What is Nitro-Time: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Nitro-Time overview

BRAND NAMES:

  • Nitro-Time, Nitrostat, Nitro-Time

Generic Names:

  • Nitro-Time

Uses:

  • Treats or prevents angina (chest pain). This medicine is a nitrate.

Therapeutic Classes:

  • Antianginal, Coronary Vasodilator

Forms:

  • Long Acting Capsule, Tablet, Long Acting Tablet

How it’s taken:

  • By mouth

What is Nitro-Time used for?

Nitroglycerin ER belongs to a class of drugs known as nitrates. It is used to prevent chest pain or angina in people with coronary artery disease. Nitroglycerin ER works by relaxing and widening blood vessels so blood can flow more easily to the heart.

What form(s) does Nitro-Time come in

  • Long Acting Capsule

  • Tablet

  • Long Acting Tablet

What are common Nitro-Time doses?

  • Capsule 2.5mg

  • Capsule 6.5mg

  • Capsule 9mg

Common Nitro-Time prescriptions

  • Nitro-Time
    2.5mg capsule

  • Nitro-Time
    6.5mg capsule

  • Nitro-Time
    9mg capsule

How to take Nitro-Time

  • Your doctor will tell you how much medicine to use. Do not use more than directed. Sit down before you take this medicine, because it could make you lightheaded.

  • Most people use this medicine for only part of the day or as needed.

  • Extended-release capsule or extended-release tablet: Take on an empty stomach with a full glass of water.Swallow whole. Do not crush, break, or chew it.

  • Buccal tablet: Place it between your gum and upper cheek or upper lip. Let the tablet dissolve slowly in your mouth over several hours. Do not chew, crush, or swallow the tablet or put it under your tongue. Avoid drinking anything hot while the tablet is in your mouth and do not touch the tablet with your tongue.Do not go to sleep with a buccal tablet in your mouth.

  • Sublingual tablet:Wet the tablet with saliva and place it under your tongue or inside your cheek. Let the tablet dissolve. Do not chew, crush, or swallow the tablet. Wait 5 minutes. If you still have pain, take a second tablet. Do not take more than 3 tablets in 15 minutes. If you still have pain after you take a total of 3 tablets, this is an emergency. Call 911. Do not drive yourself to the hospital.You may use this medicine 5 to 10 minutes before an activity that can cause angina. This may help prevent the attack.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Store the sublingual tablets at room temperature in the original glass container, away from heat, moisture, and direct light.

  • Extended-release capsule or extended-release tablet: Take on an empty stomach with a full glass of water.Swallow whole. Do not crush, break, or chew it.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Sublingual tablet:Wet the tablet with saliva and place it under your tongue or inside your cheek. Let the tablet dissolve. Do not chew, crush, or swallow the tablet. Wait 5 minutes. If you still have pain, take a second tablet. Do not take more than 3 tablets in 15 minutes. If you still have pain after you take a total of 3 tablets, this is an emergency. Call 911. Do not drive yourself to the hospital.You may use this medicine 5 to 10 minutes before an activity that can cause angina. This may help prevent the attack.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Store the sublingual tablets at room temperature in the original glass container, away from heat, moisture, and direct light.

  • Buccal tablet: Place it between your gum and upper cheek or upper lip. Let the tablet dissolve slowly in your mouth over several hours. Do not chew, crush, or swallow the tablet or put it under your tongue. Avoid drinking anything hot while the tablet is in your mouth and do not touch the tablet with your tongue.Do not go to sleep with a buccal tablet in your mouth.

  • Your doctor will tell you how much medicine to use. Do not use more than directed. Sit down before you take this medicine, because it could make you lightheaded.

  • Most people use this medicine for only part of the day or as needed.

What to do if you miss a dose of Nitro-Time

  • Store the medicine at room temperature in a closed container, away from heat, moisture, and direct light. Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.

  • Keep all medicine out of the reach of children and never share your medicine with anyone.

Nitro-Time contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to nitroglycerin or similar medicines.

Nitro-Time warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, anemia, congestive heart failure, enlarged heart, low blood pressure, or a recent heart attack. Tell your doctor if you have a history of a head injury.

  • This medicine may make you dizzy or lightheaded. Do not drive or do anything else that could be dangerous until you know how this medicine affects you. These symptoms may be worse if you drink alcohol.

  • Medicines that treat chest pain sometimes cause headaches when you first start using it. This is normal. Do not stop using the medicine or change the time you use it to avoid headaches. Ask your doctor if you can take aspirin or acetaminophen to treat the headache.

  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Throbbing, severe, or ongoing headache, confusion, low fever, or trouble seeing

Nitro-Time interactions

  • Do not use this medicine if you are also using avanafil, riociguat, sildenafil, tadalafil, or vardenafil.

  • Some medicines can affect how nitroglycerin works. Tell your doctor if you are using any of the following:Alteplase, aspirin, heparinBlood pressure medicineDiuretic (water pill)Ergot medicine

  • Tell your doctor if you are using any medicine that makes your mouth dry, such as medicines that treat depression.

  • Do not drink alcohol while you are using this medicine.

Nitro-Time side effects

Serious Side Effects

  • Blurred vision, dry mouth

  • Increased chest pain, fast or slow heartbeat

  • Trouble breathing, cold sweat, blue skin, lips, or nails

  • Throbbing, severe, or ongoing headache, confusion, low fever, or trouble seeing

  • Severe or ongoing dizziness, lightheadedness, or fainting

  • Warmth or redness in your face, neck, arms, or upper chest

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

Less Serious Side Effects

  • Nausea, vomiting, weakness

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