Zosyn overview
BRAND NAMES:
Piperacillin Sodium-Tazobactam Sodium Novaplus, PremierPro Rx Piperacillin and Tazobactam, Zosyn, Zosyn
Generic Names:
Zosyn
Uses:
Treats infections. The medicine contains a penicillin antibiotic.
Therapeutic Classes:
Antibiotic
Forms:
Injectable
How it’s taken:
By injection
What is Zosyn used for?
Zosyn is a prescription only medication that is used to treat bacterial injections such as urinary tract infections and pneumonia. Zosyn works by destroying harmful bacteria in the body. This medication is available as an Intravenous powder for injection and as an Intravenous solution.
What form(s) does Zosyn come in
Injectable
What are common Zosyn doses?
Plas Cont 50ML of 3-0.375GM/50ML
Plas Cont 50ML of 2-0.25GM/50ML
Plas Cont 100ML of 4-0.5GM/100ML
Common Zosyn prescriptions
Zosyn
50ml of 2-0.25gm/50ml bottleZosyn
50ml of 3-0.375gm/50ml bottleZosyn
3.375 (3-0.375)gm solution reconstitutedZosyn
4.5 (4-0.5)gm solution reconstituted
How to take Zosyn
Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein. The medicine must be injected slowly, so your IV tube will need to stay in place for at least 30 minutes.
Injection routeA nurse or other health provider will give you this medicine.
Injection routeA nurse or other health provider will give you this medicine.
Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein. The medicine must be injected slowly, so your IV tube will need to stay in place for at least 30 minutes.
What to do if you miss a dose of Zosyn
Zosyn contraindications
This medicine is not right for everyone. You should not receive it if you had an allergic reaction to piperacillin, tazobactam, or similar antibiotic medicines.
Zosyn warnings
Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, congestive heart failure, cystic fibrosis, or seizures. Tell your doctor if you have a history of allergies or are on a low-salt diet.
This medicine may cause the following problems:Serious skin reactionsBleeding problemsNerve problems, including seizuresKidney problemSevere diarrhea
This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine. It may occur 2 months or more after you stop using this medicine.
Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
Call your doctor if your symptoms do not improve or if they get worse.
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Zosyn interactions
Call your doctor if your symptoms do not improve or if they get worse.
Some foods and medicines can affect how piperacillin/tazobactam works. Tell your doctor if you are using any of the following:Methotrexate, probenecidBlood thinner (including heparin, warfarin)Diuretic (water pill)Other medicine to treat an infection (including tobramycin, vancomycin)
This medicine may cause the following problems:Bleeding problemsSerious skin reactionsSevere diarrhea
This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine. It may occur 2 months or more after you stop using this medicine.
Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Zosyn side effects
Serious Side Effects
Pain, itching, burning, swelling, or a lump under your skin where the needle is placed
Unusual bleeding, bruising, or weakness
Seizures
Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Blistering, peeling, or red skin rash
Bloody or watery diarrhea, stomach cramps, fever
Change in how much or how often you urinate, painful or difficult urination, lower back or side pain
Less Serious Side Effects
Pain, itching, burning, swelling, or a lump under your skin where the needle is placed
Headache, trouble sleeping
Mild diarrhea, constipation, nausea
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