What is Phendimetrazine ER: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Phendimetrazine ER overview

BRAND NAMES:

  • Bontril Slow-Release, Bontril Slow-Release, Phendiet, Phendiet-105

Generic Names:

  • Phendimetrazine Tartrate Er

Uses:

  • Used with a diet plan for weight loss. This medicine is an appetite suppressant.

Therapeutic Classes:

  • Appetite Suppressant, Centrally Acting

Forms:

  • Capsule, Long Acting Capsule, Tablet

How it’s taken:

  • By mouth

What is Phendimetrazine ER used for?

What form(s) does Phendimetrazine ER come in

  • Capsule

  • Long Acting Capsule

  • Tablet

What are common Phendimetrazine ER doses?

  • Capsule Extended Release 24 Hour 105MG

Common Phendimetrazine ER prescriptions

  • Phendimetrazine Tartrate ER
    105mg capsule extended release 24 hour

How to take Phendimetrazine ER

  • Your doctor will tell you how much medicine to use. Do not use more than directed. Carefully follow your doctor's instructions for a reduced-calorie diet plan and regular exercise.

  • Take the tablet 1 hour before a meal. Take the capsule 30 to 60 minutes before a meal.

  • Swallow the capsule whole. Do not break, crush, or chew it.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Your doctor will tell you how much medicine to use. Do not use more than directed. Carefully follow your doctor's instructions for a reduced-calorie diet plan and regular exercise.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Swallow the capsule whole. Do not break, crush, or chew it.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Take the tablet 1 hour before a meal. Take the capsule 30 to 60 minutes before a meal.

What to do if you miss a dose of Phendimetrazine ER

Phendimetrazine ER contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to phendimetrazine, or if you also use any other stimulant or diet pill. Do not use this medicine if you are feeling agitated or if you have glaucoma, an overactive thyroid, or a history of heart and blood vessel disease (such as uncontrolled high blood pressure, arrhythmia, clogged arteries, heart failure, pulmonary hypertension, or stroke). Do not use this medicine if you are pregnant or breastfeeding.

Phendimetrazine ER warnings

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.

  • Tell your doctor if you have kidney disease, diabetes, heart valve disease, or high blood pressure.

  • This medicine may cause a rare but serious condition called pulmonary hypertension.

  • Never use more than your prescribed dose. This medicine can be habit-forming. It is not meant for long-term use.

  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.

  • This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

Phendimetrazine ER interactions

  • Do not use this medicine if you have used an MAO inhibitor within the past 14 days.

  • Some medicines and foods can affect how phendimetrazine works. Tell your doctor if you are also using guanethidine, sibutramine, or insulin or diabetes medicine.

  • This medicine may cause a rare but serious condition called pulmonary hypertension.

  • Never use more than your prescribed dose. This medicine can be habit-forming. It is not meant for long-term use.

  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.

  • This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Phendimetrazine ER side effects

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Change in how much or how often you urinate

  • Chest pain, shortness of breath, or trouble breathing

  • Confusion, feelings of panic, or seeing, hearing, or feeling things that are not there

  • Fainting, swelling of your feet or lower legs

  • Fast, pounding, or uneven heartbeat

Less Serious Side Effects

  • Sweating or flushing

  • Feeling restless, excited, or agitated

  • Dry mouth, constipation, diarrhea, nausea, or stomach pain

  • Increased or decreased interest in sex

  • Tremors or shaking

  • Headache, blurred vision

Subscribe to our savings newsletter

Health education, drug info, wellness & more

By clicking 'Subscribe', I agree to SingleCare's Terms & Conditions.