Salagen is an FDA-approved, brand-name, prescription drug used to treat dry mouth symptoms caused by head and neck radiation therapy or Sjögren's syndrome. The active ingredient in Salagen, pilocarpine hydrochloride, stimulates nerves in the salivary glands to produce more saliva. The retail price of Salagen is $215.30, but with SingleCare's Salagen coupon, it costs $29.52.
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Prices updated: 05/16/2026
Salagen is an FDA-approved, brand-name, prescription drug used to treat dry mouth symptoms caused by head and neck radiation therapy or Sjögren's syndrome. The active ingredient in Salagen, pilocarpine hydrochloride, stimulates nerves in the salivary glands to produce more saliva. The retail price of Salagen is $215.30, but with SingleCare's Salagen coupon, it costs $29.52.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Pilocarpine Hcl Retail Price | Pilocarpine Hcl SingleCare Price |
|---|---|---|
| CVS Pharmacy | $129.60 | $40.50 |
| Walmart | $79.20 | $47.70 |
| Walgreens | $52.20 | $43.20 |
| Kroger Pharmacy | $148.50 | $52.20 |
| Albertsons Pharmacy | $162.90 | $31.50 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Salagen is an FDA-approved, brand-name, prescription drug used to treat dry mouth symptoms caused by head and neck radiation therapy or Sjögren's syndrome. The active ingredient in Salagen, pilocarpine hydrochloride, stimulates nerves in the salivary glands to produce more saliva. The retail price of Salagen is $215.30, but with SingleCare's Salagen coupon, it costs $29.52.
Patients can expect to pay a cash price of $215.30 for Salagen. $29.52 per 90, 5mg tablets is all you pay for the same prescription with a SingleCare Salagen prescription discount card. For most of your prescription drug needs, you can save as much as 80% with a SingleCare prescription savings card.
The amount of your Salagen copay depends on the quantity and dosage prescribed as well as the policy of your insurance plan. With SingleCare, Salagen costs as little as $29.52 for 90, 5mg tablets, which may be lower than your insurance copay. Ask your pharmacist to do a price comparison.
Salagen is usually not covered by Medicare Part D and Medicare Advantage prescription drug plans, but the generic, pilocarpine, is. For patients paying cash, however, a SingleCare Salagen coupon could lower your cost to $29.52.
Salagen is a brand-name prescription drug. Generic versions of Salagen are available from Impax, Aurobindo, Lannett, and other generic manufacturers. All generic versions of Salagen are FDA-approved to treat dry mouth symptoms due to radiation therapy or Sjögren's syndrome. You can find SingleCare Salagen coupons on the SingleCare website or app to use on generic or brand-name Salagen.
Salagen is a brand-name prescription drug used to relieve the dry mouth symptoms caused by head and neck radiation therapy or Sjögren's syndrome, a condition in which the immune system “misfires” and mistakenly attacks cells in the saliva and tear glands. The active ingredient in Salagen, pilocarpine, acts like a neurotransmitter called acetylcholine to activate acetylcholine receptors in the central nervous system and salivary glands. Stimulation of acetylcholine receptors in the salivary glands helps promote the secretion of saliva.
Salagen is available as a 5 mg or 7.5 mg oral tablet. It is usually started as a 5 mg tablet taken three times daily for head and neck cancer patients. The usual dose for head and neck cancer patients is around 15 to 30 mg per day. It may take up to three months for Salagen to provide maximum benefits. For people with Sjögren's syndrome, Salagen may take up to six weeks to start providing maximum benefits. For Sjögren's syndrome, it is usually taken as a 5 mg tablet four times daily.
People with liver problems should be started on a lower dose of Salagen than normal. Those with liver impairment may start treatment with Salagen by taking 5 mg twice daily.
The most common side effects of Salagen are sweating, nausea, runny nose (rhinitis), diarrhea, flushing of the skin, and chills. Salagen may also cause dizziness, weakness (asthenia), and increased urination. Consult a healthcare provider if you experience any side effects with Salagen, or if side effects persist or worsen.
Rare side effects of Salagen reported in head and neck cancer patients include anxiety, increased appetite, slow heart rate, confusion, abnormal dreams, and depression. Serious side effects of Salagen include blurred vision and pulmonary edema (fluid in the lungs. Patients with asthma or COPD should use caution while on treatment with Salagen.
Toxicity or overdose are rare when Salagen is used as prescribed. However, symptoms of pilocarpine toxicity include diarrhea, low blood pressure, confusion, tremors, diarrhea, and changes in heart rate.
Allergic reactions are rare but include hives, rash, itching, and difficulty breathing. Consult a physician immediately if you experience a Salagen allergic reaction.
Talk to your doctor or healthcare professional for additional information and medical advice regarding other possible side effects or drug interactions.
Gerardo Sison, Pharm.D., graduated from the University of Florida. He has worked in both community and hospital settings, providing drug information and medication therapy management services. As a medical writer, he hopes to educate and empower patients to better manage their health and navigate their treatment plans.
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SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
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