Syntherma Plus Coupons & Prices

Syntherma Plus is a Topical Anesthetic Combinations class drug produced by V2 Pharma. The typical retail price of Syntherma Plus is $4,212.69 per 1, 1 kit box, but you can pay $3,725.92 for 1, 1 kit box of Syntherma Plus when you use your SingleCare discount card.

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Syntherma Plus coupon at CVS Pharmacy
$3728.92
$ 3,726
$3 off with signupwith signup

Show this free card to your pharmacist.

This coupon is not insurance.
Syntherma Plus coupon at Kroger Pharmacy
$3737.70
$ 3,735
$3 off with signupwith signup
Syntherma Plus coupon at Harris Teeter Pharmacy
$3737.70
$ 3,735
$3 off with signupwith signup
Syntherma Plus coupon at Walgreens Pharmacy
$3876.85
$ 3,874
$3 off with signupwith signup
Syntherma Plus coupon at Food Lion Pharmacy
$ 3,901
Syntherma Plus coupon at Publix Pharmacy
$3946.80
$ 3,944
$3 off with signupwith signup
$4013.01
$ 4,010
$3 off with signupwith signup
$4013.01
$ 4,010
$3 off with signupwith signup
$4035.40
$ 4,032
$3 off with signupwith signup

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 03/22/2026

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4.8 average rating
About Syntherma Plus

Syntherma Plus is a Topical Anesthetic Combinations class drug produced by V2 Pharma. The typical retail price of Syntherma Plus is $4,212.69 per 1, 1 kit box, but you can pay $3,725.92 for 1, 1 kit box of Syntherma Plus when you use your SingleCare discount card.

About Syntherma Plus

Syntherma Plus is a Topical Anesthetic Combinations class drug produced by V2 Pharma. The typical retail price of Syntherma Plus is $4,212.69 per 1, 1 kit box, but you can pay $3,725.92 for 1, 1 kit box of Syntherma Plus when you use your SingleCare discount card.

Syntherma Plus FAQs

How much is Syntherma Plus with SingleCare?

Syntherma Plus costs $3,725.92 for 1, 1 kit box with a free Syntherma Plus coupon from SingleCare.  But, you could reduce this cost more depending on your Rx information. Use the dropdown menu above to update your Rx details (i.e., brand/generic, quantity, form, dosage) to get the most accurate prices of Syntherma Plus with SingleCare at a pharmacy near you.

How much does Syntherma Plus cost without insurance?

The normal cash cost of Syntherma Plus without health insurance is $4,212.69 per 1, 1 kit box though you can save money using a SingleCare Syntherma Plus coupon to pay $3,725.92 for 1, 1 kit box of Syntherma Plus. Those without an insurance plan can always use SingleCare for free Syntherma Plus discounts.

How much does Syntherma Plus cost with insurance?

Each individual insurance plan is different and may or may not cover Syntherma Plus. The cost of Syntherma Plus with insurance coverage differs based on your plan - verify with your insurance provider for explicit drug coverage and coinsurance details. If your insurance plan does not cover Syntherma Plus, you can use SingleCare to save money on Syntherma Plus at your local pharmacy. In addition, you can also use SingleCare coupons if you have Medicare or Medicaid. When Medicare or Medicaid doesn’t offer your Syntherma Plus prescription, use SingleCare instead. Use the SingleCare website or app to review the lowest cost of Syntherma Plus with SingleCare versus your Syntherma Plus copay with insurance or Medicare.

Is generic Syntherma Plus available?

Syntherma Plus is a brand-name drug created by V2 Pharma. There is no generic variant of Syntherma Plus available at this time.

How to use SingleCare for Syntherma Plus

SingleCare is accepted at most major pharmacies and grocers, including Walgreens, Kroger, Walmart, CVS, Safeway, and more. You can text, email, print, or save your free Syntherma Plus coupon to your digital wallet and show a pharmacist at the counter. 

Where are Syntherma Plus coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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