What is Robinul? Uses, warnings & side effects

Updated May 14, 2025  •  Published Jul 5, 2023

Robinul overview

BRAND NAMES:

  • Glycopyrrolate Novaplus, Robinul, Cuvposa, Glycate, Robinul Forte

Generic Names:

  • Glycopyrrolate

Uses:

  • Treats peptic ulcers when you cannot take medicine by mouth or when treatment needs to be fast. Also used before and during surgery to dry up your mouth, throat, and stomach and to prevent heart rhythm problems., Treats peptic ulcers. Also used to treat severe drooling caused by certain conditions (such as cerebral palsy) in children 3 to 16 years of age.

Therapeutic Classes:

  • Cholinergic Antagonist, Gastrointestinal Agent

Forms:

  • Injectable, Liquid, Tablet

How it’s taken:

  • By injection, By mouth

What is Robinul used for?

What form(s) does Robinul come in?

  • Injectable

  • Liquid

  • Tablet

What are common Robinul dosages?

  • Tablet 1mg

Robinul images - What does Robinul look like?

  • Robinul
    1mg tablet

  • Robinul
    5ml of 1mg/5ml vial

How to take Robinul

  • Your doctor will prescribe your exact dose and tell you how often it should be given. It is given as a shot into a muscle or as a needle placed into a vein.

  • This medicine may be given 30 to 60 minutes before receiving anesthesia, a narcotic pain reliever, or sleep medicine, or during surgery.

  • Injection routeA nurse or other health provider will give you this medicine.

  • Injection routeYou will be shown the body areas where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas.

  • Injection routeUse a new needle and syringe each time you inject your medicine.

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.

  • You or your child should take the oral liquid at least one hour before or two hours after meals.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

What to do if you miss a dose of Robinul

  • Injection routeCall your doctor or pharmacist for instructions.

  • Injection routeAsk your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine, containers, and other supplies. Throw away old medicine after the expiration date has passed.

  • Injection routeThrow away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Oral routeAsk your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.

Robinul contraindications - Who shouldn't take Robinul?

  • This medicine is not right for everyone. Do not receive it if you had an allergic reaction to glycopyrrolate, or if you have glaucoma, myasthenia gravis, or trouble urinating because of an enlarged prostate or other blockage, unstable heart or blood vessel problems, or stomach or bowel problems (including, blockage, severe ulcerative colitis, toxic megacolon).

  • You should not use this medicine if you have had an allergic reaction to glycopyrrolate, or if you have glaucoma, myasthenia gravis, or trouble urinating because of an enlarged prostate or other blockage. You should not use this medicine if you have certain problems with digestion, including severe colitis or something physically blocking digestion. Do not take this medicine if you or your child is receiving potassium chloride tablets or other potassium supplements (in capsule or tablet forms).

Robinul warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart disease, heart failure, heart rhythm problems, thyroid problems, high blood pressure, nerve problems, hiatal hernia, heartburn, colitis (swelling of the bowels), or digestion problems. Tell your doctor if you have had a surgery in your bowels (including colostomy or ileostomy).

  • If this medicine is being used by your child, make sure the doctor knows if your child has Down's syndrome, muscle spasms, or brain damage.

  • This medicine may cause the following problems:Eye or vision problems (including glaucoma)Bowel blockageHeart rhythm problems

  • This medicine may make you dizzy, drowsy, or cause blurred vision. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

  • This medicine may keep you from sweating enough, which may cause your body to get too hot. Be careful in hot weather, or while doing activities, including exercising or using a sauna or whirlpool.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Muscle weakness or stiffness.

  • Seizures.

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you or your child has kidney disease, liver disease, heart disease, congestive heart failure, heart rhythm problems, high blood pressure, nerve problems, an enlarged prostate, or an overactive thyroid. Tell your doctor if you or your child has hiatal hernia, heartburn, diarrhea, colitis, a colostomy or ileostomy, or any other problems with your stomach, bowel, or digestive system.

