Spironolactone is a potassium-sparing diuretic (water pill) that is used to treat high blood pressure, heart failure, and hyperaldosteronism (overproduction of a hormone called aldosterone). Spironolactone works by causing your body to make more urine and lose excess water. By removing excess water in the urine, Spironolactone also removes sodium and other salts from the body. However, Spironolactone reduces how much potassium is removed from the body. Spironolactone is approved by the US Food and Drug Administration (FDA). The average retail price of Spironolactone is approximately $20.55 for 30, 25mg tablets. You could pay the lowest price of $3.80 for 30, 25mg tablets of Spironolactone prescription with SingleCare’s Spironolactone coupons or prescription discount cards. We offer big savings on your prescription drugs.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 12/05/2025
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Spironolactone is a potassium-sparing diuretic (water pill) that is used to treat high blood pressure, heart failure, and hyperaldosteronism (overproduction of a hormone called aldosterone). Spironolactone works by causing your body to make more urine and lose excess water. By removing excess water in the urine, Spironolactone also removes sodium and other salts from the body. However, Spironolactone reduces how much potassium is removed from the body. Spironolactone is approved by the US Food and Drug Administration (FDA). The average retail price of Spironolactone is approximately $20.55 for 30, 25mg tablets. You could pay the lowest price of $3.80 for 30, 25mg tablets of Spironolactone prescription with SingleCare’s Spironolactone coupons or prescription discount cards. We offer big savings on your prescription drugs.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Spironolactone Retail Price | Spironolactone SingleCare Price |
|---|---|---|
| CVS Pharmacy | $16.87 | $16.85 |
| Walmart | $6.39 | $5.42 |
| Walgreens | $10.97 | $10.97 |
| Kroger Pharmacy | $15.92 | $4.20 |
| Albertsons Pharmacy | $11.10 | $5.40 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Spironolactone is a potassium-sparing diuretic (water pill) that is used to treat high blood pressure, heart failure, and hyperaldosteronism (overproduction of a hormone called aldosterone). Spironolactone works by causing your body to make more urine and lose excess water. By removing excess water in the urine, Spironolactone also removes sodium and other salts from the body. However, Spironolactone reduces how much potassium is removed from the body. Spironolactone is approved by the US Food and Drug Administration (FDA). The average retail price of Spironolactone is approximately $20.55 for 30, 25mg tablets. You could pay the lowest price of $3.80 for 30, 25mg tablets of Spironolactone prescription with SingleCare’s Spironolactone coupons or prescription discount cards. We offer big savings on your prescription drugs.
The cost of Spironolactone without insurance is approximately $20.55 for 30, 25mg tablets. To save on this price, you could use a Spironolactone coupon and pay just $3.80 for 30, 25mg tablets. Coupons can be redeemed at your local pharmacy. Check the SingleCare website to start saving right away.
The price of Spironolactone with insurance tends to vary based on the insurance plan. Most insurance plans, however, cover generic Spironolactone. Check your insurance plan’s formulary or ask your pharmacist to determine the cost of your Spironolactone prescription with insurance. To save on the cost of Spironolactone, you may be able to use a SingleCare prescription discount card. You might find that the SingleCare discount program offers a discounted price compared to the copay with your insurance.
Spironolactone is generally covered by Medicare prescription plans. The copay amount for Spironolactone will vary depending on your Medicare coverage. If you are still looking to save money on this medication, you can use a SingleCare card. When you use a SingleCare savings card, Spironolactone could cost as little as $3.80 for 30, 25mg tablets. SingleCare cards and coupons are accepted at participating pharmacies across the nation. Check the SingleCare website to find a pharmacy location near you.
Spironolactone is a generic prescription drug that is produced by various manufacturers, including Amneal Pharmaceuticals, Sun Pharma, and Zydus Pharmaceuticals. Aldactone is the brand name for Spironolactone.
Spironolactone is a diuretic that is used to treat high blood pressure, heart failure, and hyperaldosteronism (overproduction of aldosterone). It can also be used to treat edema from nephrotic syndrome, kidney problems, or liver cirrhosis. Spironolactone works by causing your body to make more urine and lose excess water. Spironolactone reduces how much potassium is removed from the body.
Spironolactone is available as a generic oral tablet in strengths of 25 mg, 50 mg, and 100 mg. It is usually taken once or twice daily. The appropriate dosage will depend on the condition being treated. Spironolactone should only be used as prescribed. Consult your doctor or pharmacist on the proper way to take Spironolactone.
The most common side effects of Spironolactone include gynecomastia (enlargement of breast tissue in males), diarrhea, nausea, vomiting, and drowsiness. Spironolactone may also cause abnormalities in menstruation, decreased libido, and erectile dysfunction. Contact your healthcare provider if side effects persist or worsen.
Serious adverse effects of Spironolactone include hyperkalemia (high potassium levels in the blood), hypotension (low blood pressure), worsened kidney function or kidney failure, and electrolyte abnormalities. Tell your healthcare professional if you have a history of hyperkalemia or Addison’s disease, or if you are taking a medication called eplerenone.
You should not use Spironolactone if you are allergic to any of its ingredients. Seek emergency medical help if you experience any of the following signs of an allergic reaction: hives, trouble breathing, or swelling of the face, lips, tongue, or throat.
In rare cases, Spironolactone can cause a life-threatening skin reaction. Get emergency medical attention right away if you have a fever, sore throat, burning eyes, red or purple rash, or blistering or peeling skin.
If you have any of the following symptoms, call your doctor right away:
Feeling lightheaded or faint
Having little or no urination
Nausea, weakness, tingling, chest pain, irregular heartbeat (these could signal high potassium levels)
Increased thirst or urination, confusion, vomiting, muscle pain, slurred speech, weakness, numbness, and incoordination (these could signal other electrolyte imbalances)
Tell your healthcare provider if you are pregnant or breastfeeding. You should also tell your doctor if you are taking other medications, such as NSAIDs, lithium, digoxin, or cholestyramine, before using Spironolactone. Consult your healthcare provider for medical advice and for more information about other possible side effects, drug interactions, warnings, and precautions with Spironolactone.
Store Spironolactone at room temperature, away from direct light, heat, and moisture. Do not store it in the bathroom. Keep out of reach and out of sight of children and pets.
After receiving her doctorate from the University of Pittsburgh School of Pharmacy, Karen Berger, Pharm.D., has worked in both chain and independent community pharmacies. She currently works at an independent pharmacy in New Jersey. Dr. Berger enjoys helping patients understand medical conditions and medications—both in person as a pharmacist, and online as a medical writer and reviewer.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved