Learn more about prempro
Prempro is a prescription medication used by women to treat menopause-related symptoms, such as hot flashes and vaginal dryness. It’s also used to prevent postmenopausal bone loss. Conjugated estrogens and medroxyprogesterone acetate are the active ingredients in Prempro. The average retail price of 1, 28 tablets of 0.3mg/1.5mg tablet of Prempro is $346.64. To lower the cost of your prescription to $230.64 for 1, 28 tablets of 0.3mg/1.5mg tablet, you can use these Prempro coupons or a SingleCare savings card at participating pharmacies near you.
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$233.64
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$233.64
$ 230.64
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$235.60
$ 232.60
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$237.92
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$240.27
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$251.49
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$ 260.56
About SingleCare Pricing
SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 12/05/2025
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About Prempro
Prempro is a prescription medication used by women to treat menopause-related symptoms, such as hot flashes and vaginal dryness. It’s also used to prevent postmenopausal bone loss. Conjugated estrogens and medroxyprogesterone acetate are the active ingredients in Prempro. The average retail price of 1, 28 tablets of 0.3mg/1.5mg tablet of Prempro is $346.64. To lower the cost of your prescription to $230.64 for 1, 28 tablets of 0.3mg/1.5mg tablet, you can use these Prempro coupons or a SingleCare savings card at participating pharmacies near you.
Learn more about prempro
Prempro Price History & Information
Price History for Prempro
1 count, disp pack, 28 tabletsOur price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
Average 1-Month Prices for Prempro
1 count, disp pack, 28 tablets| Pharmacy | Prempro Retail Price | Prempro SingleCare Price |
|---|---|---|
| CVS Pharmacy | $295.12 | $240.52 |
| Walmart | $297.08 | $235.48 |
| Walgreens | $381.92 | $240.24 |
| Kroger Pharmacy | $297.08 | $233.52 |
| Albertsons Pharmacy | $307.72 | $252.56 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
About Prempro
Prempro is a prescription medication used by women to treat menopause-related symptoms, such as hot flashes and vaginal dryness. It’s also used to prevent postmenopausal bone loss. Conjugated estrogens and medroxyprogesterone acetate are the active ingredients in Prempro. The average retail price of 1, 28 tablets of 0.3mg/1.5mg tablet of Prempro is $346.64. To lower the cost of your prescription to $230.64 for 1, 28 tablets of 0.3mg/1.5mg tablet, you can use these Prempro coupons or a SingleCare savings card at participating pharmacies near you.
Prempro FAQs
How much does Prempro cost without insurance?
Without insurance, the average cash price of Prempro is $346.64 for 1, 28 tablets of 0.3mg/1.5mg tablet. Pay as little as $230.64 for 1, 28 tablets of 0.3mg/1.5mg tablet, and save up to 80% on other medications with a free SingleCare savings card.
How much does Prempro cost with insurance?
The copay on your Prempro prescription depends on your health insurance plan and coverage. You will have to check with your pharmacist to determine your cost with insurance. When you use SingleCare's discount card, Prempro costs $230.64 for 1, 28 tablets of 0.3mg/1.5mg tablet. Note: Your cost with our coupons may be cheaper than your cost with insurance.
Does Medicare cover Prempro, and how much does it cost?
Some Medicare prescription plans may cover the cost of your Prempro prescription. Using a SingleCare savings card can get you significant discounts on your Prempro prescriptions. You can also use SingleCare coupons to get instant savings that may be even better than Medicare discounts.
How to save on Prempro
There are many ways to save on a Prempro prescription. You can use a SingleCare coupon, which can bring your cost down to $230.64 for 1, 28 tablets of 0.3mg/1.5mg tablet. Our prescription discount card is usually the quickest and easiest way to save on Prempro and other drugs, and the coupon can be used at over 35,000 pharmacies in the United States. Other ways to save include:
Applying for Medicare Part D Extra Help
Utilizing FSA or HSA funds
Taking advantage of any applicable tax deductions
Seeking manufacturer-sponsored patient assistance programs
Is there a generic of Prempro?
Prempro is a brand-name drug. Conjugated estrogens and medroxyprogesterone acetate are the active ingredients in Prempro. A generic version of Prempro is not yet commercially available. You can use your Prempro coupon card at participating pharmacies to save money on Prempro or Prempro alternatives.
Is there a cheaper alternative to Prempro?
If you are looking to change to an alternative of Prempro, consult your healthcare provider. Only your healthcare provider can determine which drug is best for you. Some examples of Prempro alternatives include:
Where are Prempro coupons from SingleCare accepted?
SingleCare is accepted at most national pharmacies and grocers, including the following:
Learn more about prempro
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