What is Trospium ER: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Trospium ER overview

BRAND NAMES:

  • Sanctura XR

Generic Names:

  • Trospium Chloride Er

Uses:

  • Treats symptoms of an overactive bladder.

Therapeutic Classes:

  • Urinary Antispasmodic

Forms:

  • Long Acting Capsule, Tablet

How it’s taken:

  • By mouth

What is Trospium ER used for?

What form(s) does Trospium ER come in

  • Long Acting Capsule

  • Tablet

What are common Trospium ER doses?

  • Capsule Extended Release 24 Hour 60MG

  • Bottle 30 Capsules Extended Release 24 Hour

Common Trospium ER prescriptions

  • Trospium Chloride ER
    30 capsules extended release 24 hour bottle

  • Trospium Chloride ER
    60mg capsule extended release 24 hour

How to take Trospium ER

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Take this medicine with water on an empty stomach, or at least 1 hour before a meal.

  • Swallow the extended-release capsule whole with water. Do not open, crush, or chew it.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Take this medicine with water on an empty stomach, or at least 1 hour before a meal.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Swallow the extended-release capsule whole with water. Do not open, crush, or chew it.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

What to do if you miss a dose of Trospium ER

  • Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Oral routeAsk your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Trospium ER contraindications

  • Do not use this medicine if you have had an allergic reaction to trospium, or if you have problems passing urine (urinary retention), narrow-angle glaucoma that is poorly controlled, or problems with food emptying from your stomach (gastric retention).

Trospium ER warnings

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, bladder obstruction, myasthenia gravis (severe muscle weakness), narrow-angle glaucoma, ulcerative colitis, or stomach or bowel problems (such as chronic constipation).

  • This medicine may make you sweat less, causing your body temperature to increase. Use extra care not to become overheated during exercise or hot weather, because overheating may result in heatstroke.

  • This medicine may cause you to be dizzy, drowsy, confused, or have blurred vision. Do not drive, use machines, or do anything else that could be dangerous until you know how this medicine affects you.

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

Trospium ER interactions

  • Make sure your doctor knows if you are also using any other medicines to treat incontinence, or other medicines that can cause dry mouth or constipation (such as atropine, dicyclomine, glycopyrrolate, scopolamine, Bentyl®, Robinul®, Transderm Scop®). Tell your doctor if you are also using metformin (Glucophage®), morphine, pancuronium (Pavulon®), procainamide (Procan®, Procanbid®, Pronestyl®), tenofovir (Viread®), or vancomycin (Vancocin®, Vancoled®).

  • Do not drink alcohol within 2 hours of taking this medicine. You may feel very drowsy if you drink alcohol while you use this medicine.

  • This medicine may cause you to be dizzy, drowsy, confused, or have blurred vision. Do not drive, use machines, or do anything else that could be dangerous until you know how this medicine affects you.

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

Trospium ER side effects

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Blistering, peeling, red skin rash

  • Change in how much or how often you urinate, painful or difficult urination, bloody or cloudy urine

  • Fever, chills, cough, sore throat, and body aches

  • Headache

Less Serious Side Effects

  • Constipation, stomach pain, upset stomach, gas, bloating

  • Headache

  • Dry mouth

  • Blurred vision or dry eyes

  • Dizziness, confusion, unusual drowsiness, seeing or hearing things that are not there

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