Symfi is a lower-priced generic prescription combination drug used to control the underlying viral infection that causes HIV/AIDS. Symfi combines three prescription drugs – efavirenz, lamivudine, and tenofovir – that reduce the amount of HIV in the body by preventing the virus from making copies of itself. Symfi's retail price is $1,997.38, but you can get a discount and pay $556.04 with a SingleCare Symfi coupon. SingleCare coupons are honored at many local pharmacies, like CVS, Walmart, Kroger, and Walgreens. Read the FAQs for more information about how much Symfi costs, how it works, possible side effects, and how you can save money on your Symfi prescription.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 01/19/2026
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Symfi is a lower-priced generic prescription combination drug used to control the underlying viral infection that causes HIV/AIDS. Symfi combines three prescription drugs – efavirenz, lamivudine, and tenofovir – that reduce the amount of HIV in the body by preventing the virus from making copies of itself. Symfi's retail price is $1,997.38, but you can get a discount and pay $556.04 with a SingleCare Symfi coupon. SingleCare coupons are honored at many local pharmacies, like CVS, Walmart, Kroger, and Walgreens. Read the FAQs for more information about how much Symfi costs, how it works, possible side effects, and how you can save money on your Symfi prescription.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Symfi is a lower-priced generic prescription combination drug used to control the underlying viral infection that causes HIV/AIDS. Symfi combines three prescription drugs – efavirenz, lamivudine, and tenofovir – that reduce the amount of HIV in the body by preventing the virus from making copies of itself. Symfi's retail price is $1,997.38, but you can get a discount and pay $556.04 with a SingleCare Symfi coupon. SingleCare coupons are honored at many local pharmacies, like CVS, Walmart, Kroger, and Walgreens. Read the FAQs for more information about how much Symfi costs, how it works, possible side effects, and how you can save money on your Symfi prescription.
Uninsured customers pay an average of $1,997.38, but Symfi prices can vary. Visit a nearby participating pharmacy and pay only $556.04 with a SingleCare Symfi coupon. Your SingleCare discount card can reduce your prescription drug prices up to 80%.
Uninsured patients, however, can find help for some or all of Symfi's cost from ADAP (AIDS Drug Assistance Program). The HarborPath ADAP Waiting List Program may be able to help patients with their Symfi prescription when state ADAP funding falls short.
Symfi is usually covered by Medicare prescription drug plans. Patients without Medicare prescription drug coverage or who can't afford the copay have many Symfi patient assistance resources available, including ADAP, HarborPath, and other programs. For those who still cannot affordably fill their prescription, consider using a SingleCare Symfi coupon. With a SingleCare discount card, the price of Symfi could be just $556.04 for 30, 600-300-300mg tablets.
Symfi is usually covered by Medicare prescription drug plans. Patients without Medicare prescription drug coverage or who can't afford the copay have many Symfi patient assistance resources available, including ADAP, HarborPath, and other programs. For those who still cannot affordably fill their prescription, consider using a SingleCare Symfi coupon. With a SingleCare discount card, the price of Symfi could be just $556.04 for 30, 600-300-300mg tablets.
Symfi is a lower-cost generic drug with the active ingredients efavirenz, lamivudine, and tenofovir. There are no generic or brand-name alternatives to Symfi.
Symfi is a brand-name prescription combination drug used to control the underlying viral infection that causes HIV/AIDS. Symfi combines three prescription drugs – efavirenz, lamivudine, and tenofovir disoproxil fumarate – that reduce HIV in the body by blocking a critical protein that HIV needs to make copies of itself.
HIV targets the body's immune system. As the infection progresses, patients become vulnerable to serious and ultimately life-threatening secondary infections and cancers. Symfi reduces the amount of HIV in the body and gives the immune system the chance to recover.
Symfi is taken as a fixed-dose tablet once a day on an empty stomach and preferably at bedtime. Symfi is not prescribed to patients with kidney failure, liver damage, or a hepatitis B infection.
The most common side effects of Symfi are headache, dizziness, feeling tired, nausea, vomiting, diarrhea, cough, and pain. A number of serious side effects are associated with Symfi including liver damage, kidney impairment, pancreas problems, nervous system problems, and a potentially lethal buildup of lactic acid in the body (lactic acidosis).
Mental and mood changes include trouble concentrating, depression, and abnormal dreams. Serious psychiatric side effects are also associated with Symfi and include severe depression, suicidal thoughts, suicidal attempts, aggression, paranoia, and mania. Allergic reactions are rare but can include Stevens-Johnson syndrome, a dangerous and potentially fatal skin reaction. Discontinue Symfi if any allergic symptoms, such as rash, swelling, or trouble breathing, are experienced.
This is not a complete list of side effects. Your physician will address your questions and concerns regarding potential side effects.
SingleCare is accepted at most national pharmacies and grocers, including the following:
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