Is Prozac safe during pregnancy?

Medically reviewed by Laura K. Grubb, MD, MPH

Board-Certified Pediatrician and Adolescent Medicine Specialist

Contributing writer

Updated Feb 4, 2026 • Published Jan 12, 2026

Fact Checked

Prozac is considered by many healthcare professionals to be generally safe during pregnancy. Research shows only a small increased risk of certain birth defects, while untreated depression poses significant risks to both mother and baby, so experts emphasize weighing the benefits of treatment against potential risks with a healthcare provider.

Interested in learning more about Prozac (fluoxetine) use during pregnancy? Read our full analysis: Is it safe to take Prozac (fluoxetine) during pregnancy?

Medical disclaimer: This content is for general informational purposes only and does not constitute medical advice. Always consult your OB-GYN or other healthcare provider before making changes to your medication regimen.

Medically reviewed by Laura K. Grubb, MD, MPH

Board-Certified Pediatrician and Adolescent Medicine Specialist

Laura K. Grubb, MD, MPH, is a board-certified pediatrician and adolescent medicine specialist. She cares for patients in an urban academic medical center and is active with national organizations focusing on child health, public health, and adolescent health care. In addition, she has been a volunteer with the Amigos de Las Americas organization since 1990—first as a community volunteer and now as a medical advisor.

Written by Sara Lindberg

Contributing writer

Sara Lindberg is a freelance writer focusing on health, wellness, and fitness. She holds a bachelor's degree in exercise science and a master's degree in counseling. Her work has been featured in Healthline, Verywell, LIVESTRONG, Headspace, INSIDER, MindBodyGreen, Men's Health, Runner's World, Bicycling Magazine, SheKnows, and Active.com, among others.

Is Prozac safe during pregnancy?

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