Learn more about syntherma-plus
Syntherma Plus is a Topical Anesthetic Combinations class drug made by V2 PHARMA. The typical out-of-pocket price for Syntherma Plus is $4,212.69 per 1, 1 kit box, but you can pay $3,725.92 for 1, 1 kit box of Syntherma Plus with your SingleCare discount card.
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$3728.92
$ 3,726
$3 off with signupwith signup
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This coupon is not insurance.
$3737.70
$ 3,735
$3 off with signupwith signup
$3737.70
$ 3,735
$3 off with signupwith signup
$3946.80
$ 3,944
$3 off with signupwith signup
$3968.45
$ 3,965
$3 off with signupwith signup
$4013.01
$ 4,010
$3 off with signupwith signup
$4013.01
$ 4,010
$3 off with signupwith signup
$4035.40
$ 4,032
$3 off with signupwith signup
About SingleCare Pricing
SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 09/19/2026
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About Syntherma Plus
Syntherma Plus is a Topical Anesthetic Combinations class drug made by V2 PHARMA. The typical out-of-pocket price for Syntherma Plus is $4,212.69 per 1, 1 kit box, but you can pay $3,725.92 for 1, 1 kit box of Syntherma Plus with your SingleCare discount card.
Learn more about syntherma-plus
About Syntherma Plus
Syntherma Plus is a Topical Anesthetic Combinations class drug made by V2 PHARMA. The typical out-of-pocket price for Syntherma Plus is $4,212.69 per 1, 1 kit box, but you can pay $3,725.92 for 1, 1 kit box of Syntherma Plus with your SingleCare discount card.
Syntherma Plus FAQs
How much is Syntherma Plus with SingleCare?
Syntherma Plus costs $3,725.92 for 1, 1 kit box with a free Syntherma Plus coupon from SingleCare. However, you could pay less depending on your prescription information. Use the dropdown menu above to enter your Rx info (i.e., generic/brand, quantity, dosage, form) to get the most accurate prices of Syntherma Plus with SingleCare near you.
How much does Syntherma Plus cost without insurance?
The normal counter cost of Syntherma Plus without health insurance is $4,212.69 per 1, 1 kit box though you can save money using a SingleCare Syntherma Plus coupon to pay $3,725.92 for 1, 1 kit box of Syntherma Plus. People without access to an insurance plan can always use SingleCare for free Syntherma Plus coupons.
How much does Syntherma Plus cost with insurance?
Each specific insurance formulary is distinct and may or may not cover Syntherma Plus. The cost of Syntherma Plus with insurance coverage varies depending on your plan - contact your insurance carrier for specific formulary coverage and copay specifics. If your insurance plan does not include Syntherma Plus, you can use a SingleCare card to save on Syntherma Plus at your participating pharmacy. In addition, you can also use SingleCare savings if you have Medicare or Medicaid. When Medicare or Medicaid doesn’t cover your Syntherma Plus fill, use SingleCare instead. Use the SingleCare website or app to find the lowest cost of Syntherma Plus with SingleCare versus your Syntherma Plus price with insurance or Medicare.
Is generic Syntherma Plus available?
Syntherma Plus is a brand-name medication produced by V2 PHARMA. There is no generic form of Syntherma Plus available at this time.
How to use SingleCare for Syntherma Plus
SingleCare is accepted at most major pharmacies and grocers, including Walgreens, Kroger, Walmart, CVS, Safeway, and more. You can text, email, print, or save your free Syntherma Plus coupon to your digital wallet and show your pharmacist at checkout.
Where are Syntherma Plus coupons from SingleCare accepted?
SingleCare is accepted at most national pharmacies and grocers, including the following:
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