Oral routeThis medicine may cause birth defects if either partner is using it during conception or pregnancy. Tell your doctor right away if you or your partner becomes pregnant. If you are a woman who can get pregnant, your doctor may do tests to make sure you are not pregnant before starting treatment. Use an effective form of birth control to keep from getting pregnant during treatment and for at least 4 weeks after the last dose. Males who are taking this medicine, with female partners who can become pregnant must use effective birth control during treatment and for at least 7 weeks after the last dose.
Do not breastfeed during treatment with this medicine and for at least 4 weeks after the last dose.
Tell your doctor if you have kidney disease, liver disease, bleeding problems, dental problems, diabetes, thyroid problems, or a history of seizures. Tell your doctor if you have heart disease, heart failure, heart rhythm problems, high blood pressure, or a history of heart attack. Tell your doctor if you recently had any severe infection, trauma, or surgery, including dental surgery.
Oral routeMedicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.
This medicine may cause the following problems:Liver problemsHeart problems (including heart attack, heart failure, heart rhythm problems, high blood pressure, cardiomyopathy)Increased risk of bleedingTumor lysis syndrome (electrolyte and metabolic problems that can be life-threatening)Thrombotic microangiopathy (blood vessel damage)Serious skin reactions (including erythema multiforme, Stevens-Johnson syndrome, necrotizing fasciitis, and toxic epidermal necrolysis)Reversible posterior leukoencephalopathy syndrome (brain problem)Thyroid problems (including hyperthyroidism or hypothyroidism)Hypoglycemia (low blood sugar)Jaw problems
Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests. This medicine can cause slow wound healing.
Oral routeThis medicine could cause infertility. Talk with your doctor before using this medicine if you plan to have children.
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Keep all medicine out of the reach of children. Never share your medicine with anyone.
Numbness or weakness in your arm or leg, pain in your lower leg, sudden or severe headache, problems with vision, speech, or walking
Rapid weight gain, swelling in your hands, ankles, or feet
Shaking, trembling, sweating, fast or pounding heartbeat, lightheadedness, hunger, confusion
