Seysara is a tetracycline-class drug that is used to treat moderate to severe acne vulgaris. Seysara is a once-daily oral tablet that can be used in adults, or children who are at least nine years old. Seysara is only available as a brand-name prescription drug. Currently, there is no generic version of Seysara on the U.S. market. The average retail price for 30, 100mg tablets of Seysara is $1,426.54 before discounts and insurance. You can save on the cost of this medication when you use SingleCare's free Seysara coupons. With our Seysara coupons or prescription savings card, 30, 100mg tablets of Seysara costs just $1,063.81. You can use our coupons or discount cards at participating pharmacies across the U.S.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 12/20/2025
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Seysara is a tetracycline-class drug that is used to treat moderate to severe acne vulgaris. Seysara is a once-daily oral tablet that can be used in adults, or children who are at least nine years old. Seysara is only available as a brand-name prescription drug. Currently, there is no generic version of Seysara on the U.S. market. The average retail price for 30, 100mg tablets of Seysara is $1,426.54 before discounts and insurance. You can save on the cost of this medication when you use SingleCare's free Seysara coupons. With our Seysara coupons or prescription savings card, 30, 100mg tablets of Seysara costs just $1,063.81. You can use our coupons or discount cards at participating pharmacies across the U.S.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Seysara Retail Price | Seysara SingleCare Price |
|---|---|---|
| CVS Pharmacy | $1281.00 | $1124.10 |
| Walmart | $1332.00 | $1145.40 |
| Kroger Pharmacy | $1302.90 | $1141.50 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Seysara is a tetracycline-class drug that is used to treat moderate to severe acne vulgaris. Seysara is a once-daily oral tablet that can be used in adults, or children who are at least nine years old. Seysara is only available as a brand-name prescription drug. Currently, there is no generic version of Seysara on the U.S. market. The average retail price for 30, 100mg tablets of Seysara is $1,426.54 before discounts and insurance. You can save on the cost of this medication when you use SingleCare's free Seysara coupons. With our Seysara coupons or prescription savings card, 30, 100mg tablets of Seysara costs just $1,063.81. You can use our coupons or discount cards at participating pharmacies across the U.S.
The average cost of Seysara without insurance is about $1,426.54. With a SingleCare prescription discount card you could see significant savings on your Seysara prescription costs. When you use a SingleCare discount card you pay as little as $1,063.81 for Seysara.
The cost of Seysara with insurance can vary by insurance plan and provider. Your pharmacist or an insurance agent from your plan can help you calculate your copay for this medication with your insurance. However, Seysara usually retails for about $1,426.54 but with a SingleCare coupon for Seysara or a discount card your could pay just $1,063.81 for your Seysara prescription refill.
Medicare does not typically cover Seysara. If you are looking to save on your out-of-pocket costs for Seysara you can use SingleCare's free Seysara coupons. The average retail price of Seysara is about $1,426.54 but with our savings card you could pay the reduced price of Seysara when you refill your prescription. You can ask your pharmacist to help you compare prices to find the best one.
Seysara is a brand-name prescription drug. The ingredient in Seysara is sarecycline, but there are currently no generic versions of this medication available on the U.S. market. However, another brand-name product similar to Seysara is Oracea. Oracea is also in the tetracycline family of medications.
Seysara is a tetracycline-class drug that is used to treat moderate to severe acne vulgaris in children and adults. Seysara is a once-daily oral tablet that can be used in patients who are at least nine years old. This medication will not treat viral infections like the flu or common cold.
You should not use Seysara if you are allergic to any of its ingredients or other antibiotics like doxycycline, minocycline, tetracycline, or tigecycline. You should only use Seysara as prescribed by your healthcare provider. You can take this medication with or without food; be sure to take it with plenty of liquid. Do not stop taking this medication before the prescribed length of time, even your acne is better, as skipping doses can increase your risk of bacteria that is resistant to Seysara. Ask your prescriber when you can stop taking Seysara.
Before using Seysara, you should tell your doctor about other medical conditions you may have and medications you are taking including prescription drugs, over-the-counter medications, vitamins, and herbal supplements.
Seysara increases the possibility of sunburn, so try to avoid the sun while taking this medicine. If you are in the sun, wear protective clothing and a hat as well as sunscreen, and minimize time in the sun. Also, while taking Seysara, drink plenty of fluids to lower the risk of esophageal problems.
If you are pregnant or become pregnant while using Seysara you need to tell your doctor. Taking this medication during your pregnancy can affect your unborn baby's teeth and bone development. Seysara can also cause permanent tooth discoloration in your baby later in life. You should not breastfeed while using this medication as it can pass through your breast milk and can affect your baby's teeth and bone development.
The most common side effect of Seysara is nausea. However, other side effects can occur. You can get more information about this medication from your doctor or pharmacist. You can also report other side effects to the FDA.
After receiving her doctorate from the University of Pittsburgh School of Pharmacy, Karen Berger, Pharm.D., has worked in both chain and independent community pharmacies. She currently works at an independent pharmacy in New Jersey. Dr. Berger enjoys helping patients understand medical conditions and medications—both in person as a pharmacist, and online as a medical writer and reviewer.
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SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved