Enbrel Sureclick is a brand-name prescription drug distributed in a pre-filled injection pen so that patients can self-inject the drug. Enbrel is used to treat active rheumatoid arthritis, psoriatic arthritis, juvenile idiopathic arthritis, Kawasaki disease, and plaque psoriasis. In all these conditions, the body's immune system “misfires” and attacks healthy tissues in the joints, skin, or blood vessels, causing swelling, stiffness, and pain. The active ingredient in Enbrel Sureclick, etanercept, suppresses the immune system and so reduces the body's attack on the joints. Enbrel Sureclick costs $10,305.16 for 4, 1ml of 50mg/ml pen of Enbrel Sureclick at full price. A SingleCare Enbrel Sureclick coupon reduces that price to $7,709.52.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 09/17/2026
Enbrel Sureclick is a brand-name prescription drug distributed in a pre-filled injection pen so that patients can self-inject the drug. Enbrel is used to treat active rheumatoid arthritis, psoriatic arthritis, juvenile idiopathic arthritis, Kawasaki disease, and plaque psoriasis. In all these conditions, the body's immune system “misfires” and attacks healthy tissues in the joints, skin, or blood vessels, causing swelling, stiffness, and pain. The active ingredient in Enbrel Sureclick, etanercept, suppresses the immune system and so reduces the body's attack on the joints. Enbrel Sureclick costs $10,305.16 for 4, 1ml of 50mg/ml pen of Enbrel Sureclick at full price. A SingleCare Enbrel Sureclick coupon reduces that price to $7,709.52.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Enbrel Sureclick Retail Price | Enbrel Sureclick SingleCare Price |
|---|---|---|
| Walmart | $10278.60 | $9529.28 |
| Walgreens | $10288.88 | $8047.96 |
| Kroger Pharmacy | $10278.48 | $7712.52 |
| Albertsons Pharmacy | $11344.68 | $8300.36 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Enbrel Sureclick is a brand-name prescription drug distributed in a pre-filled injection pen so that patients can self-inject the drug. Enbrel is used to treat active rheumatoid arthritis, psoriatic arthritis, juvenile idiopathic arthritis, Kawasaki disease, and plaque psoriasis. In all these conditions, the body's immune system “misfires” and attacks healthy tissues in the joints, skin, or blood vessels, causing swelling, stiffness, and pain. The active ingredient in Enbrel Sureclick, etanercept, suppresses the immune system and so reduces the body's attack on the joints. Enbrel Sureclick costs $10,305.16 for 4, 1ml of 50mg/ml pen of Enbrel Sureclick at full price. A SingleCare Enbrel Sureclick coupon reduces that price to $7,709.52.
Enbrel Sureclick costs $7,709.52 for 4, 1ml of 50mg/ml pens with a free Enbrel Sureclick coupon from SingleCare. However, you could pay less depending on your prescription information. Use the dropdown menu above to enter your Rx info (i.e., generic/brand, quantity, dosage, form) to get the most accurate prices of Enbrel Sureclick with SingleCare near you.
At most pharmacies, the full cost of Enbrel Sureclick will be $10,305.16 for 4, 1ml of 50mg/ml pen of Enbrel Sureclick. That same prescription will cost $7,709.52 using a SingleCare savings card, which you can use at major pharmacies throughout the country.
The copay cost of Enbrel Sureclick varies greatly depending on your insurance plan and could be very high. With SingleCare, Enbrel Sureclick costs only $7,709.52 for 4, 1ml of 50mg/ml pens of Enbrel Sureclick. Ask your pharmacist to compare that SingleCare cost to your copay so that you get the best deal on your prescription.
Medicare Advantage and Medicare Part D prescription drug insurance plans usually provide coverage for Enbrel Sureclick. If you don't have Medicare coverage, consider using a SingleCare Enbrel Sureclick coupon for your prescription. With SingleCare, the price of Enbrel Sureclick is $7,709.52 for 4, 1ml of 50mg/ml pens.
Enbrel Sureclick is a brand-name prescription drug with the active ingredient etanercept. Because Enbrel Sureclick is a complex biologic medication made from living cells, it does not have a traditional generic. However, there are FDA-approved "biosimilars", such as Erelzi and Eticovo, which are highly similar to Enbrel and work in the same way. But due to patent restrictions these biosimilars are not expected to become widely available until around 2029.
Enbrel Sureclick is a brand-name prescription drug, Enbrel, packaged as pre-filled pen injectors. Historically, Enbrel was packaged in vials or syringes and injected by a healthcare professional, but Enbrel Sureclick can now be purchased in a pharmacy and self-injected by the patient using a special device. The SureClick device is an auto-injector pen with a hidden needle that delivers a dose with a single button push, making it easier for patients with limited hand movement or joint pain to use than a standard syringe.
Enbrel is used to treat active rheumatoid arthritis, psoriatic arthritis, juvenile idiopathic arthritis, Kawasaki disease, and psoriasis, a condition in which skin cells grow ten times faster than normal and build up into dry, scaly patches. All these conditions are caused when the body's immune system “overreacts” and starts attacking healthy tissues as if they were infections, causing swelling, stiffness, and pain.
The active ingredient in Enbrel Sureclick, etanercept interferes with a particular chemical called Tumor Necrosis Factor, which “signals” the immune system to release substances that cause swelling in the joints or the skin. The effect is to calm the immune system and relieve the swelling, stiffness, and pain associated with these chronic conditions.
Enbrel Sureclick suppresses the immune system and sometimes lowers white blood cell counts, the first line of defense against infections. So Enbrel Sureclick lowers the body's ability to prevent or fight infections, putting patients at a higher risk of contracting severe and life-threatening infections. Patients with active infections, particularly hepatitis B, should not take Enbrel Sureclick unless approved by the prescribing physician. Immune suppression also increases the risk of certain types of cancer, such as lymphoma, especially in children and adolescents.
The most commonly experienced side effects are infections of various kinds and injection site reactions, such as redness, swelling, discomfort, and a lump where the injection was made. These injection site reactions typically fade in a day or two, while infections require antibiotic treatments to resolve.
Other side effects include mild nausea, vomiting, diarrhea, headache, stomach pain, indigestion, weight changes, cold symptoms, weakness, seizures, bleeding, heart failure, and liver problems. Enbrel Sureclick may cause mood changes, especially in children.
Allergic reactions are rare but can be severe and include lupus-type syndromes.
This is not a complete list of possible side effects. Consult with your prescribing physician and pharmacist about possible side effects before starting on Enbrel Sureclick.
You can use SingleCare coupons at most major pharmacies and grocery stores, including Walgreens, Kroger, Walmart, CVS, Safeway, and more. Just text, email, print, or save your free Enbrel Sureclick coupon to your digital wallet and show a pharmacist at checkout.
Jeff Fortner, Pharm.D., focuses his practice and research on pharmaceutical compounding, patient-centered care in the community setting, and pharmacist-provided clinical services. He maintains a practice site at an independent community pharmacy that also specializes in non-sterile compounding and long-term care medication preparation. Dr. Fortner enjoys spending time with his wife and two young daughters, trying and sharing new craft beers, reading sci-fi/fantasy fiction, and cycling.
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SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2026 SingleCare Administrators. All rights reserved