What is Qulipta? Uses, warnings & side effects

Medically reviewed by Josephine Bawab, Pharm.D.
Licensed Pharmacist
Updated Oct 14, 2025  •  Published Nov 10, 2021
Datos Verificados

Qulipta is a brand-name migraine preventive treatment. The active ingredient in Qulipta tablets is atogepant. It blocks a chemical that causes blood vessels to widen quickly at the start of a migraine, which is the cause of many of the worst migraine symptoms, including pain. Atogepant can’t stop migraines. Instead, people take one tablet daily to reduce the incidence of migraine attacks.

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Qulipta overview

BRAND NAMES:

  • Qulipta

Generic Names:

  • Atogepant

Uses:

  • Prevents migraine headaches

Therapeutic Classes:

  • Anti-migraine, calcitonin gene-related peptide receptor (CGRP) antagonist

Forms:

  • Tablet

How it’s taken:

  • By mouth

What is Qulipta used for?

Daily doses of Qulipta help reduce the incidence of migraine headaches in adults. 

Key takeaways

  • Take Qulipta as prescribed by your healthcare provider. It can be taken with or without food.

  • Let your prescribing healthcare provider know your complete medical history, including all medical conditions you have and any other prescription and over-the-counter medications you take.

  • Get medical help right away if you experience a serious allergic reaction caused by Qulipta.

  • Speak to your healthcare provider if you experience an increase in blood pressure or Raynaud’s phenomenon, which is a circulation problem that can lead to your fingers or toes feeling numb, cool, or painful, or changing color from pale, to blue, to red.

What form(s) does Qulipta come in?

  • Tablet

    • 10 mg

    • 30 mg

    • 60 mg

What are common Qulipta dosages?

  • To prevent episodic migraine headaches: One tablet (10 mg, 30 mg, or 60 mg) taken by mouth once daily with or without food

  • To prevent chronic migraine headaches: One 60 mg tablet taken by mouth once daily with or without food

Qulipta images - What does Qulipta look like?

  • Qulipta
    10mg tablet

  • Qulipta
    30mg tablet

  • Qulipta
    60mg tablet

How to take Qulipta

  • Follow all the prescriber’s instructions.

  • Do not take more tablets than prescribed or take them more often than prescribed.

  • Please read the Patient Medication Information sheet included with the medicine.

  • Take only one dose daily. 

  • Take Qulipta with or without food.

  • Swallow the tablet whole with a drink of water.

  • If you can’t swallow a tablet, ask the prescriber for advice.

  • Store Qulipta tablets at room temperature.

What to do if you miss a dose of Qulipta

  • A missed dose should be taken right away.

  • If it’s almost time for the next dose, take that dose as scheduled and skip the missed dose.

  • Do not take two doses to make up for a missed dose.

Qulipta contraindications - Who shouldn't take Qulipta?

  • Not everyone can safely take Qulipta.

  • People with known allergies to atogepant should not take Qulipta tablets.

Qulipta warnings

  • Tell any doctor or other healthcare provider who treats you that you are taking Qulipta. 

  • Keep all healthcare appointments so that the prescriber can monitor your progress.

  • Tell the prescriber if you are pregnant, breastfeeding, have circulation problems in your fingers and toes, or have kidney or liver problems.

  • People with liver or kidney problems may need to take a reduced Qulipta dose or avoid Qulipta altogether.

  • The most serious adverse effects of Qulipta are severe allergic reactions. If this happens, Qulipta treatment should be stopped.

Qulipta interactions & what to avoid when taking Qulipta

  • A wide spectrum of drugs can interfere with Qulipta. The list is very long and includes many commonly used antibiotics, antifungals, blood pressure medications, anticonvulsants, corticosteroids, cancer treatments, supplements, and even grapefruit juice. 

  • To avoid possible drug interactions, keep a list of all the prescription drugs, over-the-counter medications, vitamins, supplements, and herbal remedies you take and share it with the prescribing healthcare professional before taking Qulipta. Doses may need to be modified, and some drugs may need to be discontinued.

  • Do not start new medications without consulting the prescriber. Your Qulipta dose may need to be modified.

  • People taking Qulipta can take other migraine drugs.

Qulipta side effects - How does Qulipta make you feel?

Talk to a healthcare provider if you notice any serious side effects of Qulipta, including an allergic reaction, high blood pressure, or Raynaud’s phenomenon.

Serious side effects:

  • Allergic reactions, including anaphylaxis:

    • Itchy skin

    • Hives

    • Skin rash

    • Swelling of the face, mouth, or tongue

    • Difficulty breathing, fast breathing, or wheezing

    • Difficulty swallowing

    • Throat tightness

    • Confusion

    • Fatigue

    • Dizziness

    • Fainting

  • Increase in blood pressure

  • Raynaud’s phenomenon:

    • Fingers or toes feeling numb, cool, or painful

    • Change in color of fingers or toes from pale to blue to red

Less serious side effects:

  • Nausea

  • Constipation

  • Tiredness or sleepiness

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Medically reviewed by Josephine Bawab, Pharm.D.
Licensed Pharmacist

Josephine Bawab, Pharm.D., graduated from Virginia Commonwealth University School of Pharmacy. She began working in community pharmacy in 2012 and has worked for multiple chain pharmacies since then. She is passionate about helping patients and precepting students. She currently works and resides in Virginia, where she is just a few minutes away from the beach.

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