Naltrexone is an opioid agonist that is used to treat alcohol and opioid use disorders. It is available by prescription only. The average cost of Naltrexone without insurance is $164.62 for 30, 50mg tablets, but you can use a Naltrexone coupon from SingleCare to pay as little as $36.99 for 30, 50mg tablets.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 03/20/2026
Naltrexone is an opioid agonist that is used to treat alcohol and opioid use disorders. It is available by prescription only. The average cost of Naltrexone without insurance is $164.62 for 30, 50mg tablets, but you can use a Naltrexone coupon from SingleCare to pay as little as $36.99 for 30, 50mg tablets.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Naltrexone Hcl Retail Price | Naltrexone Hcl SingleCare Price |
|---|---|---|
| CVS Pharmacy | $108.91 | $52.01 |
| Walmart | $79.90 | $37.10 |
| Walgreens | $59.39 | $46.60 |
| Kroger Pharmacy | $86.14 | $48.01 |
| Albertsons Pharmacy | $129.87 | $34.20 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Naltrexone is an opioid agonist that is used to treat alcohol and opioid use disorders. It is available by prescription only. The average cost of Naltrexone without insurance is $164.62 for 30, 50mg tablets, but you can use a Naltrexone coupon from SingleCare to pay as little as $36.99 for 30, 50mg tablets.
The generic form of Naltrexone costs $36.99 for 30, 50mg tablets with a free Naltrexone coupon from SingleCare. You could lower this cost more depending on your Rx details. Use the dropdown menu above to enter your Rx details (i.e., generic/brand, quantity, dosage, form) to see the most accurate prices of Naltrexone with SingleCare near you.
The Naltrexone price without insurance coverage is about $164.62 for 30, 50mg tablets. However, a SingleCare coupon for Naltrexone can reduce that price to $36.99 for 30, 50mg tablets at participating local pharmacies.
Naltrexone is usually covered by most insurance plans. As a generic medication, the copay is not typically expensive with insurance, but the cost may depend on the plan details and deductible, if applicable. If the copay is too high, consider using a SingleCare Naltrexone coupon without insurance and pay as little as $36.99 for 30, 50mg tablets.
Medicare drug plans typically cover Naltrexone. The cost should be low as a generic medication, but it may be affected by the plan’s deductible and details. If the out-of-pocket costs are challenging, use a SingleCare Naltrexone coupon instead of Medicare. This can bring the cost down to $36.99 for 30, 50mg tablets.
Medicaid usually covers Naltrexone, but the copay depends on the plan and state. Out-of-pocket costs should be minimal. If coverage or cost is an issue, consider using a SingleCare prescription discount card instead of Medicaid.
Naltrexone was available under the brand names ReVia and Depade, but both have been discontinued in the U.S. Naltrexone is also available under the brand name Vivitrol, which is given as a monthly injection in a health care provider’s office.
If Naltrexone is still too expensive, use a free SingleCare savings card to pay as little as $36.99 for 30, 50mg tablets. Signing up for SingleCare’s loyalty program can help you save even more each month.
There are other potential ways to save on Naltrexone, such as:
Asking your healthcare provider for free samples, although this is not a long-term solution to reduce savings
Shopping around to see the cost of Naltrexone at different pharmacies
Applying for Medicare Extra Help if eligible
Using a flexible spending account (FSA) or health savings account (HSA) if available
Switching to an alternative medication
Although Naltrexone is generic and typically inexpensive, there may be cheaper alternatives. Additionally, there may be a treatment option that works better for you, as everyone has individualized treatment needs. Suboxone (buprenorphine/naloxone) and Methadose (methadone) are alternatives to Naltrexone for opioid use disorder, but they are both controlled medications and may require additional steps before obtaining prescriptions for them. Acamprosate and disulfiram are alternative treatments for alcohol use disorder.
SingleCare is accepted at most national pharmacies and grocers, i.e., Walgreens, Kroger, Walmart, CVS, Safeway, and more. Just text, email, print, or save your free Naltrexone coupon to your digital wallet and show a pharmacist when you pick up your prescription.
Josephine Bawab, Pharm.D., graduated from Virginia Commonwealth University School of Pharmacy. She began working in community pharmacy in 2012 and has worked for multiple chain pharmacies since then. She is passionate about helping patients and precepting students. She currently works and resides in Virginia, where she is just a few minutes away from the beach.
...SingleCare is accepted at most national pharmacies and grocers, including the following:
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SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2026 SingleCare Administrators. All rights reserved