What is Synvisc: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Jan 25, 2023

Synvisc overview

BRAND NAMES:

  • Synvisc, Synvisc One

Generic Names:

  • Synvisc

Uses:

  • Treats knee pain caused by osteoarthritis.

Therapeutic Classes:

  • Cartilaginous Defect Repair Agent

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Synvisc used for?

What form(s) does Synvisc come in

  • Injectable

What are common Synvisc doses?

  • Syringe 2ml of 16mg/2ml

Common Synvisc prescriptions

  • Synvisc
    2ml of 16mg/2ml syringe

How to take Synvisc

  • Your doctor will tell you how many injections you will need. This medicine is injected into your knee joint.

  • Injection routeA nurse or other health provider will give you this medicine.

What to do if you miss a dose of Synvisc

Synvisc contraindications

  • This medicine is not right for everyone. You should not receive it if you had an allergic reaction to hyaluronan (sodium hyaluronate) products.

Synvisc warnings

  • Your doctor might have to remove fluid from your joint before injecting this medicine.

  • Tell your doctor if you are pregnant or breastfeeding, or if you have a skin disease or infection near or in your joint. Also tell your doctor if you are allergic to birds, feathers, or eggs, or if you have poor circulation or a history of blood clots in your legs.

  • Rest your knee for 48 hours after you receive this medicine. Do not do strenuous weightbearing activities, such as jogging or tennis, for at least 48 hours after your injection. Put ice on your joint if you have mild swelling.

Synvisc interactions

  • Tell your doctor if you are pregnant or breastfeeding, or if you have a skin disease or infection near or in your joint. Also tell your doctor if you are allergic to birds, feathers, or eggs, or if you have poor circulation or a history of blood clots in your legs.

  • Rest your knee for 48 hours after you receive this medicine. Do not do strenuous weightbearing activities, such as jogging or tennis, for at least 48 hours after your injection. Put ice on your joint if you have mild swelling.

  • Your doctor might have to remove fluid from your joint before injecting this medicine.

Synvisc side effects

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Severe redness, swelling, pain, or stiffness in your joint

Less Serious Side Effects

  • Mild pain, redness, or swelling where the medicine was injected

  • Mild increase in pain, swelling, or stiffness in your knee

Subscribe to our savings newsletter

Health education, drug info, wellness & more

By clicking 'Subscribe', I agree to SingleCare's Terms & Conditions.