Is Vyvanse the same as Adderall?
No, Vyvanse is not the same as Adderall, though both are stimulant medications used to treat ADHD. Adderall contains mixed amphetamine salts and comes in immediate- and extended-release forms, while Vyvanse contains lisdexamfetamine, which may lower abuse risk and lasts longer.
Key takeaways
Vyvanse contains lisdexamfetamine, a prodrug that becomes active only after conversion in the GI tract and liver, while Adderall contains mixed amphetamine salts.
Vyvanse is taken once daily and can last up to 14 hours, whereas Adderall IR lasts 4-6 hours and Adderall XR lasts 8-12 hours.
Both medications are Schedule II controlled substances and require monitoring for side effects, interactions, and misuse risk.
Compare Adderall vs. Vyvanse |
||
|---|---|---|
| Features | Adderall | Vyvanse |
| Active ingredient | Dextroamphetamine/amphetamine | Lisdexamfetamine |
| Drug type | CNS stimulant | CNS stimulant |
| Release mechanism | Immediate or extended release | Prodrug (activated in body) |
| Typical duration | 4-6 hours (IR), 8-12 hours (XR) | Up to 14 hours |
| Conditions treated | ADHD, narcolepsy | ADHD, binge eating disorder (adults) |
| Abuse potential | Higher | Potentially lower |
| Cost without insurance | $125 for 60, 20 mg tablets of generic Adderall | $437 for 30, 30 mg capsules of generic Vyvanse |
Expert perspective
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Blair Gingerich, Pharm.D.
“I have seen people do very well with Adderall and horribly with Vyvanse. I’ve also seen people struggle, trying a few options until they start Vyvanse. This is where medicine can be more of an art than a science.”
Expert bio: Blair Gingerich is an ambulatory care pharmacist in Northern Indiana.
Want a deeper look? Read our full comparison of Vyvanse vs. Adderall
See more Vyvanse vs. Adderall comparisons below:
Prescription resources
Adderall and Vyvanse are Schedule II controlled substances that require a valid prescription. If you are prescribed either medication and navigating insurance coverage or rising costs, SingleCare can help you compare pharmacy prices and find available coupons for both Adderall and Vyvanse.
Medical disclaimer: This content is for general informational purposes only and does not constitute medical advice. Always consult your psychiatrist or other healthcare provider before making changes to your medication regimen.
Sources
Adderall, National Library of Medicine DailyMed
Vyvanse, National Library of Medicine DailyMed
Drug scheduling, United States Drug Enforcement Administration
Blair Gingerich, Pharm.D., an ambulatory care pharmacist in Northern Indiana
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