What is Pain Relief: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Pain Relief overview

BRAND NAMES:

  • 7T Gummy ES, 8 Hour Pain Relief, 8HR Arthritis Pain Relief, 8HR Muscle Aches & Pain, Aphen, Arthritis Pain Relief, CareALL Non-Aspirin, Cetafen, Cetafen Extra, Children's Cough & Sore Throat, Children's Dye Free Pain and Fever, Children's Fever Reducer & Pain Reliever, Children's Mapap, Children's Non-Aspirin, Children's Pain & Fever, Alka-Seltzer, Alka-Seltzer Extra Strength, Alka-Seltzer Morning Relief, Back & Body, Bayer Back & Body, Bayer Women's, Bc Headache Powder, Bc Powder Arthritis Strength, Bufferin, Bufferin Extra Strength, Goody's Fast Pain Relief, Medi-Seltzer, Ohmni-Cen, Pain Relief, Quality Choice Effervescent Pain Relief, Quality Choice Effervescent Pain Relief, Medi-Seltzer, Pain Relief, Alka-Seltzer, Alka-Seltzer Extra Strength

Generic Names:

  • Pain Relief

Uses:

  • Treats headache, minor pain, body aches, and drowsiness or tiredness., Treats heartburn, acid indigestion, and sour stomach with headache, minor pain, or body aches. Also treats the symptoms of a hangover caused by drinking alcohol., Treats minor aches and pain and reduces fever.

Therapeutic Classes:

  • Analgesic, Antipyretic, Acetaminophen/Salicylate, Aspirin Combination, Acetaminophen Combination, Analgesic, Analgesic Combination, Salicylate, Antidote, Antipyretic, Antirheumatic, Platelet Aggregation Inhibitor, Salicylate, Aspirin Combination, Analgesic, Analgesic Combination, Antidote, Salicylate, Aspirin Combination

Forms:

  • Tablet, Fizzy Tablet, Liquid, Packet, Fizzy Tablet, Tablet, Long Acting Tablet, Fizzy Tablet, Tablet, Chewable Tablet, Dissolving Tablet, Powder, Liquid, Capsule, Liquid Filled Capsule

How it’s taken:

  • By mouth, By mouth, By mouth

What is Pain Relief used for?

What form(s) does Pain Relief come in

  • Tablet

  • Fizzy Tablet

  • Liquid

  • Packet

  • Fizzy Tablet

  • Tablet

  • Long Acting Tablet

  • Fizzy Tablet

  • Tablet

  • Chewable Tablet

  • Dissolving Tablet

  • Powder

  • Liquid

  • Capsule

  • Liquid Filled Capsule

What are common Pain Relief doses?

  • Bottle 237ML of 500MG/15ML

  • Tablet

Common Pain Relief prescriptions

  • Pain Relief
    125 boxs tablet

  • Pain Relief
    250 boxs tablet

How to take Pain Relief

  • The chewable tablet should be chewed or crushed before you swallow it.

  • Do not take this medicine for more than 10 days in a row, unless directed by your doctor.

  • If you are taking this medicine without the advice of your doctor, carefully read and follow the Drug Facts label and dosing instructions on the medicine package. Ask your doctor or pharmacist if you are not sure how to use this medicine.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Oral liquids: Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup. Do not use a spoon, syringe, or cup that came with a different medicine.

  • Oral liquid (with syringe): Shake the bottle well before each use.Remove the cap. Attach the syringe to the flow restrictor. Turn the bottle upside down.Pull back the syringe plunger until it is filled with the correct dose. Ask your doctor or pharmacist if you are not sure how much medicine to use.Slowly give the medicine into your child's mouth. Point the syringe so the medicine goes toward the inner cheek.

  • Oral liquid (with dropper): Shake the bottle well before each use.Remove the cap. Insert the dropper into the bottle. Withdraw the correct dose. Ask your doctor or pharmacist if you are not sure how much medicine to use.Slowly give the medicine into your child's mouth. Point the dropper so the medicine goes toward the inner cheek.

  • Extended-release tablet: Swallow the extended-release tablet whole. Do not crush, break, or chew it. Take this medicine with a full glass of water.

  • Use only the brand of medicine your doctor prescribed. Other brands may not work the same way.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • The chewable tablet should be chewed or crushed before you swallow it.

  • Oral liquid (with dropper): Shake the bottle well before each use.Remove the cap. Insert the dropper into the bottle. Withdraw the correct dose. Ask your doctor or pharmacist if you are not sure how much medicine to use.Slowly give the medicine into your child's mouth. Point the dropper so the medicine goes toward the inner cheek.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Oral liquid (with syringe): Shake the bottle well before each use.Remove the cap. Attach the syringe to the flow restrictor. Turn the bottle upside down.Pull back the syringe plunger until it is filled with the correct dose. Ask your doctor or pharmacist if you are not sure how much medicine to use.Slowly give the medicine into your child's mouth. Point the syringe so the medicine goes toward the inner cheek.

