Syntherma Plus Coupons & Prices

Syntherma Plus is a Topical Anesthetic Combinations class drug produced by V2 Pharma. The typical retail price of Syntherma Plus is $5,505.99 per 1, 1 kit box, but you can pay just $3,725.62 for 1, 1 kit box of Syntherma Plus when you use your SingleCare card.

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Syntherma Plus coupon at CVS Pharmacy
$3728.62
$ 3,726
$3 off with signupwith signup

Show this free card to your pharmacist.

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Syntherma Plus coupon at Kroger Pharmacy
$3737.70
$ 3,735
$3 off with signupwith signup

Save an extra $3 on any eligible prescription! Sign up for free

Members can save even more
and it's free to join

Syntherma Plus coupon at Harris Teeter Pharmacy
$3737.70
$ 3,735
$3 off with signupwith signup
Syntherma Plus coupon at Food Lion Pharmacy
$ 3,901
Syntherma Plus coupon at Publix Pharmacy
$3992.60
$ 3,990
$3 off with signupwith signup
Syntherma Plus coupon at Walmart Neighborhood Market Pharmacy
$4013.01
$ 4,010
$3 off with signupwith signup
$4013.01
$ 4,010
$3 off with signupwith signup
$4035.40
$ 4,032
$3 off with signupwith signup
$4048.60
$ 4,046
$3 off with signupwith signup

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 12/05/2025

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with the free SingleCare app.
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About Syntherma Plus

Syntherma Plus is a Topical Anesthetic Combinations class drug produced by V2 Pharma. The typical retail price of Syntherma Plus is $5,505.99 per 1, 1 kit box, but you can pay just $3,725.62 for 1, 1 kit box of Syntherma Plus when you use your SingleCare card.

About Syntherma Plus

Syntherma Plus is a Topical Anesthetic Combinations class drug produced by V2 Pharma. The typical retail price of Syntherma Plus is $5,505.99 per 1, 1 kit box, but you can pay just $3,725.62 for 1, 1 kit box of Syntherma Plus when you use your SingleCare card.

Syntherma Plus FAQs

How much is Syntherma Plus with SingleCare?

Syntherma Plus costs $3,725.62 for 1, 1 kit box with a free Syntherma Plus coupon from SingleCare.  But, you could reduce this cost more depending on your Rx information. Use the dropdown menu above to update your Rx details (i.e., brand/generic, quantity, form, dosage) to get the most accurate prices of Syntherma Plus with SingleCare at a pharmacy near you.

How much does Syntherma Plus cost without insurance?

The normal cash cost of Syntherma Plus without health insurance is $5,505.99 per 1, 1 kit box though you can save money using a SingleCare Syntherma Plus coupon to pay just $3,725.62 for 1, 1 kit box of Syntherma Plus. Those without health insurance can always use SingleCare for free Syntherma Plus savings.

How much does Syntherma Plus cost with insurance?

Each individual insurance program is distinct and may or may not cover Syntherma Plus. The cost of Syntherma Plus with insurance coverage varies depending on your plan - check with your insurance carrier for definitive drug coverage and copay specifics. If your insurance does not cover Syntherma Plus, you can use a SingleCare card to save money on Syntherma Plus at your local pharmacy. Additionally, you can also use SingleCare cards if you have Medicare or Medicaid. If Medicare or Medicaid doesn’t cover your Syntherma Plus prescription, you can use SingleCare instead. Visit the SingleCare website or app to review the lowest price of Syntherma Plus with SingleCare versus your Syntherma Plus price with insurance or Medicare.

Is generic Syntherma Plus available?

Syntherma Plus is a branded drug created by V2 Pharma. There is no generic version of Syntherma Plus available at this time.

How to use SingleCare for Syntherma Plus

SingleCare is accepted at most national pharmacies and grocery stores, including Walgreens, Kroger, Walmart, CVS, Safeway, and more. You can text, email, print, or save your free Syntherma Plus coupon to your digital wallet and show a pharmacist at checkout. 

Where are Syntherma Plus coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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