lisinopril, an angiotensin-converting enzyme (ACE) inhibitor, and hydrochlorothiazide, a diuretic. Lisinopril-HCTZ works by relaxing blood vessels and reducing the amount of water in the body, allowing blood to flow more easily and efficiently. Brand names of Lisinopril-HCTZ include Prinzide and Zestoretic. The average retail price of Lisinopril-HCTZ is $36.33 for 30, 20-12.5mg tablets. With a SingleCare Lisinopril-HCTZ coupon, the retail price could be reduced to $2.88 for 30, 20-12.5mg tablets at participating pharmacies.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 12/05/2025
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lisinopril, an angiotensin-converting enzyme (ACE) inhibitor, and hydrochlorothiazide, a diuretic. Lisinopril-HCTZ works by relaxing blood vessels and reducing the amount of water in the body, allowing blood to flow more easily and efficiently. Brand names of Lisinopril-HCTZ include Prinzide and Zestoretic. The average retail price of Lisinopril-HCTZ is $36.33 for 30, 20-12.5mg tablets. With a SingleCare Lisinopril-HCTZ coupon, the retail price could be reduced to $2.88 for 30, 20-12.5mg tablets at participating pharmacies.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Lisinopril-Hydrochlorothiazide Retail Price | Lisinopril-Hydrochlorothiazide SingleCare Price |
|---|---|---|
| CVS Pharmacy | $17.70 | $17.40 |
| Walmart | $7.20 | $6.00 |
| Walgreens | $20.98 | $11.40 |
| Kroger Pharmacy | $16.78 | $3.29 |
| Albertsons Pharmacy | $28.31 | $5.10 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
lisinopril, an angiotensin-converting enzyme (ACE) inhibitor, and hydrochlorothiazide, a diuretic. Lisinopril-HCTZ works by relaxing blood vessels and reducing the amount of water in the body, allowing blood to flow more easily and efficiently. Brand names of Lisinopril-HCTZ include Prinzide and Zestoretic. The average retail price of Lisinopril-HCTZ is $36.33 for 30, 20-12.5mg tablets. With a SingleCare Lisinopril-HCTZ coupon, the retail price could be reduced to $2.88 for 30, 20-12.5mg tablets at participating pharmacies.
Without insurance, the average cost of Lisinopril-HCTZ is $36.33 for 30, 20-12.5mg tablets. However, retail prices can vary based on the pharmacy location and the quantity prescribed. Consult your pharmacy to determine the cost of your prescription. Using prescription discount cards like the one from SingleCare may help lower the cost of this medication to $2.88 for 30, 20-12.5mg tablets. SingleCare may be able to reduce your prescription drug prices by up to 80%.
The cost of Lisinopril-HCTZ with insurance varies by insurance plan and the quantity prescribed, among other factors. Insurance plans will usually help cover the cost of Lisinopril-HCTZ because it’s a generic medication. However, you may be responsible for a copay or coinsurance amount, depending on your coverage stage. Consult your insurance plan or pharmacist for more information about the cost of Lisinopril-HCTZ with your plan. You could save more money with SingleCare than you would with insurance, so have your pharmacist compare prices.
Medicare coverage will vary by plan, prescription, and coverage stage. Refer to your plan’s drug formulary to find out whether your Medicare Part D or Medicare Advantage plan covers Lisinopril-HCTZ. Patients without Medicare coverage can use a SingleCare Lisinopril-HCTZ coupon to get the lowest prices. The current lowest price with SingleCare is $2.88 for 30, 20-12.5mg tablets.
Yes, Lisinopril-HCTZ is a generic combination drug that contains lisinopril and hydrochlorothiazide. The brand-name equivalent of Lisinopril-HCTZ is Zestoretic, which may be more expensive than the generic version. You can search the SingleCare website or app for potential savings on both the generic and brand-name versions of this medication.
Lisinopril-HCTZ is a combination medication used to treat high blood pressure, a chronic condition that can lead to serious health problems if left untreated. In severe cases, high blood pressure may contribute to heart failure, kidney disease, stroke, and heart attacks.
Lisinopril-HCTZ works by combining the effects of an angiotensin-converting enzyme (ACE) inhibitor, lisinopril, and a diuretic, hydrochlorothiazide. Lisinopril helps to relax blood vessels, allowing blood to flow more easily and reducing the strain on the heart. Hydrochlorothiazide helps remove excess water and salt from the body through increased urine production, lowering blood pressure. Together, these drugs effectively manage high blood pressure.
Lisinopril-HCTZ is available in various strengths, combining different dosages of lisinopril and hydrochlorothiazide. These strengths include:
Lisinopril 10 mg / Hydrochlorothiazide 12.5 mg
Lisinopril 20 mg / Hydrochlorothiazide 12.5 mg
Lisinopril 20 mg / Hydrochlorothiazide 25 mg
Your healthcare provider will determine the appropriate dosage of Lisinopril-HCTZ based on your medical condition, response to treatment, and other factors. It is important to follow your doctor's instructions and take the medication as prescribed. Do not change the dosage or discontinue the medication without consulting your doctor.
Common side effects of Lisinopril-HCTZ may include:
Dizziness
Headache
Fatigue
Cough
Nausea
Dehydration
Serious side effects of Lisinopril-HCTZ can occur, including low blood pressure, kidney problems, and allergic reactions. If you experience any severe side effects, such as difficulty breathing, swelling of the face or throat, or a severe rash, seek medical help immediately.
It is important to consult a healthcare provider for other potential precautions or warnings related to the use of Lisinopril-HCTZ. This list of side effects is not exhaustive, and your doctor or pharmacist can provide more information about possible side effects and drug interactions.
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