  • This medicine may cause constipation or diarrhea. Constipation or diarrhea can be an early symptom of a serious bowel problem. Stop using this medicine and check with your doctor right away if you or your child has constipation, diarrhea, abdominal or stomach distention (swelling), pain, nausea, or vomiting.

  • Stop using this medicine and check with your doctor right away if your child is unable to urinate, has dry diapers or undergarments, or has the following symptoms while using this medicine: crying, irritability, decrease in the frequency of urine, or difficult or painful urination.

  • If you or your child develops a skin rash, hives, or any allergic reaction to this medicine, stop taking the medicine and check with your doctor as soon as possible.

  • Be careful during hot weather or exercising. This medicine may make you or your child sweat less, so you could get overheated more easily.

  • This medicine may make you drowsy or cause blurred vision. Avoid driving, using machines, or doing anything else that could be dangerous if you or your child is not alert.

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

  • Trouble with breathing.

  • Warmth or redness in your face, neck, arms, or upper chest.

Robinul interactions & what to avoid when taking Robinul

  • Some medicines can affect how glycopyrrolate works. Tell your doctor if you are using any of the following:Atropine, dicyclomine, potassium chloride, scopolamineMedicine to treat depression (including TCAs)Medicine to treat Parkinson's diseasePhenothiazine medicine

  • If this medicine is being used by your child, make sure the doctor knows if your child has Down's syndrome, problems with muscle spasms, or brain damage.

  • This medicine may keep you from sweating enough, which may cause your body to get too hot. Be careful in hot weather, or while doing activities such as exercising or using a sauna or whirlpool.

  • This medicine may make you dizzy, drowsy, or cause blurred vision. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.

  • This medicine may cause constipation or diarrhea. Constipation or diarrhea can be an early symptom of a serious bowel problem. Stop using this medicine and check with your doctor right away if you or your child has constipation, diarrhea, abdominal or stomach distention (swelling), pain, nausea, or vomiting.

  • Stop using this medicine and check with your doctor right away if your child is unable to urinate, has dry diapers or undergarments, or has the following symptoms while using this medicine: crying, irritability, decrease in the frequency of urine, or difficult or painful urination.

  • If you or your child develops a skin rash, hives, or any allergic reaction to this medicine, stop taking the medicine and check with your doctor as soon as possible.

  • Make sure your doctor knows if you or your child is receiving amantadine (Symmetrel®), atenolol (Tenormin®), digoxin (Lanoxin®), haloperidol (Haldol®), metformin (Glucophage®), or levodopa (Sinemet®).

  • Be careful during hot weather or exercising. This medicine may make you or your child sweat less, so you could get overheated more easily.

  • This medicine may make you drowsy or cause blurred vision. Avoid driving, using machines, or doing anything else that could be dangerous if you or your child is not alert.

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

Robinul side effects - How does Robinul make you feel?

Serious Side Effects

  • Seizures

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Blurred vision or other changes in vision, sensitivity of the eyes to light

  • Decrease in how much or how often you urinate

  • Diarrhea, severe constipation or stomach pain

  • Fast, slow, or uneven heartbeat

  • Fever, sweating

  • Muscle weakness or stiffness

  • Warmth or redness in your face, neck, arms, or upper chest.

  • Lightheadedness or fainting.

  • Muscle weakness or stiffness.

  • Abdominal pain or swelling.

  • Decrease in how much or how often you urinate, painful urination.

  • Diarrhea or constipation.

  • Fast or pounding heartbeat.

  • Fever, chills, cough, sore throat, stuffy or runny nose, and body aches.

  • Trouble with breathing.

Less Serious Side Effects

  • Unable to have or keep an erection in male patients

  • Headache

  • Dry mouth, loss of taste

  • Redness, pain, swelling, or itching where the injection is given

  • Confusion, nervousness, trouble sleeping

  • Nausea, vomiting

  • Vision problems, sensitivity to light.

  • Dry mouth.

  • Nasal congestion.

  • Flushing.

  • Light bothering your eyes.

  • Confusion, nervousness.

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