Orphenadrine ER is a generic prescription skeletal muscle relaxant that helps relieve acute musculoskeletal pain. Doses are taken as extended-release tablets. Without insurance, Orphenadrine ER costs $51.36 per 20, 100mg tablets. A free coupon from SingleCare can get the Orphenadrine ER price to as low as $14.99 for 20, 100mg tablets.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 12/05/2025
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Orphenadrine ER is a generic prescription skeletal muscle relaxant that helps relieve acute musculoskeletal pain. Doses are taken as extended-release tablets. Without insurance, Orphenadrine ER costs $51.36 per 20, 100mg tablets. A free coupon from SingleCare can get the Orphenadrine ER price to as low as $14.99 for 20, 100mg tablets.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Orphenadrine Citrate Er Retail Price | Orphenadrine Citrate Er SingleCare Price |
|---|---|---|
| CVS Pharmacy | $39.20 | $39.00 |
| Walmart | $32.80 | $32.80 |
| Walgreens | $44.00 | $19.40 |
| Kroger Pharmacy | $21.40 | $18.20 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Orphenadrine ER is a generic prescription skeletal muscle relaxant that helps relieve acute musculoskeletal pain. Doses are taken as extended-release tablets. Without insurance, Orphenadrine ER costs $51.36 per 20, 100mg tablets. A free coupon from SingleCare can get the Orphenadrine ER price to as low as $14.99 for 20, 100mg tablets.
The generic version of Orphenadrine ER costs $14.99 for 20, 100mg tablets with a free Orphenadrine ER coupon from SingleCare. You could reduce this cost more depending on your Rx details. Use the dropdown menu above to update your Rx info (i.e., brand/generic, form, dosage, quantity) to see the most accurate prices of Orphenadrine ER with SingleCare at your local pharmacies.
The average retail price of Orphenadrine ER is $51.36 per 20, 100mg tablets. Our lowest cash price for Orphenadrine ER is $14.99 for 20, 100mg tablets.
Health insurance coverage of Orphenadrine ER varies by insurance plan. Some insurance companies do not cover Orphenadrine ER, so it is recommended to check with an insurance representative. Orphenadrine ER is typically placed in lower copay tiers; however, the out-of-pocket cost may vary depending on other associated fees. If Orphenadrine ER is not covered or the out-of-pocket cost is higher than usual, use a SingleCare {drug}} coupon without insurance and pay as little as $14.99 for 20, 100mg tablets.
Medicare Part D and Medicare Advantage drug plans typically do not cover Orphenadrine ER because it is considered a high-risk drug for people older than the age of 65. Medicare patients can use a SingleCare prescription discount card as an alternative. SingleCare’s lowest price for Orphenadrine ER is $14.99 for 20, 100mg tablets.
Medicaid coverage for Orphenadrine ER varies by state. When it is covered, some states consider it a non-preferred drug or one requiring prior authorization. In either case, the prescription may be denied if prior authorization requirements are not met. Medicaid patients who are denied coverage can use a SingleCare savings card as an alternative to Medicaid. The lowest SingleCare price for Orphenadrine ER is $14.99 for 20, 100mg tablets.
There is no brand-name version of Orphenadrine ER.
As a generic drug, Orphenadrine ER offers few opportunities to save money. The first place to start is with SingleCare’s prescription drug discount program. With a SingleCare Orphenadrine ER discount coupon, the Orphenadrine ER price can be as low as $14.99 for 20, 100mg tablets at participating pharmacies. When used regularly, free coupons from SingleCare can earn bonus savings on other prescription medications for people who join SingleCare’s loyalty program.
Patients who meet the income requirements could enroll in Medicaid, Medicare Extra Help, or a 340B provider and purchase Orphenadrine ER at a government-subsidized drug price. They can also explore getting help from nonprofit patient assistance programs.
Healthcare professionals have several pharmaceutical options for treating muscle pain and muscle spasms. Generic Orphenadrine ER and generic methocarbamol are the cheapest muscle relaxants they can prescribe. Other commonly-used muscle relaxants include tizanidine and cyclobenzaprine, but they cost more than Orphenadrine ER. All of these alternatives can be purchased at a discount price by using SingleCare drug coupons. Since side effects are a prominent feature of muscle relaxants, consult with the prescribing healthcare professional for medical advice before switching.
You can use SingleCare coupons at most major pharmacies and grocers, including Walgreens, Kroger, Walmart, CVS, Safeway, and more. Just text, email, print, or save your free Orphenadrine ER coupon to your digital wallet and show a pharmacist at the counter.
SingleCare is accepted at most national pharmacies and grocers, including the following:
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved