Pain Relief is the use of medications or medical devices to help relieve or manage acute or chronic pain. Some Pain Relief medications and medical devices can be purchased over-the-counter, while others are available only with a prescription. Pain Relief medications come in several types: non-steroidal anti-inflammatory drugs (NSAIDs), acetaminophen, counter-irritants, anesthetics, corticosteroids, and opioids. Drugs from other classes, such as antidepressants, anxiety medications, and anticonvulsants are sometimes used to treat chronic pain. Medical devices, particularly heat, cold, and vibration devices, have always been a major pillar in managing pain. Recent years have seen the introduction of more advanced technologies including laser, ultrasound, electricity, and electromagnetic pulses. The cost of Pain Relief can vary widely depending on the type, brand, and quantity but you can save up to 80% with a SingleCare savings card. Our lowest price for Pain Relief is $8.63. Our FAQs section below has much more information about Pain Relief, how Pain Relief medications and medical devices work, possible side effects, how you can save money on Pain Relief, and how to find SingleCare Pain Relief coupons for the product you need.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 05/05/2026
Pain Relief is the use of medications or medical devices to help relieve or manage acute or chronic pain. Some Pain Relief medications and medical devices can be purchased over-the-counter, while others are available only with a prescription. Pain Relief medications come in several types: non-steroidal anti-inflammatory drugs (NSAIDs), acetaminophen, counter-irritants, anesthetics, corticosteroids, and opioids. Drugs from other classes, such as antidepressants, anxiety medications, and anticonvulsants are sometimes used to treat chronic pain. Medical devices, particularly heat, cold, and vibration devices, have always been a major pillar in managing pain. Recent years have seen the introduction of more advanced technologies including laser, ultrasound, electricity, and electromagnetic pulses. The cost of Pain Relief can vary widely depending on the type, brand, and quantity but you can save up to 80% with a SingleCare savings card. Our lowest price for Pain Relief is $8.63. Our FAQs section below has much more information about Pain Relief, how Pain Relief medications and medical devices work, possible side effects, how you can save money on Pain Relief, and how to find SingleCare Pain Relief coupons for the product you need.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Acetaminophen Extra Strength Retail Price | Acetaminophen Extra Strength SingleCare Price |
|---|---|---|
| Kroger Pharmacy | $0.75 | $0.75 |
| Albertsons Pharmacy | $1.20 | $1.20 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Pain Relief is the use of medications or medical devices to help relieve or manage acute or chronic pain. Some Pain Relief medications and medical devices can be purchased over-the-counter, while others are available only with a prescription. Pain Relief medications come in several types: non-steroidal anti-inflammatory drugs (NSAIDs), acetaminophen, counter-irritants, anesthetics, corticosteroids, and opioids. Drugs from other classes, such as antidepressants, anxiety medications, and anticonvulsants are sometimes used to treat chronic pain. Medical devices, particularly heat, cold, and vibration devices, have always been a major pillar in managing pain. Recent years have seen the introduction of more advanced technologies including laser, ultrasound, electricity, and electromagnetic pulses. The cost of Pain Relief can vary widely depending on the type, brand, and quantity but you can save up to 80% with a SingleCare savings card. Our lowest price for Pain Relief is $8.63. Our FAQs section below has much more information about Pain Relief, how Pain Relief medications and medical devices work, possible side effects, how you can save money on Pain Relief, and how to find SingleCare Pain Relief coupons for the product you need.
Both over-the-counter and prescription Pain Relief medication and medical device prices will vary depending on type, brand, ingredients, dosage, and retailer. You can save as much as 80% on prescription Pain Relief medications and medical devices with a SingleCare Pain Relief coupon. Also, SingleCare discounts are available on over-the-counter products, like over-the-counter Pain Relief medications or devices, when prescribed by a physician. SingleCare is accepted at many nationwide pharmacies and retailers: CVS, Target, Long Drugs, Walmart, and many others.
Insurance copays for prescription Pain Relief medications or medical devices will depend on your prescription and insurance plan. SingleCare can be a trustworthy way to save money even in comparison with insurance copays. To get the best price on Pain Relief, compare your insurance copay to SingleCare’s discount.
Medicare insurance coverage on Pain Relief depends on the prescription and insurance plan. However, your copay cost will vary according to your plan, so it's a good idea to compare prices with your pharmacist. You will reliably save money with SingleCare savings card, and your savings may be better than your Medicare copays. SingleCare is accepted at large retailers, like Walmart, drugstores, like Walgreens, and supermarket pharmacies, like Harris Teeter.
