Pain Relief Coupons & Prices

Acetaminophen Extra Strength

Pain Relief is the use of medications or medical devices to help relieve or manage acute or chronic pain. Some Pain Relief medications and medical devices can be purchased over-the-counter, while others are available only with a prescription. Pain Relief medications come in several types: non-steroidal anti-inflammatory drugs (NSAIDs), acetaminophen, counter-irritants, anesthetics, corticosteroids, and opioids. Drugs from other classes, such as antidepressants, anxiety medications, and anticonvulsants are sometimes used to treat chronic pain. Medical devices, particularly heat, cold, and vibration devices, have always been a major pillar in managing pain. Recent years have seen the introduction of more advanced technologies including laser, ultrasound, electricity, and electromagnetic pulses. The cost of Pain Relief can vary widely depending on the type, brand, and quantity but you can save up to 80% with a SingleCare savings card. Our lowest price for Pain Relief is $8.38. Our FAQs section below has much more information about Pain Relief, how Pain Relief medications and medical devices work, possible side effects, how you can save money on Pain Relief, and how to find SingleCare Pain Relief coupons for the product you need.

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Pain Relief coupon at Publix Pharmacy
$ 8.38

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Pain Relief coupon at Food Lion Pharmacy
$ 8.63

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Pain Relief coupon at Kroger Pharmacy
$12.34
$ 9.34
$3 off with signupwith signup
Pain Relief coupon at Harris Teeter Pharmacy
$12.34
$ 9.34
$3 off with signupwith signup
Pain Relief coupon at Costco Pharmacy
$ 10.63
Pain Relief coupon at Walgreens Pharmacy
$19.48
$ 16.48
$3 off with signupwith signup

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 12/05/2025

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About Pain Relief

Pain Relief is the use of medications or medical devices to help relieve or manage acute or chronic pain. Some Pain Relief medications and medical devices can be purchased over-the-counter, while others are available only with a prescription. Pain Relief medications come in several types: non-steroidal anti-inflammatory drugs (NSAIDs), acetaminophen, counter-irritants, anesthetics, corticosteroids, and opioids. Drugs from other classes, such as antidepressants, anxiety medications, and anticonvulsants are sometimes used to treat chronic pain. Medical devices, particularly heat, cold, and vibration devices, have always been a major pillar in managing pain. Recent years have seen the introduction of more advanced technologies including laser, ultrasound, electricity, and electromagnetic pulses. The cost of Pain Relief can vary widely depending on the type, brand, and quantity but you can save up to 80% with a SingleCare savings card. Our lowest price for Pain Relief is $8.38. Our FAQs section below has much more information about Pain Relief, how Pain Relief medications and medical devices work, possible side effects, how you can save money on Pain Relief, and how to find SingleCare Pain Relief coupons for the product you need.

Pain Relief Price History & Information

Price History for Pain Relief (Branded Generic) & Acetaminophen Extra Strength (Generic)

30 count, liquid (quantity in ml), 500mg/15ml

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 1-Month Prices for Pain Relief (Branded Generic) & Acetaminophen Extra Strength (Generic)

30 count, liquid (quantity in ml), 500mg/15ml

These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Pain Relief

Pain Relief is the use of medications or medical devices to help relieve or manage acute or chronic pain. Some Pain Relief medications and medical devices can be purchased over-the-counter, while others are available only with a prescription. Pain Relief medications come in several types: non-steroidal anti-inflammatory drugs (NSAIDs), acetaminophen, counter-irritants, anesthetics, corticosteroids, and opioids. Drugs from other classes, such as antidepressants, anxiety medications, and anticonvulsants are sometimes used to treat chronic pain. Medical devices, particularly heat, cold, and vibration devices, have always been a major pillar in managing pain. Recent years have seen the introduction of more advanced technologies including laser, ultrasound, electricity, and electromagnetic pulses. The cost of Pain Relief can vary widely depending on the type, brand, and quantity but you can save up to 80% with a SingleCare savings card. Our lowest price for Pain Relief is $8.38. Our FAQs section below has much more information about Pain Relief, how Pain Relief medications and medical devices work, possible side effects, how you can save money on Pain Relief, and how to find SingleCare Pain Relief coupons for the product you need.

Pain Relief FAQs

How much does Pain Relief cost without insurance?

Both over-the-counter and prescription Pain Relief medication and medical device prices will vary depending on type, brand, ingredients, dosage, and retailer. You can save as much as 80% on prescription Pain Relief medications and medical devices with a SingleCare Pain Relief coupon. Also, SingleCare discounts are available on over-the-counter products, like over-the-counter Pain Relief medications or devices, when prescribed by a physician. SingleCare is accepted at many nationwide pharmacies and retailers: CVS, Target, Long Drugs, Walmart, and many others.

How much does Pain Relief cost with insurance?

