lisinopril, an angiotensin-converting enzyme (ACE) inhibitor, and hydrochlorothiazide, a diuretic. Lisinopril-HCTZ works by relaxing blood vessels and reducing the amount of water in the body, allowing blood to flow more easily and efficiently. Brand names of Lisinopril-HCTZ include Prinzide and Zestoretic. The average retail price of Lisinopril-HCTZ is $36.79 for 30, 20-12.5mg tablets. With a SingleCare Lisinopril-HCTZ coupon, the retail price could be reduced to $2.54 for 30, 20-12.5mg tablets at participating pharmacies.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 05/05/2026
lisinopril, an angiotensin-converting enzyme (ACE) inhibitor, and hydrochlorothiazide, a diuretic. Lisinopril-HCTZ works by relaxing blood vessels and reducing the amount of water in the body, allowing blood to flow more easily and efficiently. Brand names of Lisinopril-HCTZ include Prinzide and Zestoretic. The average retail price of Lisinopril-HCTZ is $36.79 for 30, 20-12.5mg tablets. With a SingleCare Lisinopril-HCTZ coupon, the retail price could be reduced to $2.54 for 30, 20-12.5mg tablets at participating pharmacies.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Lisinopril-Hydrochlorothiazide Retail Price | Lisinopril-Hydrochlorothiazide SingleCare Price |
|---|---|---|
| CVS Pharmacy | $17.70 | $17.40 |
| Walmart | $7.82 | $5.70 |
| Walgreens | $21.00 | $14.10 |
| Kroger Pharmacy | $16.80 | $3.21 |
| Albertsons Pharmacy | $16.89 | $5.34 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
lisinopril, an angiotensin-converting enzyme (ACE) inhibitor, and hydrochlorothiazide, a diuretic. Lisinopril-HCTZ works by relaxing blood vessels and reducing the amount of water in the body, allowing blood to flow more easily and efficiently. Brand names of Lisinopril-HCTZ include Prinzide and Zestoretic. The average retail price of Lisinopril-HCTZ is $36.79 for 30, 20-12.5mg tablets. With a SingleCare Lisinopril-HCTZ coupon, the retail price could be reduced to $2.54 for 30, 20-12.5mg tablets at participating pharmacies.
Without insurance, the average cost of Lisinopril-HCTZ is $36.79 for 30, 20-12.5mg tablets. However, retail prices can vary based on the pharmacy location and the quantity prescribed. Consult your pharmacy to determine the cost of your prescription. Using prescription discount cards like the one from SingleCare may help lower the cost of this medication to $2.54 for 30, 20-12.5mg tablets. SingleCare may be able to reduce your prescription drug prices by up to 80%.
The cost of Lisinopril-HCTZ with insurance varies by insurance plan and the quantity prescribed, among other factors. Insurance plans will usually help cover the cost of Lisinopril-HCTZ because it’s a generic medication. However, you may be responsible for a copay or coinsurance amount, depending on your coverage stage. Consult your insurance plan or pharmacist for more information about the cost of Lisinopril-HCTZ with your plan. You could save more money with SingleCare than you would with insurance, so have your pharmacist compare prices.
Medicare coverage will vary by plan, prescription, and coverage stage. Refer to your plan’s drug formulary to find out whether your Medicare Part D or Medicare Advantage plan covers Lisinopril-HCTZ. Patients without Medicare coverage can use a SingleCare Lisinopril-HCTZ coupon to get the lowest prices. The current lowest price with SingleCare is $2.54 for 30, 20-12.5mg tablets.
Yes, Lisinopril-HCTZ is a generic combination drug that contains lisinopril and hydrochlorothiazide. The brand-name equivalent of Lisinopril-HCTZ is Zestoretic, which may be more expensive than the generic version. You can search the SingleCare website or app for potential savings on both the generic and brand-name versions of this medication.
Lisinopril-HCTZ is a combination medication used to treat high blood pressure, a chronic condition that can lead to serious health problems if left untreated. In severe cases, high blood pressure may contribute to heart failure, kidney disease, stroke, and heart attacks.
Lisinopril-HCTZ works by combining the effects of an angiotensin-converting enzyme (ACE) inhibitor, lisinopril, and a diuretic, hydrochlorothiazide. Lisinopril helps to relax blood vessels, allowing blood to flow more easily and reducing the strain on the heart. Hydrochlorothiazide helps remove excess water and salt from the body through increased urine production, lowering blood pressure. Together, these drugs effectively manage high blood pressure.
Lisinopril-HCTZ is available in various strengths, combining different dosages of lisinopril and hydrochlorothiazide. These strengths include:
Lisinopril 10 mg / Hydrochlorothiazide 12.5 mg
Lisinopril 20 mg / Hydrochlorothiazide 12.5 mg
Lisinopril 20 mg / Hydrochlorothiazide 25 mg
Your healthcare provider will determine the appropriate dosage of Lisinopril-HCTZ based on your medical condition, response to treatment, and other factors. It is important to follow your doctor's instructions and take the medication as prescribed. Do not change the dosage or discontinue the medication without consulting your doctor.
Common side effects of Lisinopril-HCTZ may include:
Dizziness
Headache
Fatigue
Cough
Nausea
Dehydration
Serious side effects of Lisinopril-HCTZ can occur, including low blood pressure, kidney problems, and allergic reactions. If you experience any severe side effects, such as difficulty breathing, swelling of the face or throat, or a severe rash, seek medical help immediately.
It is important to consult a healthcare provider for other potential precautions or warnings related to the use of Lisinopril-HCTZ. This list of side effects is not exhaustive, and your doctor or pharmacist can provide more information about possible side effects and drug interactions.
Gerardo Sison, Pharm.D., graduated from the University of Florida. He has worked in both community and hospital settings, providing drug information and medication therapy management services. As a medical writer, he hopes to educate and empower patients to better manage their health and navigate their treatment plans.
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SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2026 SingleCare Administrators. All rights reserved