What is Zylet: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Jan 25, 2023

Zylet overview

BRAND NAMES:

  • Zylet, Vasocidin, TobraDex ST, Blephamide S.O.P., Maxitrol, Blephamide, Neo-Polycin HC, Pred-G, Tobradex, Pred-G S.O.P.

Generic Names:

  • Zylet

Uses:

  • Treats inflammation and infection of the eyes. This medicine is combination of a corticosteroid and an antibiotic., Treats infections of the eye and eye irritation, swelling, and redness.

Therapeutic Classes:

  • Aminoglycoside/Corticosteroid Combination, Tetracycline/Corticosteroid Combination, Sulfonamide/Corticosteroid Combination, Chloramphenicol/Corticosteroid Combination

Forms:

  • Liquid, Drop, Ointment

How it’s taken:

  • Into the eye

What is Zylet used for?

What form(s) does Zylet come in

  • Liquid

  • Drop

  • Ointment

What are common Zylet doses?

  • Bottle 5ml of 0.5-0.3%

  • Bottle 10ml of 0.5-0.3%

Common Zylet prescriptions

  • Zylet
    10ml of 0.5-0.3% bottle

  • Zylet
    5ml of 0.5-0.3% bottle

How to take Zylet

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Ophthalmic routeWash your hands with soap and water before and after using this medicine.

  • Ophthalmic routeShake the eye drops well just before each use.

  • Ophthalmic routeTo use the eye drops: Hold the dropper close to your eye with the other hand. Drop the correct number of drops into the pocket made between your lower lid and eyeball. Gently close your eyes. Place your index finger over the inner corner of your eye for 1 minute. Do not rinse or wipe the dropper or allow it to touch anything, including your eye. Put the cap on the bottle right away. Keep the bottle upright when you are not using it.

  • Do not wear contact lenses while using this medicine.

  • Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to. This medicine is not for long-term use.

  • Wash your hands before and after using the medicine.

  • Lie down or tilt your head back. With your index finger, pull down the lower lid of your eye to form a pocket.

  • Shake the eye drops well just before each use.

  • To use the eye drops: Hold the dropper close to your eye with the other hand. Drop the correct number of drops into the pocket made between your lower lid and eyeball. Gently close your eyes. Place your index finger over the inner corner of your eye for 1 minute. Do not rinse or wipe the dropper or allow it to touch anything, including your eye. Put the cap on the bottle right away. Keep the bottle upright when you are not using it.

  • To use the ointment: Hold the tip of the tube close to your eye with the other hand. Avoid touching the tip of the tube to your eye or finger. Squeeze a ribbon of ointment into the pocket between your lower lid and eyeball. Close your eyes for 1 to 2 minutes. Wipe the tip with a clean tissue and close the tube tightly. Keep the tube tightly closed when you are not using it.

  • Take all of the medicine in your prescription to clear up your infection, even if you feel better after the first few doses.

What to do if you miss a dose of Zylet

  • Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Place the container upright.

  • Do not freeze the medicine.

  • Ophthalmic routeAsk your pharmacist, doctor, or health caregiver about the best way to dispose of the used medicine container and any leftover medicine after you have finished your treatment. You will also need to throw away old medicine after the expiration date has passed.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Do not use extra medicine to make up for a missed dose.

  • If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose.

Zylet contraindications

  • You should not use this medicine if you have any bacterial infection, fungal disease, or viral disease in your eye or if you have had an allergic reaction to loteprednol, tobramycin, or any other corticosteroid. You should not use this medicine unless until your doctor tells you to.

  • You should not use this medicine if you are allergic to any antibacterial medicines or to steroids, such as cortisone, hydrocortisone, or prednisone.

Zylet warnings

  • Make sure your doctor knows if you are pregnant or breast feeding.

  • Make sure your doctor knows if you have glaucoma or any other eye disease.

  • Tell your doctor if you have undergone cataract surgery.

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

  • Call your doctor if your symptoms do not improve or if they get worse.

  • Ophthalmic routeIf you hurt your eye, develop an eye infection, or need to have eye surgery, talk with your doctor right away. You may need to change your medicine or stop using it.

  • Sensitivity to light.

  • Severe headache.

  • Make sure your doctor knows if you have glaucoma, cataracts, or any other eye condition before taking this medicine.

  • If you are pregnant or breastfeeding, talk to your doctor before using this medicine.

  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.

Zylet interactions

  • Make sure your doctor knows if you are pregnant or breast feeding.

  • Make sure your doctor knows if you have glaucoma or any other eye disease.

  • Tell your doctor if you have undergone cataract surgery.

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

  • Call your doctor if your symptoms do not improve or if they get worse.

  • Ophthalmic routeIf you hurt your eye, develop an eye infection, or need to have eye surgery, talk with your doctor right away. You may need to change your medicine or stop using it.

  • Make sure your doctor knows if you have glaucoma, cataracts, or any other eye condition before taking this medicine.

  • If you are pregnant or breastfeeding, talk to your doctor before using this medicine.

  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.

Zylet side effects

Serious Side Effects

  • Severe headache.

  • Opacity, or white patches in your eyes.

  • Redness, itching, or pain in your eyes.

  • Dry eyes or irritation in your eyes.

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Blurred vision.

  • High fever.

  • Sensitivity to light.

  • Severe eye irritation that was not there before using this medicine

  • Vision changes

Less Serious Side Effects

  • Stinging of your eyes.

  • Watering of your eyes.

  • Stinging, redness, or burning of the eye

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