  • Use only the brand of medicine your doctor prescribed. Other brands may not work the same way.

  • Do not take this medicine for more than 10 days in a row, unless directed by your doctor.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Extended-release tablet: Swallow the extended-release tablet whole. Do not crush, break, or chew it. Take this medicine with a full glass of water.

  • If you are taking this medicine without the advice of your doctor, carefully read and follow the Drug Facts label and dosing instructions on the medicine package. Ask your doctor or pharmacist if you are not sure how to use this medicine.

  • Oral liquids: Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup. Do not use a spoon, syringe, or cup that came with a different medicine.

  • If you are using the effervescent tablet form of this medicine, dissolve the tablets fully in 4 ounces of water. Drink all of this mixture right away.

  • Oral routeIt is best to take this medicine with food or milk.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Follow the instructions on the medicine label if you are using this medicine without a prescription.

  • Follow the instructions on the medicine label if you are using this medicine without a prescription.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Oral routeIt is best to take this medicine with food or milk.

  • If you are using the effervescent tablet form of this medicine, dissolve the tablets fully in 4 ounces of water. Drink all of this mixture right away.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Follow the instructions on the medicine label if you are using this medicine without a prescription.

  • Drink a full glass of water with each dose of this medicine.

  • If you are using the effervescent tablet form of this medicine, dissolve the tablets fully in 4 ounces of water. Drink all of this mixture right away.

  • Oral routeIt is best to take this medicine with food or milk.

  • If you are using the effervescent tablet form of this medicine, dissolve the tablets fully in 4 ounces of water. Drink all of this mixture right away.

  • Follow the instructions on the medicine label if you are using this medicine without a prescription.

  • Oral routeIt is best to take this medicine with food or milk.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Drink a full glass of water with each dose of this medicine.

What to do if you miss a dose of Pain Relief

  • Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • If this medicine has a strong vinegar smell, throw it away and do not use it.

  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.

  • Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Pain Relief contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to acetaminophen.

  • You should not use this medicine if you have had an allergic reaction to aspirin, citric acid, or sodium bicarbonate. You should not use this medicine during the last 3 months of pregnancy. This medicine should not be given to children or teenagers with fever, chickenpox, or symptoms of the flu or viral infection. Aspirin can cause a serious disease called Reye's syndrome in children or teenagers. You should not use this medicine if you have an active stomach ulcer or any kind of bleeding problem.

  • You should not use this medicine if you have had an allergic reaction to aspirin, caffeine, or any other ingredients listed on the package label. You should not use this medicine during the last 3 months of pregnancy. Do not give this medicine to children younger than 12 years old, unless a doctor tells you to. This medicine should not be given to children or teenagers with fever, chickenpox, or symptoms of the flu or viral infection. Aspirin can cause a serious disease called Reye's syndrome in children or teenagers. You should not use this medicine if you are on a low-salt diet, unless your doctor tells you to. You should not use this medicine if you have an active stomach ulcer or any kind of bleeding problem.

Pain Relief warnings

  • Make sure your doctor knows if you are pregnant or breast feeding. Tell your doctor if you have arthritis, asthma, diabetes, gout, or a bleeding disorder such as hemophilia. Make sure your doctor knows if you have a stomach disorder such as an ulcer, heartburn that last or come back frequently, or GERD (reflux disease).

  • Tell your doctor if your symptoms get worse or last longer than 10 days.

  • Bloody vomit or vomit that looks like coffee grounds.

  • Fever, chills, lightheadedness, fainting.

  • Dark urine, yellowing of your skin or the whites of your eyes.

  • Pain that lasts longer than 10 days.

  • Pale skin, unusual bleeding, bruising, or weakness.

  • Redness or swelling.

  • Severe stomach pain.

  • Ringing in your ears that will not stop.

  • Worsening pain or new symptoms.

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have asthma, gout, arthritis, or diabetes. Tell your doctor if you have liver disease, bleeding problems such as hemophilia, frequent upset stomach, or a stomach disorder such as an ulcer, heartburn, or GERD (reflux disease).

  • Some forms of this medicine may contain sodium and phenylalanine. Read the label before using this medicine. Tell your doctor if you are on a salt-restricted diet, or if you have phenylketonuria (PKU).

  • Tell your doctor if you have had a fever for more than 3 days, a sore throat for more than 2 days, or pain for more than 10 days. If you are using this medicine to treat a hangover, do not use for longer than 2 days.

