Zestoretic Coupons & Prices

Zestoretic (lisinopril and hydrochlorothiazide) is a “combination” blood pressure drug that both relaxes blood vessels (ACE inhibitor) and reduces water in the body (diuretic) to reduce blood pressure. Zestoretic is prescribed to patients with high blood pressure who have not succeeded with a single type of drug. The pharmacy price of Zestoretic is $483.35 for 30, 20-12.5mg tablets, but with SingleCare's Zestoretic coupon, it costs $2.88 for 30, 20-12.5mg tablets of generic Zestoretic.

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Zestoretic coupon at Kroger Pharmacy
$5.88
$ 2.88
$3 off with signupwith signup

Show this free card to your pharmacist.

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Zestoretic coupon at Harris Teeter Pharmacy
$5.88
$ 2.88
$3 off with signupwith signup

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Zestoretic coupon at Walmart Neighborhood Market Pharmacy
$5.90
$ 2.90
$3 off with signupwith signup
Zestoretic coupon at Walmart Pharmacy
$5.90
$ 2.90
$3 off with signupwith signup
Zestoretic coupon at Food Lion Pharmacy
$ 13.48
Zestoretic coupon at Walgreens Pharmacy
$17.76
$ 14.76
$3 off with signupwith signup
$18.66
$ 15.66
$3 off with signupwith signup
$18.90
$ 15.90
$3 off with signupwith signup

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 12/05/2025

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About Zestoretic

Zestoretic (lisinopril and hydrochlorothiazide) is a “combination” blood pressure drug that both relaxes blood vessels (ACE inhibitor) and reduces water in the body (diuretic) to reduce blood pressure. Zestoretic is prescribed to patients with high blood pressure who have not succeeded with a single type of drug. The pharmacy price of Zestoretic is $483.35 for 30, 20-12.5mg tablets, but with SingleCare's Zestoretic coupon, it costs $2.88 for 30, 20-12.5mg tablets of generic Zestoretic.

Zestoretic Price History & Information

Price History for Zestoretic (Brand) & Lisinopril-Hydrochlorothiazide (Generic)

30 count, tablet, 20-12.5mg

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 1-Month Prices for Zestoretic (Brand) & Lisinopril-Hydrochlorothiazide (Generic)

30 count, tablet, 20-12.5mg
PharmacyLisinopril-Hydrochlorothiazide Retail PriceLisinopril-Hydrochlorothiazide SingleCare Price
CVS Pharmacy$17.70$17.40
Walmart$7.20$6.00
Walgreens$20.98$11.40
Kroger Pharmacy$16.78$3.29
Albertsons Pharmacy$28.31$5.10

These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Zestoretic

Zestoretic (lisinopril and hydrochlorothiazide) is a “combination” blood pressure drug that both relaxes blood vessels (ACE inhibitor) and reduces water in the body (diuretic) to reduce blood pressure. Zestoretic is prescribed to patients with high blood pressure who have not succeeded with a single type of drug. The pharmacy price of Zestoretic is $483.35 for 30, 20-12.5mg tablets, but with SingleCare's Zestoretic coupon, it costs $2.88 for 30, 20-12.5mg tablets of generic Zestoretic.

Zestoretic FAQs

How much does Zestoretic cost without insurance?

Without insurance, customers can expect to pay $483.35 for 30, 20-12.5mg tablets for Zestoretic, but this price may vary. With a SingleCare savings card, the cost of Zestoretic drops to $2.88 for 30, 20-12.5mg tablets of generic Zestoretic.

How much does Zestoretic cost with insurance?

The amount of your Zestoretic copay depends on your insurance plan. With a SingleCare Zestoretic coupon, your prescription will cost $2.88 for 30, 20-12.5mg tablets of generic Zestoretic, which may be lower than your insurance copay. Consult with your pharmacist to determine what's best for you.

Does Medicare cover Zestoretic and how much does it cost?

Zestoretic is often not covered by Medicare Part D and Medicare Advantage prescription drug plans. Lisinopril and hydrochlorothiazide generic combination drugs, however, usually are covered. For Medicare patients with a prescription for Zestoretic, a SingleCare Zestoretic coupon lowers the cost to $2.88 for 30, 20-12.5mg tablets of generic Zestoretic.

Is there a generic of Zestoretic?

Zestoretic is a brand-name blood pressure medication. At the present time, several different pharmaceutical companies manufacture generic Zestoretic, including Med Pharma, Aurobindo, Hikma, Lupin, Mylan, and several others, as generic lisinopril and hydrochlorothiazide. Before you pay for your Zestoretic prescription, find free coupons for the generic or brand-name Zestoretic on our website or app.

What is Zestoretic?

Zestoretic (lisinopril and hydrochlorothiazide) is a combination blood pressure drug that relaxes the blood vessels and rids the body of extra water. Combined, these effects reduce blood pressure. Zestoretic is prescribed to patients with high blood pressure who have not succeeded with a single type of drug.

Lisinopril belongs to a class of blood pressure medications called ACE inhibitors, which lower blood pressure by blocking the action of a protein (angiotensin) that causes muscles in the blood vessels to contract and tighten the blood vessels. Lisinopril causes the blood vessels to lose tension, so they get wider, and blood pressure goes down.

Hydrochlorothiazide belongs to a class of drugs called diuretics (also called “water pills”) that increase the amount of salt and water in your urine. Lowering the amount of water in the bloodstream lowers the pressure within the blood vessels.

Zestoretic is taken as a tablet once daily.

What are the side effects of Zestoretic?

While medicines may have side effects, many people experience no side effects, or the side effects they experience are very minimal. The most common physical side effects of Zestoretic include lightheadedness, dizziness, headache, fatigue, drowsiness, stomach upset, and blurred vision. Because Zestoretic contains a diuretic, Zestoretic may cause dehydration.

Zestoretic is toxic to fetuses, so it should not be taken by pregnant women.

Allergic reactions are rare and include swelling, rash, and shortness of breath.

This is not a complete list of side effects that may occur. Consult with your doctor or pharmacist about possible side effects before taking this medicine.

Where are Zestoretic coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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