What is Nuzyra? Uses, warnings & side effects

Updated May 14, 2025  •  Published Dec 30, 2020

Nuzyra overview

BRAND NAMES:

  • Nuzyra, Nuzyra

Generic Names:

  • Nuzyra

Uses:

  • Treats community-acquired pneumonia and acute bacterial skin and skin structure infections (ABSSSI). This medicine is a tetracycline antibiotic., Treats community-acquired pneumonia and acute bacterial skin and skin structure infections (ABSSSI). This medicine is a tetracycline antibiotic.

Therapeutic Classes:

  • Antibacterial, Antibacterial

Forms:

  • Tablet, Injectable

How it’s taken:

  • By injection, By mouth

What is Nuzyra used for?

What form(s) does Nuzyra come in?

  • Tablet

  • Injectable

What are common Nuzyra dosages?

  • Tablet 150MG

Nuzyra images - What does Nuzyra look like?

  • Nuzyra
    100mg solution reconstituted

  • Nuzyra
    150mg tablet

How to take Nuzyra

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein. The medicine must be given slowly, so the needle will have to remain in place for at least 30 minutes.

  • Injection routeA nurse or other health provider will give you this medicine.

  • Missed dose: You must use this medicine on a fixed schedule. Call your doctor or pharmacist if you miss a dose.

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein. The medicine must be given slowly, so the needle will have to remain in place for at least 30 minutes.

  • Injection routeA nurse or other health provider will give you this medicine.

  • Missed dose: You must use this medicine on a fixed schedule. Call your doctor or pharmacist if you miss a dose.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Do not eat or drink (except water) 4 hours before and 2 hours after using this medicine.

  • Take all of the medicine in your prescription to clear up your infection, even if you feel better after the first few doses.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Do not eat or drink (except water) 4 hours before and 2 hours after using this medicine.

  • Take all of the medicine in your prescription to clear up your infection, even if you feel better after the first few doses.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

What to do if you miss a dose of Nuzyra

Nuzyra contraindications - Who shouldn't take Nuzyra?

  • This medicine is not right for everyone. You should not receive it if you had an allergic reaction to omadacycline or similar medicines, or if you are pregnant or breastfeeding.

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to omadacycline or similar medicines, or if you are pregnant or breastfeeding.

Nuzyra warnings

  • It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.

  • Do not breastfeed during treatment with this medicine and for 4 days after the last dose.

  • Tell your doctor if you have diarrhea or eye or vision problems.

  • This medicine may cause the following problems:Slow bone growth or permanent change in tooth color (in children 8 years of age and younger)Increased pressure inside the head

  • This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine.

  • This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds.

  • Call your doctor if your symptoms do not improve or if they get worse.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.

  • Do not breastfeed during treatment with this medicine and for 4 days after the last dose.

  • Tell your doctor if you have diarrhea or eye or vision problems.

  • This medicine may cause the following problems:Slow bone growth or permanent change in tooth color (in children 8 years of age and younger)Increased pressure inside the head

  • This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine.

  • This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds.

  • Call your doctor if your symptoms do not improve or if they get worse.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Nuzyra interactions & what to avoid when taking Nuzyra

  • Some foods and medicines can affect how omadacycline works. Tell your doctor if you are using a blood thinner (including warfarin).

  • Do not eat dairy products or take antacids or multivitamins (containing aluminum, calcium, magnesium, bismuth subsalicylate, or iron) for 4 hours after using this medicine.

  • Some medicines can affect how omadacycline works. Tell your doctor if you are using a blood thinner (including warfarin).

Nuzyra side effects - How does Nuzyra make you feel?

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Blurred vision or other change in vision

  • Changes in the amount or frequency of urination, bloody or cloudy urine, lower back or side pain

  • Increased sensitivity of the skin to sunlight, severe sunburn or skin rash

  • Severe diarrhea that is watery or bloody

  • Severe headache, dizziness

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Blurred vision or other change in vision

  • Changes in the amount or frequency of urination, bloody or cloudy urine, lower back or side pain

  • Increased sensitivity of the skin to sunlight, severe sunburn or skin rash

  • Severe diarrhea that is watery or bloody

  • Severe headache, dizziness

Less Serious Side Effects

  • Nausea, vomiting

  • Pain, itching, burning, swelling, or a lump under your skin where the needle is placed

  • Nausea, vomiting

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