
Numbness or weakness in your arm or leg, or on one side of your body, pain in your lower leg (calf)
Bone pain, decreased height
Dark urine or pale stools, loss of appetite, yellow skin or eyes
Chest pain or tightness, trouble breathing, coughing up blood
Extreme energy or restlessness, confusion, agitation, unusual mood or behavior, thoughts or attempts at killing oneself
Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Less Serious Side Effects
Decreased interest in sex
Feeling of warmth, redness of the skin, sweating
Health education, drug info, wellness & more
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
© 2025 SingleCare Administrators. All rights reserved
© 2025 SingleCare Administrators. All rights reserved