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Postnasal Drip Treatments and Medications

Medically reviewed by Gerardo SisonPharm.D.
Licensed Pharmacist
Updated Aug 5, 2026
Fact Checked

Key takeaways

  • The treatment for postnasal drip depends on the cause, although a steroid nasal spray like fluticasone is a common option if allergies are the trigger.

  • Over-the-counter medicine for postnasal drip includes steroid nasal sprays, antihistamines, decongestants, and expectorants.

  • Natural remedies for postnasal drip include saline nasal rinses, using a humidifier, sleeping with a slightly elevated head, and sipping warm liquids with honey.

Postnasal drip refers to the sensation of mucus traveling from the back of the nose to the throat, which can lead to symptoms like an irritated or sore throat, coughing, and a hoarse voice. For many people, allergies and respiratory infections like the common cold are common cause of postnasal drip. While most cases of postnasal drip improve on their own within a couple of weeks, certain medications may help improve symptoms. For example, a steroid nasal spray, in addition to a saline rinse, can help reduce inflammation from allergies in the nasal passages. In any case, it’s best to see a healthcare provider if symptoms worsen or continue for more than 10 days.

RELATED: What does the color of your snot say about your health? 

How is postnasal drip diagnosed? 

Postnasal drip is typically a symptom of an underlying condition. A healthcare provider can directly examine the nose and throat and review a person’s medical history to determine the best treatment option. An evaluation may include:

  • Questions about what’s causing the symptoms, any medications being taken, and whether the cough worsens at night

  • Allergy testing to see whether specific allergens, like dust mites or pollen, are causing symptoms

  • Nasal endoscopy, which involves using a thin camera to see into the nasal passages

  • Imaging tests, such as a CT scan, especially if a sinus problem or deviated septum is potentially causing symptoms

After determining the cause of postnasal drip, a healthcare provider can recommend treatment. In some cases, postnasal drip is a sign of a more serious condition that may require medical care, especially if accompanied by a high fever or trouble breathing. 

Postnasal drip treatment options

Treating postnasal drip means treating whatever is causing the mucus. Options for managing postnasal drip usually start with home remedies and medications to reduce inflammation and clear mucus. If a bacterial infection is causing symptoms, then an antibiotic may be prescribed. In severe cases like a deviated septum, surgery may be recommended.

Postnasal drip medications 

Various medications can help manage postnasal drip. Most medications for postnasal drip are available over the counter, including steroid nasal sprays, antihistamines, decongestants, and expectorants.

Steroid Sprays

Steroid nasal sprays can help reduce inflammation that may be causing excess mucus. They’re often a first-line treatment for allergic rhinitis, which can cause symptoms such as nasal congestion and postnasal drip. Options include Flonase (fluticasone), Nasacort Allergy 24HR (triamcinolone), and Nasonex (mometasone), which are all available without a prescription. It could take a few days to see relief and several weeks to experience their maximum effects.

Oral antihistamines 

Antihistamines are the most common treatment options for allergies. Second-generation antihistamines like Claritin (loratadine), Zyrtec (cetirizine), Allegra (fexofenadine), and Xyzal (levocetirizine) can help if symptoms are caused by exposure to dust mites, pollen, or other allergens. In some cases, a first-generation antihistamine like Benadryl (diphenhydramine) or Chlor-Trimeton (chlorpheniramine) may be recommended, as they have drying effects that can help reduce postnasal drip. However, first-generation antihistamines often cause more drowsiness than newer second-generation ones and should be avoided in older adults.

Antihistamine nasal sprays

Antihistamines are also available as nasal sprays that can work directly in the nasal passages. Astepro (azelastine) is an option for adults and children 6 and older. It may be used alongside a steroid spray, especially if symptoms are not improving with just one medicine. 

Decongestants

Decongestants work by shrinking the blood vessels in the nasal passages, which may help reduce mucus drainage. Sudafed (pseudoephedrine) is the most common decongestant used to treat postnasal drip and stuffiness from an upper respiratory tract infection. Afrin (oxymetazoline) is a decongestant nasal spray that can work quickly, but it should not be used for more than a few days in a row due to the risk of rebound congestion

Expectorants

Expectorants may also help manage postnasal drip. They work by thinning the mucus to make it easier to clear. Mucinex, which contains guaifenesin, is a common expectorant, although study results are mixed regarding the meaningfulness of its benefits. 

