Enbrel Sureclick Coupons & Prices

Enbrel Sureclick is a brand-name prescription drug distributed in a pre-filled injection pen so that patients can self-inject the drug. Enbrel is used to treat active rheumatoid arthritis, psoriatic arthritis, juvenile idiopathic arthritis, Kawasaki disease, and plaque psoriasis. In all these conditions, the body's immune system “misfires” and attacks healthy tissues in the joints, skin, or blood vessels, causing swelling, stiffness, and pain. The active ingredient in Enbrel Sureclick, etanercept, suppresses the immune system and so reduces the body's attack on the joints. Enbrel Sureclick costs $10,305.16 for 4, 1ml of 50mg/ml pen of Enbrel Sureclick at full price. A SingleCare Enbrel Sureclick coupon reduces that price to $7,709.52.

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Enbrel Sureclick coupon at Kroger Pharmacy
$7712.52
$ 7,710
$3 off with signupwith signup

Show this free card to your pharmacist.

This coupon is not insurance.
Enbrel Sureclick coupon at Harris Teeter Pharmacy
$7712.52
$ 7,710
$3 off with signupwith signup
Enbrel Sureclick coupon at Publix Pharmacy
$8098.29
$ 8,095
$3 off with signupwith signup
Enbrel Sureclick coupon at Walgreens Pharmacy
$8148.43
$ 8,145
$3 off with signupwith signup
Enbrel Sureclick coupon at Costco Pharmacy
$8300.86
$ 8,298
$3 off with signupwith signup

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 09/17/2026

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About Enbrel Sureclick

Enbrel Sureclick is a brand-name prescription drug distributed in a pre-filled injection pen so that patients can self-inject the drug. Enbrel is used to treat active rheumatoid arthritis, psoriatic arthritis, juvenile idiopathic arthritis, Kawasaki disease, and plaque psoriasis. In all these conditions, the body's immune system “misfires” and attacks healthy tissues in the joints, skin, or blood vessels, causing swelling, stiffness, and pain. The active ingredient in Enbrel Sureclick, etanercept, suppresses the immune system and so reduces the body's attack on the joints. Enbrel Sureclick costs $10,305.16 for 4, 1ml of 50mg/ml pen of Enbrel Sureclick at full price. A SingleCare Enbrel Sureclick coupon reduces that price to $7,709.52.

Enbrel Sureclick Price History & Information

Price History for Enbrel Sureclick

4 count, Syringe, 0.98ml of 50mg/ml

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 1-Month Prices for Enbrel Sureclick

4 count, Syringe, 0.98ml of 50mg/ml
PharmacyEnbrel Sureclick Retail PriceEnbrel Sureclick SingleCare Price
Walmart$10278.60$9529.28
Walgreens$10288.88$8047.96
Kroger Pharmacy$10278.48$7712.52
Albertsons Pharmacy$11344.68$8300.36

These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Enbrel Sureclick

Enbrel Sureclick is a brand-name prescription drug distributed in a pre-filled injection pen so that patients can self-inject the drug. Enbrel is used to treat active rheumatoid arthritis, psoriatic arthritis, juvenile idiopathic arthritis, Kawasaki disease, and plaque psoriasis. In all these conditions, the body's immune system “misfires” and attacks healthy tissues in the joints, skin, or blood vessels, causing swelling, stiffness, and pain. The active ingredient in Enbrel Sureclick, etanercept, suppresses the immune system and so reduces the body's attack on the joints. Enbrel Sureclick costs $10,305.16 for 4, 1ml of 50mg/ml pen of Enbrel Sureclick at full price. A SingleCare Enbrel Sureclick coupon reduces that price to $7,709.52.

Enbrel Sureclick FAQs

Medically reviewed by Jeff FortnerPharm.D.
Licensed Pharmacist

How much is Enbrel Sureclick with SingleCare?

Enbrel Sureclick costs $7,709.52 for 4, 1ml of 50mg/ml pens with a free Enbrel Sureclick coupon from SingleCare.  However, you could pay less depending on your prescription information. Use the dropdown menu above to enter your Rx info (i.e., generic/brand, quantity, dosage, form) to get the most accurate prices of Enbrel Sureclick with SingleCare near you.

How much does Enbrel Sureclick cost without insurance?

At most pharmacies, the full cost of Enbrel Sureclick will be $10,305.16 for 4, 1ml of 50mg/ml pen of Enbrel Sureclick. That same prescription will cost $7,709.52 using a SingleCare savings card, which you can use at major pharmacies throughout the country.

