What is Symdeko: Uses, Warnings & Interactions

How to take Symdeko

• Your doctor will tell you how much medicine to use. Do not use more than directed.

• Take this medicine with food that contains fat, including cheese pizza, eggs, butter, peanut butter, or whole-milk dairy products. This helps your body absorb the medicine better.

• Oral granules: Shake the packet gently before you open it. Pour the contents into 1 teaspoon (5 milliliters) of room temperature or cold soft food or liquid (including applesauce, pureed fruits or vegetables, yogurt, water, breast milk, infant formula, milk, or juice) and mix together. Give this mixture within 1 hour and make sure all the medicine is taken. Give food that contains fat right before or right after you give the mixture.

• Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

• Missed dose: If it is 6 hours or less from the time you normally take your medicine, take a dose as soon as you can. If it is more than 6 hours, skip the missed dose and take your next dose at the regular time. Do not take extra medicine to make up for a missed dose.

• Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

• Oral granules: Shake the packet gently before you open it. Pour the contents into 1 teaspoon (5 milliliters) of room temperature or cold soft food or liquid (including applesauce, pureed fruits or vegetables, yogurt, water, breast milk, infant formula, milk, or juice) and mix together. Give this mixture within 1 hour and make sure all the medicine is taken. Give food that contains fat right before or right after you give the mixture.

• Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

• Missed dose: If it is 6 hours or less from the time you normally take your medicine, take a dose as soon as you can. If it is more than 6 hours, skip the missed dose and take your next dose at the regular time. Do not take extra medicine to make up for a missed dose.

• Take this medicine with food that contains fat, including cheese pizza, eggs, butter, peanut butter, or whole-milk dairy products. This helps your body absorb the medicine better.

• Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

• Your doctor will tell you how much medicine to use. Do not use more than directed.

• Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

• Your doctor will tell you how much medicine to use. Do not use more than directed.

• Swallow the tablets whole. Do not crush, break, or chew them.

• Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

• Take this medicine with food that contains fat, including food prepared with butter or oils, cheese, eggs, meat, nuts, or whole milk. This helps your body absorb the medicine better.

• Missed dose: If it is 6 hours or less from the time you normally take your medicine, take a dose as soon as you can. If it is more than 6 hours, skip the missed dose and take your next dose at the regular time. Do not take extra medicine to make up for a missed dose.

• Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

• Take this medicine with food that contains fat, including food prepared with butter or oils, cheese, eggs, meat, nuts, or whole milk. This helps your body absorb the medicine better.

• Missed dose: If it is 6 hours or less from the time you normally take your medicine, take a dose as soon as you can. If it is more than 6 hours, skip the missed dose and take your next dose at the regular time. Do not take extra medicine to make up for a missed dose.

• Swallow the tablets whole. Do not crush, break, or chew them.

• Your doctor will tell you how much medicine to use. Do not use more than directed.

• Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

What to do if you miss a dose of Symdeko

Symdeko contraindications

• This medicine is not right for everyone. Do not use it if you had an allergic reaction to ivacaftor.

• This medicine is not right for everyone. Do not use it if you had an allergic reaction to tezacaftor or ivacaftor.

Symdeko warnings

• Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

• Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, or if you have ever been exposed to radiation.

• This medicine may cause dizziness. Do not drive or do anything else that could be dangerous unless you know how this medicine affects you.

• Keep all medicine out of the reach of children. Never share your medicine with anyone.

• This medicine may cause the following problems:Liver problemsCataracts

• Keep all medicine out of the reach of children. Never share your medicine with anyone.

• Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, or eye or vision problems (including cataracts).

• This medicine may make you dizzy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

• Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Symdeko interactions

• Some foods and medicines can affect how ivacaftor works. Tell your doctor if you are using any of the following: Carbamazepine, clarithromycin, cyclosporine, digoxin, erythromycin, fluconazole, glimepiride, glipizide, itraconazole, ketoconazole, oral midazolam, phenobarbital, phenytoin, posaconazole, rifabutin, rifampin, St John's wort, tacrolimus, telithromycin, voriconazole, warfarin

• Do not eat or drink anything that contains grapefruit or Seville oranges.

• Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

• Keep all medicine out of the reach of children. Never share your medicine with anyone.

• Do not use this medicine together with carbamazepine, rifabutin, rifampin, phenobarbital, phenytoin, or St John€™s wort.

• Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

• Some medicines may affect how tezacaftor/ivacaftor and ivacaftor works. Tell your doctor if you are using any of the following:Clarithromycin, cyclosporine, digoxin, erythromycin, everolimus, fluconazole, itraconazole, ketoconazole, posaconazole, sirolimus, tacrolimus, telithromycin, voriconazoleSteroid medicine