Many prescription and over-the-counter Pain Relief medications and basic medical devices have generic versions at a lower price. Search the SingleCare website or app for the Pain Relief you need to find generic alternatives and coupons that could cut your Pain Relief costs by up to 80%.
Pain Relief is the medical or home management of temporary (acute) or long-term (chronic) pain through medications, medical devices, therapy, or a combination of all three.
There are six main categories of Pain Relief medications available both with or without a prescription: NSAIDs, acetaminophen, counter-irritants, anesthetics, corticosteroids, and opioids. Other medications, such as antidepressants, anxiolytics (anti-anxiety medications), and anticonvulsants are sometimes prescribed for pain management. Many of these medications are classified as analgesics, that is, they relieve pain. Anesthetics, on the other hand, partially or totally remove the sensation of pain by numbing the nerves. Other medications have no analgesic or anesthetic properties.
Non-steroidal anti-inflammatory drugs (NSAIDs) are the most commonly used pain medication both with and without a prescription. These analgesic drugs, which include aspirin and ibuprofen, block the body's production of prostaglandins, substances that cause swelling, and fever.
Acetaminophen is another common over-the-counter and prescription-only analgesic that stands in a class on its own. Acetaminophen works similarly to NSAIDs but does not reduce swelling.
Counter-irritants are very common as over-the-counter pain relief medications. Neither analgesic, or anesthetic, these drugs work on the principle of the gate theory of pain: providing a surplus of non-pain signals “drowns out” pain signals. Counter-irritants are common in topical pain relief medications as well as cough and sore throat medicines and include capsaicin, menthol, eucalyptus, methyl salicylate, and camphor.
Anesthetics, such as lidocaine, numb the nerves and prevent nerve signals from getting produced or sent. They are used for the temporary relief of pain. Over-the-counter anesthetics are common in topical medications, such as Aspercreme (lidocaine) and Orajel (benzocaine), and are used to relieve pain and discomfort on the skin or in the mouth. Prescription anesthetics are commonly used in medical and dental procedures and some, like propofol, may also produce sleep (sedation).
Corticosteroids are the second-most prescribed Pain Relief medication for pain relief. Corticosteroids, such as cortisone, are anti-inflammatory drugs, not analgesics, but they provide fast-acting and long-lasting pain relief by dramatically reducing the swelling that causes pain. Some corticosteroids, such as hydrocortisone, are available over-the-counter in topical medications to treat skin discomfort and pain.
Opioids and opioid-like drugs are the most controlled analgesics but are commonly prescribed for both temporary and chronic pain. These drugs act by attaching to receptors in nerve cells and block certain nerve signals, including pain signals. These drugs, which include opium, morphine, codeine, and tramadol, are highly effective at reducing and even eliminating moderate to severe pain. Their effectiveness wears off within a couple of weeks as patients develop tolerance, so they are usually prescribed only for the short-term relief of pain.
Antidepressants provide moderate chronic pain relief by changing the chemistry of the central nervous system. The effects take one or two weeks to be evident. Anti-anxiety medications interfere with the chemicals that cause muscles to contract, so they help relieve muscle tension and muscle spasms that may be the cause of chronic pain. Finally, anticonvulsants slow down nerve signals and have been found to effectively treat nerve pain, such as that induced by carpal tunnel syndrome.
The most common and reliable medical devices for relieving pain involve applying heat, ice, or vibration. All of these medical devices work primarily on the gate theory of pain management – overwhelming the nervous system with other input to “drown out” the pain signals. Heat and ice also help to relieve swelling, and vibration devices help to loosen muscles and decrease muscle spasms.
A new generation of Pain Relief medical devices involve stimulating nerves, relaxing muscles, changing nerve chemistry, or overwhelming the nerves with other input using electromagnetism, electricity, lasers, and ultrasound. Many of these are wearable devices that can be used throughout the day in different contests.
Each specific formulation will have different remedial or curative effects. Search our website or app for the Pain Relief brand or name to find out more about that remedy: what it is, how it works, possible side effects, how much it costs, and how you can save money.
Side effects will vary depending on the product and the underlying condition. Search our website or app for a specific Pain Relief brand or name to learn more about the possible side effects.
SingleCare is accepted at most national pharmacies and grocers, including the following:
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SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
© 2026 SingleCare Administrators. All rights reserved
© 2026 SingleCare Administrators. All rights reserved