  • Make sure any doctor or dentist who treats you knows if you have taken this medicine recently. This medicine may cause problems during surgery or procedures.

  • Unusual bleeding, bruising, or weakness.

  • Redness or swelling.

  • Severe stomach pain.

  • Ringing in your ears that will not stop, problems with hearing.

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney or liver disease. Tell your doctor if you have phenylketonuria (PKU). Some brands of acetaminophen contain aspartame, which can make PKU worse.

  • This medicine contains acetaminophen. Read the labels of all other medicines you are using to see if they also contain acetaminophen, or ask your doctor or pharmacist. Do not use more than 4 grams (4,000 milligrams) total of acetaminophen in one day. For Tylenol® Extra Strength, it is not safe to take more than 3 grams (3,000 milligrams) in 1 day.

  • Call your doctor if your symptoms do not improve or if they get worse.

  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Unusual bleeding or bruising

  • Vomiting blood or material that looks like coffee grounds

Pain Relief interactions

  • Some medicines and foods can affect how acetaminophen works. Tell your doctor if you are taking a blood thinner, such as warfarin.

  • Do not drink alcohol while you are using this medicine. Acetaminophen can damage your liver, and alcohol can increase this risk. Do not take acetaminophen without asking your doctor if you have 3 or more drinks of alcohol every day.

  • Call your doctor if your symptoms do not improve or if they get worse.

  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Aspirin can cause stomach bleeding. Drinking alcohol can make this worse. If you have 3 or more drinks of alcohol every day, ask your doctor if you should use this medicine. One drink of alcohol is the same as 4 ounces of wine, 12 ounces of beer, or 1 ounce of hard liquor (gin, whiskey, and others).

  • Make sure your doctor knows if you are taking any medicine to treat diabetes or gout. Tell your doctor if you take a blood thinner such as warfarin (Coumadin®), or if you have recently received medicine to treat a blood clot such as urokinase (Abbokinase®), streptokinase (Streptase®), or alteplase (Activase®).

  • Avoid using other pain or arthritis medicine such as ibuprofen (Advil®, Motrin®), naproxen (Aleve®), ketoprofen (Oruvail®), indomethacin (Indocin®), Celebrex®, Daypro®, or Relafen® while you are using this medicine.

  • Avoid foods, drinks, or other medicines that contain caffeine or stimulants, including diet pills. If you take them together with this medicine, you may get too much caffeine and have unwanted side effects.

  • Make sure that none of the other medicines you are using also contain aspirin.

  • There are many other medicines that should not be taken together with an antacid, such as sodium bicarbonate. Tell your doctor about all other medicines you are using.

  • Make sure your doctor knows if you are also using a blood thinner such as warfarin (Coumadin®).

  • Aspirin can cause stomach bleeding. Drinking alcohol can make this worse. If you have 3 or more drinks of alcohol every day, ask your doctor if you should use this medicine. One drink of alcohol is the same as 4 ounces of wine, 12 ounces of beer, or 1 ounce of hard liquor (gin, whiskey, and others).

  • Make sure that none of the other medicines you are using also contain aspirin.

Pain Relief side effects

Serious Side Effects

  • Dark urine or pale stools, nausea, vomiting, loss of appetite, severe stomach pain, yellow skin or eyes

  • Unusual bleeding or bruising

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Fever or a sore throat that lasts longer than 3 days, or pain that lasts longer than 5 days

  • Vomiting blood or material that looks like coffee grounds

  • Bloody or black, tarry stools

  • Lightheadedness, fainting, sweating, or weakness

  • Severe stomach pain.

  • Unusual bleeding, bruising, or weakness.

  • Ringing in your ears that will not stop, problems with hearing.

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Bloody or black, tarry stools.

  • Bloody vomit or vomit that looks like coffee grounds.

  • Pain that lasts longer than 10 days, worsening pain, lasting tiredness or drowsiness, or new symptoms.

  • Redness or swelling.

  • Dark urine, yellowing of your skin or the whites of your eyes.

  • Redness or swelling.

  • Worsening pain or new symptoms.

  • Fever, chills, lightheadedness, fainting.

  • Pale skin, unusual bleeding, bruising, or weakness.

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Bloody or black, tarry stools.

  • Bloody vomit or vomit that looks like coffee grounds.

  • Ringing in your ears that will not stop.

  • Pain that lasts longer than 10 days.

  • Severe stomach pain.

Less Serious Side Effects

  • Trouble sleeping.

  • Slight ringing in your ears, problems with hearing.

  • Mild stomach pain, nausea, heartburn.

  • Feeling restless, jittery, or irritated.

  • Mild stomach pain, nausea, or heartburn.

  • Slight ringing in your ears.

  • Trouble sleeping.