What is Nerlynx: Uses, Warnings & Interactions

How to take Nerlynx

• Missed dose: If you miss a dose of this medicine, skip the missed dose and take your next dose at your usual time.

• Oral routeIt is best to take this medicine with food or milk.

• Swallow the tablet whole. Do not crush, break, or chew it. Take it at the same time each day.

• Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

• Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

• Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

• You should start taking medicines to help prevent diarrhea (including loperamide) during your first dose of neratinib. Continue taking these medicines for the first 2 cycles (56 days) of treatment with neratinib.

• Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

• Swallow the tablet whole. Do not crush, break, or chew it. Take it at the same time each day.

• Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

• Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

• You should start taking medicines to help prevent diarrhea (including loperamide) during your first dose of neratinib. Continue taking these medicines for the first 2 cycles (56 days) of treatment with neratinib.

• Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

• Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

• Oral routeIt is best to take this medicine with food or milk.

• Missed dose: If you miss a dose of this medicine, skip the missed dose and take your next dose at your usual time.

What to do if you miss a dose of Nerlynx

Nerlynx contraindications

• This medicine is not right for everyone. Do not use it if you had an allergic reaction to neratinib, or if you are pregnant.

Nerlynx warnings

• Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

• Tell your doctor if you have kidney disease, liver disease, low blood pressure, or dehydration.

• Do not breastfeed while you are using this medicine and for at least 1 month after your last dose.

• Oral routeMedicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

• Keep all medicine out of the reach of children. Never share your medicine with anyone.

• This medicine may cause liver problems.

• Oral routeThis medicine may cause birth defects if either partner is using it during conception or pregnancy. Tell your doctor right away if you or your partner becomes pregnant. Use an effective form of birth control during treatment with this medicine and for at least 1 month after the last dose. Male patients with female partners should use an effective form of birth control during treatment and for 3 months after the last dose.

Nerlynx interactions

• Some foods and medicines can affect how neratinib works. Tell your doctor if you are using any of the following:Aprepitant, boceprevir, bosentan, carbamazepine, ciprofloxacin, clarithromycin, clotrimazole, cobicistat, conivaptan, crizotinib, cyclosporine, dabigatran, danoprevir/ritonavir, digoxin, diltiazem, dronedarone, efavirenz, elvitegravir/ritonavir, enzalutamide, erythromycin, etravirine, fexofenadine, fluconazole, fluvoxamine, idelalisib, imatinib, indinavir/ritonavir, itraconazole, ketoconazole, lopinavir/ritonavir, mitotane, modafinil, nefazodone, nelfinavir, paritaprevir/ritonavir and (ombitasvir and/or dasabuvir), phenytoin, posaconazole, rifampin, ritonavir, saquinavir/ritonavir, St John€™s wort, tipranavir/ritonavir, tofisopam, troleandomycin, verapamil, voriconazole

• Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

• Do not take a proton pump inhibitor (including lansoprazole) together with this medicine. Ask your doctor which stomach medicines are safe for you to take.

• Take neratinib at least 2 hours before or 10 hours after an H2 blocker (including cimetidine).

• If you are also using an antacid, take it 3 hours before using neratinib.