Solu-Cortef is a brand-name prescription injection with hydrocortisone that is administered when oral hydrocortisone is not possible or sufficient. Solu-Cortef is administered by a healthcare professional as an intravenous infusion, intravenous injection, or intravenous infusion. The prescription price for Solu-Cortef is $32.73 for 1, 100mg solution reconstituted. A SingleCare Solu-Cortef coupon, however, reduces that cost significantly to $15.03 if the hospital or clinic where you receive your infusion or injection will accept SingleCare.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 05/05/2026
Solu-Cortef is a brand-name prescription injection with hydrocortisone that is administered when oral hydrocortisone is not possible or sufficient. Solu-Cortef is administered by a healthcare professional as an intravenous infusion, intravenous injection, or intravenous infusion. The prescription price for Solu-Cortef is $32.73 for 1, 100mg solution reconstituted. A SingleCare Solu-Cortef coupon, however, reduces that cost significantly to $15.03 if the hospital or clinic where you receive your infusion or injection will accept SingleCare.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Solu-Cortef Retail Price | Hydrocortisone Sod Suc (Pf) Retail Price | Hydrocortisone Sod Suc (Pf) SingleCare Price |
|---|---|---|---|
| CVS Pharmacy | $37.99 | - | - |
| Walmart | $30.05 | - | - |
| Walgreens | $75.79 | $18.99 | $18.23 |
| Kroger Pharmacy | $30.30 | $18.99 | $18.03 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Solu-Cortef is a brand-name prescription injection with hydrocortisone that is administered when oral hydrocortisone is not possible or sufficient. Solu-Cortef is administered by a healthcare professional as an intravenous infusion, intravenous injection, or intravenous infusion. The prescription price for Solu-Cortef is $32.73 for 1, 100mg solution reconstituted. A SingleCare Solu-Cortef coupon, however, reduces that cost significantly to $15.03 if the hospital or clinic where you receive your infusion or injection will accept SingleCare.
Solu-Cortef costs $32.73 for 1, 100mg solution reconstituted at full price. A SingleCare Solu-Cortef coupon, however, lowers the price of Solu-Cortef to $15.03 if the hospital or clinic where you receive Solu-Cortef injections or infusions will accept SingleCare.
Insurance copays for Solu-Cortef, like any other prescription drug, depend on your insurance plan and the dosage prescribed. With SingleCare, Solu-Cortef costs as little as $15.03 for 1, 100mg solution reconstituted, which might beat your insurance copay if the hospital or clinic where you receive Solu-Cortef injections or infusions will accept SingleCare.
Solu-Cortef is usually not covered by Medicare Advantage or Medicare Part D prescription drug plans, but may be covered under Medicare Part B. Patients without Solu-Cortef coverage could pay only $15.03 for 1, 100mg solution reconstituted if the hospital or clinic where Solu-Cortef injections or infusions are given will accept SingleCare.
Solu-Cortef is a brand-name prescription injection with hydrocortisone injection. There is no generic alternative available at this time.
Solu-Cortef is a brand-name prescription hydrocortisone infusion or injection used when oral administration is not sufficient to address the condition. These conditions include active episodes of multiple sclerosis, severe allergic reactions, severe asthma, severe skin reactions to drugs, respiratory illnesses, swelling caused by tubercular meningitis or trichinosis, swelling in the brain, and similar conditions. Solu-Cortef is also used to relieve symptoms in patients with leukemia or lymphoma and to induce urination in people with proteinuria, a condition in which there is a high amount of protein in the urine.
Solu-Cortef is also used as an emergency hormone replacement therapy in patients with adrenal insufficiency. The adrenal gland produces a hormone nearly identical to hydrocortisone. Solu-Cortef replaces that hormone in an urgent situation.
Solu-Cortef is a corticosteroid, a family of drugs that reduces swelling by blocking the immune system's ability to release chemicals that cause swelling.
Solu-Cortef is administered as an intravenous infusion, intravenous injection, or intramuscular injection by a healthcare professional. It is not intended for continuous corticosteroid treatment, so the patient will be transitioned to a simpler injection or an oral corticosteroid.
The most common side effects of Solu-Cortef include but are not limited to acne, stomach upset, headache, dizziness, insomnia, increased appetite, weight gain, fluid retention, and menstrual changes. Many patients will experience injection site reactions such as pain, swelling, or redness. The active ingredient in Solu-Cortef, hydrocortisone, may cause mood swings. Allergic reactions are rare, but discontinue Solu-Cortef at any sign of an allergic reaction, such as rash, hives, or trouble breathing.
This is not a complete list of side effects. Consult with your doctor or pharmacist if you have concerns or questions about possible side effects of Solu-Cortef.
SingleCare is accepted at most national pharmacies and grocers, including the following:
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SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2026 SingleCare Administrators. All rights reserved