Does amoxicillin treat chlamydia?

Medically reviewed by Ashley Wong, Pharm. D.
Licensed Pharmacist
Updated Jan 27, 2026
Datos Verificados

Amoxicillin can treat chlamydia in certain situations, but it is not the preferred treatment. The CDC recommends doxycycline for most people, but amoxicillin is an alternative option for pregnant women when first-line antibiotics aren’t appropriate.

Key takeaways

  • The CDC recommends doxycycline as first-line treatment for chlamydia.

  • Amoxicillin is an alternative treatment for chlamydia during pregnancy.

  • A 2001 study found higher persistent infection rates with amoxicillin (20%) compared with azithromycin (5%) in pregnant patients.

Chlamydia treatment comparison
Treatment CDC first-line? Typical use case
Doxycycline Yes Most adults and adolescents
Azithromycin Alternative Pregnancy (preferred)
Amoxicillin No (alternative) Pregnancy when azithromycin isn’t suitable

Want to learn more about STD treatment? Read our full analysis of amoxicillin for STDs

See more sexual health resources below:

Prescription resources

Amoxicillin is a penicillin antibiotic sometimes used as an alternative treatment for chlamydia during pregnancy. If you’re prescribed amoxicillin and managing treatment costs, you can use SingleCare to compare amoxicillin prices and find coupons at pharmacies near you.

Medical disclaimer: This content is for general informational purposes only and does not constitute medical advice. Always consult your gynecologist or healthcare provider before making changes to your medication regimen.

Sources

Medically reviewed by Ashley Wong, Pharm. D.
Licensed Pharmacist

Ashley Wong, Pharm.D., has worked for healthcare companies where she translated complex drug information into easy-to-understand language for patients. She also served as a Senior Medical Information Specialist at a medical communications company, where she delivered clinically accurate drug information to healthcare providers and patients and compiled adverse event reports in accordance with the FDA's reporting guidelines.

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