Orphenadrine ER Coupons & Prices

Orphenadrine ER is a generic prescription skeletal muscle relaxant that helps relieve acute musculoskeletal pain. Doses are taken as extended-release tablets. Without insurance, Orphenadrine ER costs $51.36 per 20, 100mg tablets. A free coupon from SingleCare can get the Orphenadrine ER price to as low as $14.99 for 20, 100mg tablets.

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Orphenadrine ER coupon at Costco Pharmacy
$ 14.99

Show this free card to your pharmacist.

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Orphenadrine ER coupon at Kroger Pharmacy
$18.12
$ 15.12
$3 off with signupwith signup

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Orphenadrine ER coupon at Harris Teeter Pharmacy
$18.12
$ 15.12
$3 off with signupwith signup
Orphenadrine ER coupon at Walmart Neighborhood Market Pharmacy
$21.64
$ 18.64
$3 off with signupwith signup
Orphenadrine ER coupon at Walmart Pharmacy
$21.64
$ 18.64
$3 off with signupwith signup
Orphenadrine ER coupon at Food Lion Pharmacy
$ 18.80
$ 19.85
$26.48
$ 23.48
$3 off with signupwith signup
$35.94
$ 32.94
$3 off with signupwith signup

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 12/05/2025

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About Orphenadrine ER

Orphenadrine ER is a generic prescription skeletal muscle relaxant that helps relieve acute musculoskeletal pain. Doses are taken as extended-release tablets. Without insurance, Orphenadrine ER costs $51.36 per 20, 100mg tablets. A free coupon from SingleCare can get the Orphenadrine ER price to as low as $14.99 for 20, 100mg tablets.

Orphenadrine ER Price History & Information

Price History for Orphenadrine Citrate Er

20 count, tablet extended release 12 hour, 100mg

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 1-Month Prices for Orphenadrine Citrate Er

20 count, tablet extended release 12 hour, 100mg
PharmacyOrphenadrine Citrate Er Retail PriceOrphenadrine Citrate Er SingleCare Price
CVS Pharmacy$39.20$39.00
Walmart$32.80$32.80
Walgreens$44.00$19.40
Kroger Pharmacy$21.40$18.20

These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Orphenadrine ER

Orphenadrine ER is a generic prescription skeletal muscle relaxant that helps relieve acute musculoskeletal pain. Doses are taken as extended-release tablets. Without insurance, Orphenadrine ER costs $51.36 per 20, 100mg tablets. A free coupon from SingleCare can get the Orphenadrine ER price to as low as $14.99 for 20, 100mg tablets.

Orphenadrine ER FAQs

How much is Orphenadrine ER with SingleCare?

The generic version of Orphenadrine ER costs $14.99 for 20, 100mg tablets with a free Orphenadrine ER coupon from SingleCare. You could reduce this cost more depending on your Rx details. Use the dropdown menu above to update your Rx info (i.e., brand/generic, form, dosage, quantity) to see the most accurate prices of Orphenadrine ER with SingleCare at your local pharmacies.

How much does Orphenadrine ER cost without insurance?

The average retail price of Orphenadrine ER is $51.36 per 20, 100mg tablets. Our lowest cash price for Orphenadrine ER is $14.99 for 20, 100mg tablets.

How much does Orphenadrine ER cost with insurance?

Health insurance coverage of Orphenadrine ER varies by insurance plan. Some insurance companies do not cover Orphenadrine ER, so it is recommended to check with an insurance representative. Orphenadrine ER is typically placed in lower copay tiers; however, the out-of-pocket cost may vary depending on other associated fees. If Orphenadrine ER is not covered or the out-of-pocket cost is higher than usual, use a SingleCare {drug}} coupon without insurance and pay as little as $14.99 for 20, 100mg tablets. 

Does Medicare cover Orphenadrine ER?

Medicare Part D and Medicare Advantage drug plans typically do not cover Orphenadrine ER because it is considered a high-risk drug for people older than the age of 65. Medicare patients can use a SingleCare prescription discount card as an alternative. SingleCare’s lowest price for Orphenadrine ER is $14.99 for 20, 100mg tablets.

Does Medicaid cover Orphenadrine ER?

Medicaid coverage for Orphenadrine ER varies by state. When it is covered, some states consider it a non-preferred drug or one requiring prior authorization. In either case, the prescription may be denied if prior authorization requirements are not met. Medicaid patients who are denied coverage can use a SingleCare savings card as an alternative to Medicaid. The lowest SingleCare price for Orphenadrine ER is $14.99 for 20, 100mg tablets.

What is the brand name for Orphenadrine ER?

There is no brand-name version of Orphenadrine ER.

Ways to save on Orphenadrine ER

As a generic drug, Orphenadrine ER offers few opportunities to save money. The first place to start is with SingleCare’s prescription drug discount program. With a SingleCare Orphenadrine ER discount coupon, the Orphenadrine ER price can be as low as $14.99 for 20, 100mg tablets at participating pharmacies. When used regularly, free coupons from SingleCare can earn bonus savings on other prescription medications for people who join SingleCare’s loyalty program.

Patients who meet the income requirements could enroll in Medicaid, Medicare Extra Help, or a 340B provider and purchase Orphenadrine ER at a government-subsidized drug price. They can also explore getting help from nonprofit patient assistance programs.

Is there a cheaper alternative to Orphenadrine ER?

Healthcare professionals have several pharmaceutical options for treating muscle pain and muscle spasms. Generic Orphenadrine ER and generic methocarbamol are the cheapest muscle relaxants they can prescribe. Other commonly-used muscle relaxants include tizanidine and cyclobenzaprine, but they cost more than Orphenadrine ER. All of these alternatives can be purchased at a discount price by using SingleCare drug coupons. Since side effects are a prominent feature of muscle relaxants, consult with the prescribing healthcare professional for medical advice before switching.

How to use SingleCare for Orphenadrine ER

You can use SingleCare coupons at most major pharmacies and grocers, including Walgreens, Kroger, Walmart, CVS, Safeway, and more. Just text, email, print, or save your free Orphenadrine ER coupon to your digital wallet and show a pharmacist at the counter.

Where are Orphenadrine ER coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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