Insurance copays for prescription Pain Relief medications or medical devices will depend on your prescription and insurance plan. SingleCare can be a trustworthy way to save money even in comparison with insurance copays. To get the best price on Pain Relief, compare your insurance copay to SingleCare’s discount.

Does Medicare cover Pain Relief and how much does it cost?

Medicare insurance coverage on Pain Relief depends on the prescription and insurance plan. However, your copay cost will vary according to your plan, so it's a good idea to compare prices with your pharmacist. You will reliably save money with SingleCare savings card, and your savings may be better than your Medicare copays. SingleCare is accepted at large retailers, like Walmart, drugstores, like Walgreens, and supermarket pharmacies, like Harris Teeter.

What is the brand name of Pain Relief?

Many prescription and over-the-counter Pain Relief medications and basic medical devices have generic versions at a lower price. Search the SingleCare website or app for the Pain Relief you need to find generic alternatives and coupons that could cut your Pain Relief costs by up to 80%.

What is Pain Relief?

Pain Relief is the medical or home management of temporary (acute) or long-term (chronic) pain through medications, medical devices, therapy, or a combination of all three.

There are six main categories of Pain Relief medications available both with or without a prescription: NSAIDs, acetaminophen, counter-irritants, anesthetics, corticosteroids, and opioids. Other medications, such as antidepressants, anxiolytics (anti-anxiety medications), and anticonvulsants are sometimes prescribed for pain management. Many of these medications are classified as analgesics, that is, they relieve pain. Anesthetics, on the other hand, partially or totally remove the sensation of pain by numbing the nerves. Other medications have no analgesic or anesthetic properties.

Non-steroidal anti-inflammatory drugs (NSAIDs) are the most commonly used pain medication both with and without a prescription. These analgesic drugs, which include aspirin and ibuprofen, block the body's production of prostaglandins, substances that cause swelling, and fever.

Acetaminophen is another common over-the-counter and prescription-only analgesic that stands in a class on its own. Acetaminophen works similarly to NSAIDs but does not reduce swelling.

Counter-irritants are very common as over-the-counter pain relief medications. Neither analgesic, or anesthetic, these drugs work on the principle of the gate theory of pain: providing a surplus of non-pain signals “drowns out” pain signals. Counter-irritants are common in topical pain relief medications as well as cough and sore throat medicines and include capsaicin, menthol, eucalyptus, methyl salicylate, and camphor.

Anesthetics, such as lidocaine, numb the nerves and prevent nerve signals from getting produced or sent. They are used for the temporary relief of pain. Over-the-counter anesthetics are common in topical medications, such as Aspercreme (lidocaine) and Orajel (benzocaine), and are used to relieve pain and discomfort on the skin or in the mouth. Prescription anesthetics are commonly used in medical and dental procedures and some, like propofol, may also produce sleep (sedation).

Corticosteroids are the second-most prescribed Pain Relief medication for pain relief. Corticosteroids, such as cortisone, are anti-inflammatory drugs, not analgesics, but they provide fast-acting and long-lasting pain relief by dramatically reducing the swelling that causes pain. Some corticosteroids, such as hydrocortisone, are available over-the-counter in topical medications to treat skin discomfort and pain.

Opioids and opioid-like drugs are the most controlled analgesics but are commonly prescribed for both temporary and chronic pain. These drugs act by attaching to receptors in nerve cells and block certain nerve signals, including pain signals. These drugs, which include opium, morphine, codeine, and tramadol, are highly effective at reducing and even eliminating moderate to severe pain. Their effectiveness wears off within a couple of weeks as patients develop tolerance, so they are usually prescribed only for the short-term relief of pain.

Antidepressants provide moderate chronic pain relief by changing the chemistry of the central nervous system. The effects take one or two weeks to be evident. Anti-anxiety medications interfere with the chemicals that cause muscles to contract, so they help relieve muscle tension and muscle spasms that may be the cause of chronic pain. Finally, anticonvulsants slow down nerve signals and have been found to effectively treat nerve pain, such as that induced by carpal tunnel syndrome.

The most common and reliable medical devices for relieving pain involve applying heat, ice, or vibration. All of these medical devices work primarily on the gate theory of pain management – overwhelming the nervous system with other input to “drown out” the pain signals. Heat and ice also help to relieve swelling, and vibration devices help to loosen muscles and decrease muscle spasms.

A new generation of Pain Relief medical devices involve stimulating nerves, relaxing muscles, changing nerve chemistry, or overwhelming the nerves with other input using electromagnetism, electricity, lasers, and ultrasound. Many of these are wearable devices that can be used throughout the day in different contests.

Each specific formulation will have different remedial or curative effects. Search our website or app for the Pain Relief brand or name to find out more about that remedy: what it is, how it works, possible side effects, how much it costs, and how you can save money.

What are the side effects of Pain Relief?

Side effects will vary depending on the product and the underlying condition. Search our website or app for a specific Pain Relief brand or name to learn more about the possible side effects.

Where are Pain Relief coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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