Synjardy is a diabetes medication used (in addition to diet and exercise) to control blood sugar in patients with Type 2 diabetes. It can also be used to lower the risk of cardiovascular death in adults with both Type 2 diabetes and heart disease. The average Synjardy price is around $849.00 for 60, 12.5-1000mg tablets, but you can use SingleCare Synjardy coupons to lower this cost to approximately $516.95 for 60, 12.5-1000mg tablets. You can also use SingleCare discount coupons to lower other prescription medication costs by 80%.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 12/05/2025
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Synjardy is a diabetes medication used (in addition to diet and exercise) to control blood sugar in patients with Type 2 diabetes. It can also be used to lower the risk of cardiovascular death in adults with both Type 2 diabetes and heart disease. The average Synjardy price is around $849.00 for 60, 12.5-1000mg tablets, but you can use SingleCare Synjardy coupons to lower this cost to approximately $516.95 for 60, 12.5-1000mg tablets. You can also use SingleCare discount coupons to lower other prescription medication costs by 80%.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Synjardy Retail Price | Synjardy SingleCare Price |
|---|---|---|
| CVS Pharmacy | $741.60 | $568.80 |
| Walmart | $755.40 | $585.60 |
| Walgreens | $721.20 | $669.00 |
| Kroger Pharmacy | $755.40 | $518.40 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Synjardy is a diabetes medication used (in addition to diet and exercise) to control blood sugar in patients with Type 2 diabetes. It can also be used to lower the risk of cardiovascular death in adults with both Type 2 diabetes and heart disease. The average Synjardy price is around $849.00 for 60, 12.5-1000mg tablets, but you can use SingleCare Synjardy coupons to lower this cost to approximately $516.95 for 60, 12.5-1000mg tablets. You can also use SingleCare discount coupons to lower other prescription medication costs by 80%.
$849.00 for 60, 12.5-1000mg tablets is the average cash price of a one-month supply of Synjardy without insurance. You can save greatly on Synjardy by signing up for a SingleCare savings card and paying as little as $516.95 for 60, 12.5-1000mg tablets to refill your prescription at participating pharmacies.
Various health insurance plans have different pricing for Synjardy. You may need to request an accurate price with your insurance from your pharmacist or insurance company. SingleCare allows you to purchase Synjardy at an affordable rate of $516.95 for 60, 12.5-1000mg tablets. This may work out to be even cheaper than getting Synjardy through your insurance plan. Search for Synjardy coupons on the Singlecare website or mobile app to compare prices and get a discount today.
Synjardy costs with Medicare will vary by plan, prescription, and coverage stage. Refer to your plan’s drug formulary to find out whether your Medicare Part D or Medicare Advantage plan covers Synjardy and how much the copay or coinsurance is. Purchasing Synjardy with a SingleCare card may cost less than with Medicare prescription coverage. Ask your pharmacist to process your SingleCare discount card when you drop off your prescription to find the lowest price of Synjardy.
You can use a Synjardy free coupon from SingleCare to save on your next Synjardy prescription refill. With a free drug coupon from SingleCare, you could pay as low as $516.95 for 60, 12.5-1000mg tablets for Synjardy.
Boehringer Ingelheim Pharmaceuticals, Inc. is the manufacturer of Synjardy. No generic version of Synjardy is currently available. For savings on the cost of Synjardy, use SingleCare's savings card and pay just $516.95 for 60, 12.5-1000mg tablets.
Synjardy is an FDA-approved brand-name prescription drug used along with diet and exercise to control blood sugar in patients with Type 2 diabetes. It is an oral medication that contains a combination of empagliflozin and metformin. Synjardy works by helping your kidneys get rid of sugar in the urine and lowering glucose production in the liver. It is used along with exercise and diet to improve blood sugar levels in adults. Note: Synjardy is not meant to treat Type 1 diabetes or diabetic ketoacidosis.
Synjardy is available in 5-500 mg tablets, 12.5-500 mg tablets, 12.5-1000 mg tablets, and 5-1000 mg tablets. Synjardy should be taken by mouth, usually twice a day with meals. A lower dose may be used at the beginning of treatment to avoid immediate side effects. Before taking Synjardy, carefully read the prescription label and medication guide, and check with your doctor for medical advice if you have any questions or concerns.
Synjardy XR is also available, as an extended-release tablet. It is taken once daily.
Common side effects of Synjardy include nausea, vomiting, diarrhea, gas, indigestion, stomach discomfort, urinary tract infection (UTI), weakness, headache, joint pain, metallic taste in the mouth, and appetite loss.
Synjardy may induce ovulation, which can increase the chance of pregnancy. Talk to your healthcare provider about effective birth control options if you do not want to become pregnant. If you become pregnant while taking Synjardy, tell your healthcare provider right away.
Synjardy may cause serious infections around the genital or rectal area. Seek medical attention right away if you experience adverse effects such as burning, itching, odor, discharge, pain, tenderness, swelling, or redness around the genitals or rectum, or if you have a fever.
Allergic reactions are rare. If you have symptoms of an allergic reaction, such as hives, trouble breathing, or swelling of the face, lips, tongue, or throat, seek emergency medical help right away.
This is not a full list of side effects, and others may occur. Talk to your healthcare provider about other possible side effects before using Synjardy.
Synjardy is not appropriate for everyone. Before taking Synjardy, tell your healthcare provider about all of your medical conditions, medical history, and family history. Individuals who should not take Synjardy include:
People who are allergic to empagliflozin, metformin, or any ingredient in Synjardy
People with severe kidney problems or end-stage renal disease or on dialysis
People who are in metabolic acidosis or diabetic ketoacidosis
Women who are pregnant or breastfeeding
People with type 1 diabetes
People who are volume depleted or dehydrated
People with liver disease
Before taking Synjardy, tell your healthcare provider about any allergies to medications, as well as all the medications you take, including Rx and OTC drugs, vitamins, and supplements. Some examples of drug interactions with Synjardy include:
Alcohol
Demadex (torsemide)
Diamox (acetazolamide)
Dilantin (phenytoin)
Glipizide, glimepiride, glyburide
Hydrochlorothiazide
Insulin
Invokana (canagliflozin)
Lasix (furosemide)
Lithium
Oral contraceptives (birth control pills)
Prednisone
Ranexa (ranolazine)
Steglatro (ertugliflozin)
Synthroid (levothyroxine)
Tagamet (cimetidine)
Topamax (topiramate)
Zonegran (zonisamide)
This is not a full list of drug interactions. Other interactions may occur. Consult your doctor for a full list of drug interactions.
If you are looking to change to a Synjardy alternative, contact your healthcare provider. Only your healthcare provider can determine which drug is appropriate for you.
There are different diabetes medications in several drug classes. These include single-ingredient drugs (such as Januvia, Jardiance, or metformin), multiple-ingredient drugs (such as Oseni, Janumet, or Xigduo XR), or injectable medications (such as Ozempic, Trulicity, or Victoza). Your healthcare provider can give you additional information and review various drugs with you to determine which one would be most appropriate if you need an alternative to Synjardy.
After receiving her doctorate from the University of Pittsburgh School of Pharmacy, Karen Berger, Pharm.D., has worked in both chain and independent community pharmacies. She currently works at an independent pharmacy in New Jersey. Dr. Berger enjoys helping patients understand medical conditions and medications—both in person as a pharmacist, and online as a medical writer and reviewer.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved