What is Repatha SureClick: Uses, Warnings & Interactions

Your doctor will prescribe your exact dose and tell you how often it should be given.

Please read the Patient Information sheet before starting this medication.

The SureClick autoinjector injects one dose of Repatha under the skin.

• Do not use the SureClick injection pen more than once.

Always check the SureClick injector before using it. Do not use it if the medicine is cloudy, the device is damaged, parts are missing, or the expiration date has passed.

• Do not use the SureClick injector pen if you drop it.

• Do not shake the injector pen.

A healthcare provider will demonstrate how to give injections. Make sure you understand all instructions before giving yourself an injection. 

You will be shown the body areas where this shot can be given: 

• Self-administered injections can be given on the thigh or abdomen.

• A caregiver can administer an injection in the outer area of the upper arm. 

• Use a different body area for each injection. 

• Do not inject into skin with cuts, scrapes, scars, or stretch marks.

Always clean the injection area with an alcohol wipe before injecting the medicine.

To give an injection: 

• Review the Instructions for Use that are included in the carton.

• Remove the SureClick autoinjector from the refrigerator.

• Allow the autoinjector to get to room temperature, letting it warm for at least 30 minutes.

• Pull the orange cap off the injector when ready to inject.

• Stretch or pull the skin to provide an injection surface.

• Place the yellow safety guard at the end of the injector against the skin surface at a 90-degree angle.

• Without pressing the gray button, push the injector down until it can’t move anymore.

• Press the gray button. It will make a clicking sound.

• The injection takes 15 seconds. Keep the injector pushed firmly against the skin during the injection. 

• When the window turns yellow, the injection is finished.

• Remove the injector and dispose of it in a sharps container.

For 420 mg injections, use three SureClick pens to give three injections one after another.

• All three injections must be completed in 30 minutes.

Store this medicine in its original carton in the refrigerator. Do not freeze.

The medicine can be stored at room temperature for up to 30 days. Dispose of any unused SureClick pens after that.

Never allow the Repatha SureClick pen to sit in direct sunlight.

A missed biweekly dose can be taken seven days after its scheduled time. 

If more than seven days have passed, skip the missed dose.

Take the next dose on its scheduled day.

A missed monthly dose can be taken seven days after its scheduled time. Take the next dose on its scheduled day.

If more than seven days have passed, take the missed dose, but reschedule the next dose for 30 days after the missed dose was injected.

This medicine is not right for everyone. 

Do not use it if you had an allergic reaction to evolocumab.

Make sure other doctors or other healthcare professionals treating you know about your Repatha injections. 

The prescriber will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Before starting Repatha, tell the prescriber about all your medical conditions, particularly latex allergies.

Tell the prescriber if you are pregnant or breastfeeding.

Repatha can cause serious allergic reactions. If you experience an allergic reaction, stop using Repatha and talk to the prescriber.

Tell the prescriber about all the medications and supplements you take or plan to take.

Tell other healthcare providers about Repatha before they prescribe a new medication.