Prescription medications

A prescription nasal spray, such as ipratropium bromide, can help treat a runny nose that may be causing postnasal drip. Singulair (montelukast) is another prescription option available as an oral tablet and approved for allergic rhinitis. These medications are not first-line options and may be prescribed for more serious cases after a visit to a healthcare provider.

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What is the best medication for postnasal drip?

Drug nameSee SingleCare price
Flonase Sensimist
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Flonase Allergy Relief
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Nasacort Allergy 24hr
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Nasonex
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Astepro
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Dymista
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Claritin
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Zyrtec
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Allegra Allergy
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Xyzal Allergy 24hr
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Pseudoephedrine
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Afrin Original
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Mucinex
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Ipratropium
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This is not an exhaustive list of postnasal drip medications. Always ask your healthcare provider for the best treatment for postnasal drip based on your health condition and medical history.

Common side effects of postnasal drip medicine

Side effects will vary based on the medication used:

  • Steroid nasal sprays: irritation, sneezing, headaches, and nosebleeds

  • Antihistamines: drowsiness, dry mouth, dizziness, and blurred vision, although these side effects are more serious with older antihistamines

  • Decongestants: trouble sleeping, increased blood pressure, and nervousness, with a potential risk of rebound congestion with nasal decongestants

  • Expectorants: nausea, dizziness, and headache

This is not a complete list of side effects. Consult a healthcare provider for other adverse effects, and seek immediate care for signs of an allergic reaction, such as hives, trouble breathing, or swelling of the face or throat. 

Home remedies for postnasal drip 

Home remedies won’t cure an underlying allergy or infection. However, they can help with easing postnasal drip and other symptoms that may occur, such as coughing and a sore throat. 

  • Try a nasal saline rinse: A nasal saline rinse, also known as nasal irrigation, with a neti pot or simple squeeze bottle, can help clear out mucus and allergens. It’s important to use distilled or sterile water and to clean and dry the device after each use.

  • Use steam or a humidifier: For many people with postnasal drip, dry air may be contributing to postnasal drip. Taking a hot shower with steam or using a humidifier can help thin the mucus.

  • Sip warm tea with honey: Honey can help with a sore throat, cough, and other symptoms linked to postnasal drip. Add a small amount to warm tea to help soothe the throat. Avoid giving honey to children under 1 year old.

  • Elevate your head while sleeping: Lying down flat can cause mucus to pool in the back of the throat and worsen postnasal drip. Use a couple of pillows to keep the head propped up and allow the mucus to drain. 

  • Stay hydrated throughout the day: Drinking enough fluids can help keep mucus from thickening. Warm liquids like broth and tea can also help relieve throat irritation. 

Home remedies can be comforting, but they’re not replacements for medical care. It’s important to see a healthcare provider if symptoms don’t improve after around 10 days, or if a bacterial infection is suspected.

Expert takeaway 

Many people opt for an oral antihistamine if allergies are causing postnasal drip. However, a steroid nasal spray is often more effective, though it may take a week or two to see a difference. 

Frequently asked questions about postnasal drip 

How to get rid of postnasal drip 

A saline rinse is one of the quickest ways to relieve postnasal drip, as it helps clear mucus directly. However, a nasal antihistamine spray can also work quickly within 30 minutes if allergies are the culprit. Although steroid sprays are effective for symptoms, they often take longer to show their full benefits.

How long can postnasal drip last? 

Postnasal drip usually lasts for a week or two after a cold or allergy flare. However, if symptoms haven't improved after around 10 days, it’s best to see a healthcare provider. A bacterial sinus infection or chronic condition could be causing long-lasting symptoms.

Is postnasal drip contagious?

Postnasal drip itself is not contagious, but it could be a sign of an underlying infection that could be spread to others. Allergies are among the most common causes of postnasal drip and are not contagious.

How can I stop coughing from postnasal drip at night? 

Nighttime coughing from postnasal drip is usually caused by lying flat. Elevating your head with a couple of pillows can help avoid mucus from pooling in the back of the throat and causing irritation. In addition, home remedies such as a humidifier, saline rinses, and a small amount of honey in tea may be helpful before bedtime.

Can postnasal drip be treated without medication?

Yes, postnasal drip can often be treated without medication. It usually improves as the body clears whatever is causing it. However, postnasal drip caused by allergies usually needs medication to help better control it.

Sources

Medically reviewed by Gerardo SisonPharm.D.
Licensed Pharmacist

Gerardo Sison, Pharm.D., graduated from the University of Florida. He has worked in both community and hospital settings, providing drug information and medication therapy management services. As a medical writer, he hopes to educate and empower patients to better manage their health and navigate their treatment plans.

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