Nitisinone is a Hereditary Tyrosinemia Type 1 (HT-1) Treatment - Agents class prescription that is produced by Par Health Usa. The typical cash price for Nitisinone is $41,200.07 per 240, 2mg capsules, but you can pay just $3,843.75 for 240, 2mg capsules with a SingleCare savings card. Nitisinone is a generic medicine; Orfadin is the brand-name variant of Nitisinone.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 02/04/2026
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Nitisinone is a Hereditary Tyrosinemia Type 1 (HT-1) Treatment - Agents class prescription that is produced by Par Health Usa. The typical cash price for Nitisinone is $41,200.07 per 240, 2mg capsules, but you can pay just $3,843.75 for 240, 2mg capsules with a SingleCare savings card. Nitisinone is a generic medicine; Orfadin is the brand-name variant of Nitisinone.
Nitisinone is a Hereditary Tyrosinemia Type 1 (HT-1) Treatment - Agents class prescription that is produced by Par Health Usa. The typical cash price for Nitisinone is $41,200.07 per 240, 2mg capsules, but you can pay just $3,843.75 for 240, 2mg capsules with a SingleCare savings card. Nitisinone is a generic medicine; Orfadin is the brand-name variant of Nitisinone.
Nitisinone costs $3,843.75 for 240, 2mg capsules with a free Nitisinone coupon from SingleCare. But, you could pay less depending on your prescription details. Use the dropdown menu above to update your Rx info (i.e., brand/generic, form, dosage, quantity) to see the most accurate prices of Nitisinone with SingleCare at a pharmacy near you.
The average out-of-pocket price of Nitisinone without health insurance is $41,200.07 per 240, 2mg capsules but you can get a discount using a SingleCare Nitisinone coupon to pay only $3,843.75 for 240, 2mg capsules of Nitisinone. People without access to insurance coverage can still use SingleCare for free Nitisinone coupons. By getting Nitisinone, you typically save money on your prescription instead of getting Orfadin - the branded form of Nitisinone, which often costs dramatically more than Nitisinone.
Every insurance formulary has different details and may or may not cover Nitisinone. The cost of Nitisinone with insurance coverage differs based on your plan - reach out to your insurance company for explicit drug coverage and coinsurance details. If your insurance does not cover Nitisinone, you can use SingleCare to save money on Nitisinone at your local pharmacies. Additionally, you can also use SingleCare savings if you have Medicare or Medicaid. When Medicare or Medicaid doesn’t offer your Nitisinone order, try SingleCare instead. Go to the SingleCare website or app to review the lowest cost of Nitisinone with SingleCare versus your Nitisinone price with insurance or Medicare.
SingleCare coupons are accepted at most major pharmacies and grocery stores, including Walgreens, Kroger, Walmart, CVS, Safeway, and more. Just text, email, print, or save your free Nitisinone coupon to your mobile wallet and show your pharmacist when you pick up your prescription.
Nitisinone is the generic form of Orfadin and is significantly cheaper than Orfadin. The SingleCare cost for Nitisinone is $3,843.75 per 240, 2mg capsules, which typically is significantly less expensive than the typical price for Orfadin but uses the same ingredients.
SingleCare is accepted at most national pharmacies and grocers, including the following:
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