How much does Enbrel Sureclick cost with insurance?

The copay cost of Enbrel Sureclick varies greatly depending on your insurance plan and could be very high. With SingleCare, Enbrel Sureclick costs only $7,709.52 for 4, 1ml of 50mg/ml pens of Enbrel Sureclick. Ask your pharmacist to compare that SingleCare cost to your copay so that you get the best deal on your prescription.

Does Medicare cover Enbrel Sureclick and how much does it cost?

Medicare Advantage and Medicare Part D prescription drug insurance plans usually provide coverage for Enbrel Sureclick. If you don't have Medicare coverage, consider using a SingleCare Enbrel Sureclick coupon for your prescription. With SingleCare, the price of Enbrel Sureclick is $7,709.52 for 4, 1ml of 50mg/ml pens.

Is there a generic of Enbrel Sureclick?

Enbrel Sureclick is a brand-name prescription drug with the active ingredient etanercept. Because Enbrel Sureclick is a complex biologic medication made from living cells, it does not have a traditional generic. However, there are FDA-approved "biosimilars", such as Erelzi and Eticovo, which are highly similar to Enbrel and work in the same way. But due to patent restrictions these biosimilars are not expected to become widely available until around 2029.

What is Enbrel Sureclick?

Enbrel Sureclick is a brand-name prescription drug, Enbrel, packaged as pre-filled pen injectors. Historically, Enbrel was packaged in vials or syringes and injected by a healthcare professional, but Enbrel Sureclick can now be purchased in a pharmacy and self-injected by the patient using a special device. The SureClick device is an auto-injector pen with a hidden needle that delivers a dose with a single button push, making it easier for patients with limited hand movement or joint pain to use than a standard syringe.

Enbrel is used to treat active rheumatoid arthritis, psoriatic arthritis, juvenile idiopathic arthritis, Kawasaki disease, and psoriasis, a condition in which skin cells grow ten times faster than normal and build up into dry, scaly patches. All these conditions are caused when the body's immune system “overreacts” and starts attacking healthy tissues as if they were infections, causing swelling, stiffness, and pain.

The active ingredient in Enbrel Sureclick, etanercept interferes with a particular chemical called Tumor Necrosis Factor, which “signals” the immune system to release substances that cause swelling in the joints or the skin. The effect is to calm the immune system and relieve the swelling, stiffness, and pain associated with these chronic conditions.

What are the side effects of Enbrel Sureclick?

Enbrel Sureclick suppresses the immune system and sometimes lowers white blood cell counts, the first line of defense against infections. So Enbrel Sureclick lowers the body's ability to prevent or fight infections, putting patients at a higher risk of contracting severe and life-threatening infections. Patients with active infections, particularly hepatitis B, should not take Enbrel Sureclick unless approved by the prescribing physician. Immune suppression also increases the risk of certain types of cancer, such as lymphoma, especially in children and adolescents.

The most commonly experienced side effects are infections of various kinds and injection site reactions, such as redness, swelling, discomfort, and a lump where the injection was made. These injection site reactions typically fade in a day or two, while infections require antibiotic treatments to resolve.

Other side effects include mild nausea, vomiting, diarrhea, headache, stomach pain, indigestion, weight changes, cold symptoms, weakness, seizures, bleeding, heart failure, and liver problems. Enbrel Sureclick may cause mood changes, especially in children.

Allergic reactions are rare but can be severe and include lupus-type syndromes.

This is not a complete list of possible side effects. Consult with your prescribing physician and pharmacist about possible side effects before starting on Enbrel Sureclick.

How to use SingleCare for Enbrel Sureclick

You can use SingleCare coupons at most major pharmacies and grocery stores, including Walgreens, Kroger, Walmart, CVS, Safeway, and more. Just text, email, print, or save your free Enbrel Sureclick coupon to your digital wallet and show a pharmacist at checkout. 

Medically reviewed by Jeff FortnerPharm.D.
Licensed Pharmacist

Jeff Fortner, Pharm.D., focuses his practice and research on pharmaceutical compounding, patient-centered care in the community setting, and pharmacist-provided clinical services. He maintains a practice site at an independent community pharmacy that also specializes in non-sterile compounding and long-term care medication preparation. Dr. Fortner enjoys spending time with his wife and two young daughters, trying and sharing new craft beers, reading sci-fi/fantasy fiction, and cycling.

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Where are Enbrel Sureclick coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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