What is Phospha 250 Neutral: Uses, Warnings & Interactions

Follow the prescriber’s instructions and dosage. Do not use more than directed.

Take Phospha 250 Neutral tablets four times daily.

Take the first three doses with a meal. Take the last dose at bedtime.

Swallow the tablet whole with a glass of water.

Store the tablets in a light-resistant container at room temperature.

Ask the prescriber or pharmacist what to do if a dose is missed.

This medicine is not right for everyone. 

Do not use it if you have had an allergic reaction to any ingredients in the tablet or have:

• Infected phosphate stones

• Severe kidney impairment

• High phosphate levels (hyperphosphatemia)

The prescriber will need regular visits and blood or urine tests to monitor treatment. Keep all appointments.

Tell the prescriber if you are pregnant, breastfeeding, or have:

• Heart disease

• Kidney problems

• Severe liver problems

• Dehydration

• Fluid retention (peripheral or pulmonary edema)

• High sodium levels

• High blood pressure

• Preeclampsia

• Swollen pancreas

• Adrenal gland problems including Addison’s disease

• Underactive parathyroid gland

• Rickets

• Myotonia congenita, a hereditary condition characterized by stiff muscles

Immediately tell the prescriber if you get severely injured or burned or tell the healthcare team treating you you’re taking this supplement. Phospha 250 Neutral may cause problems in people with extensive tissue breakdown.

People with kidney stones might pass those stones when first taking Phospha 250 Neutral.

When first started, Phospha 250 Neutral tablets may have a mild laxative effect for the first few days. 

High-dose sodium phosphate and potassium phosphate supplements can have serious side effects including:

• High phosphate levels

• High sodium levels

• High potassium levels

• Weak bones (osteomalacia)

Know the symptoms of possible electrolyte imbalances and contact a healthcare professional if they are experienced.

Tell the prescriber about all the medications and supplements you take, particularly:

• Blood pressure drugs (particularly ACE inhibitors, angiotensin II receptor blockers, guanethidine, hydralazine, diazoxide, and methyldopa)

• Corticosteroids, particularly fludrocortisone or corticotropin

• Rauwolfia alkaloid drugs or supplements such as reserpine, yohimbine (yohimbe), or serpentina (Indian snakeroot).

• Potassium-sparing diuretics such as spironolactone or triamterene

• Potassium supplements or salt substitutes

• Calcium-containing supplements or medications

• Vitamin D supplements or medications

• Cyclosporine, digoxin, tacrolimus

Tell the prescriber if you are on a salt-restricted or low-potassium diet.

Do not take an antacid that contains aluminum, calcium, or magnesium while taking Phospha 250 Neutral. Antacids may decrease the absorption or effectiveness of phosphate supplements.