Advair Diskus is a brand-name combination inhaler approved by the FDA to treat and prevent the symptoms of asthma and chronic obstructive pulmonary disease (COPD). Advair Diskus contains a corticosteroid called fluticasone propionate and a long-acting beta-agonist (LABA) called salmeterol. Advair Diskus is available as a generic medication. On average, brand-name Advair Diskus costs $502.07 for 1, 60 dose inhaler, 250-50mcg/act inhaler. You can pay as low as $57.96 for 1, 60 dose inhaler, 250-50mcg/act inhaler of generic Advair Diskus with a SingleCare card.
Edit your dosage
1 inhaler, 60 dose inhaler, 100-50mcg/actEdit
You have 0.00 in available bonus savings. Bonus savings will be automatically applied to your next eligible prescription fill.
Show this free card to your pharmacist.
SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 05/05/2026
Advair Diskus is a brand-name combination inhaler approved by the FDA to treat and prevent the symptoms of asthma and chronic obstructive pulmonary disease (COPD). Advair Diskus contains a corticosteroid called fluticasone propionate and a long-acting beta-agonist (LABA) called salmeterol. Advair Diskus is available as a generic medication. On average, brand-name Advair Diskus costs $502.07 for 1, 60 dose inhaler, 250-50mcg/act inhaler. You can pay as low as $57.96 for 1, 60 dose inhaler, 250-50mcg/act inhaler of generic Advair Diskus with a SingleCare card.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Advair Diskus Retail Price | Fluticasone-Salmeterol Retail Price | Fluticasone-Salmeterol SingleCare Price |
|---|---|---|---|
| CVS Pharmacy | $228.00 | $315.00 | $61.20 |
| Walmart | $345.00 | $117.43 | $83.83 |
| Walgreens | $463.20 | $135.00 | $115.80 |
| Kroger Pharmacy | $247.20 | $444.60 | $105.00 |
| Albertsons Pharmacy | - | $363.00 | $103.20 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Advair Diskus is a brand-name combination inhaler approved by the FDA to treat and prevent the symptoms of asthma and chronic obstructive pulmonary disease (COPD). Advair Diskus contains a corticosteroid called fluticasone propionate and a long-acting beta-agonist (LABA) called salmeterol. Advair Diskus is available as a generic medication. On average, brand-name Advair Diskus costs $502.07 for 1, 60 dose inhaler, 250-50mcg/act inhaler. You can pay as low as $57.96 for 1, 60 dose inhaler, 250-50mcg/act inhaler of generic Advair Diskus with a SingleCare card.
Advair Diskus is a brand-name combination inhaler approved by the FDA. It contains a combination of fluticasone propionate and salmeterol. Advair Diskus is used to control and prevent symptoms of asthma and chronic obstructive pulmonary disease (COPD). The daily use of Advair Diskus can help treat and prevent symptoms, such as shortness of breath and wheezing.
Fluticasone propionate is a corticosteroid that works by reducing inflammation, while salmeterol is a long-acting beta-agonist that works as a bronchodilator to open up the airways and make breathing easier. The combination of these drugs can help manage COPD, which includes chronic bronchitis and emphysema, and asthma.
Patients should note that Advair Diskus is not a rescue inhaler for asthma attacks or acute bronchospasms. Instead, it is a maintenance treatment that is meant to be used daily to control symptoms.
Advair Diskus is available in different strengths. It is typically prescribed to be administered twice daily. Consult your healthcare provider for more information and medical advice before using Advair Diskus.
Advair Diskus is approved for use in adults and children who are at least four years old.
Common side effects of Advair Diskus include headache, throat irritation, nausea, vomiting, cough, hoarseness, upper respiratory tract infection, and bone or muscle pain. Serious side effects may include fungal infections of the mouth (thrush), an increased risk of infections, adrenal function problems, and eye problems. Advair Diskus may cause slowed growth in children. In addition, Advair Diskus may worsen breathing problems in some people.
Seek immediate medical attention if you experience symptoms or signs of an allergic reaction after using Advair Diskus. Symptoms or signs of serious allergic reactions include hives, rash, swelling of the face or throat, and breathing problems.
Contact your healthcare provider immediately if you experience side effects that persist or worsen. Talk to your healthcare provider before using Advair Diskus to find out about other possible side effects, warnings, and precautions.
Fluticasone propionate and salmeterol are processed in the liver by the CYP3A4 enzyme. Drugs that inhibit or block this enzyme could lead to increased blood levels of fluticasone propionate and salmeterol, which could cause increased side effects. CYP3A4 inhibitors include ritonavir, ketoconazole, and clarithromycin.
Advair Diskus should be used with caution in combination with monoamine oxidase inhibitors (MAOIs) or tricyclic antidepressants. Caution should also be used when using Advair Diskus within two weeks of stopping an MAOI or tricyclic antidepressant. Combining these medications could increase the risk of side effects from salmeterol.
Beta-blockers should be avoided or used with caution in people who use Advair Diskus. Beta-blockers can decrease the effects of long-acting beta-agonists, such as salmeterol, on the lungs. Cardioselective beta-blockers may be preferred in people who have asthma or COPD.
Caution should be taken when combining non-potassium-sparing diuretics with Advair Diskus. The use of Advair Diskus may worsen low potassium levels or ECG changes that result from the use of non-potassium-sparing diuretics.
Tell your healthcare provider about any medications you may be taking, including prescription medications, over-the-counter medications, and herbal supplements, before using Advair Diskus.
People with a history of allergic reactions to milk proteins or any of the ingredients in Advair Diskus should avoid using Advair Diskus. In addition, Advair Diskus should be avoided in people experiencing an acute COPD or asthma attack.
Tell your healthcare provider about other medical conditions you have, especially if you have heart disease, high blood pressure, thyroid problems, seizures, diabetes, liver problems, low bone mineral density, immune system problems, eye problems, or an infection. You should also tell your healthcare provider if you are pregnant or breastfeeding before starting treatment.
Wixela Inhub is an FDA-approved generic version of Advair Diskus that may be a cheaper alternative to brand-name Advair Diskus. The generic version is just as effective as the brand-name version, as they contain the same active ingredients.
Other COPD and asthma medications may be available as alternatives to Advair Diskus. Alternatives to Advair Diskus include Dulera (mometasone/formoterol), Breo (fluticasone/vilanterol), and Symbicort (mometasone/formoterol). These inhaler medications contain a combination of an inhaled corticosteroid and long-acting beta-agonist like Advair Diskus. Check with your healthcare provider to see if a cheaper alternative to Advair Diskus is a potential treatment option for you.
Without health insurance, Advair Diskus costs an average retail price of $502.07 for 1, 60 dose inhaler, 250-50mcg/act inhaler. The price can vary depending on the quantity prescribed and the pharmacy location where it is purchased. By using SingleCare, you may be able to save on the cash price of Advair Diskus. With a SingleCare discount card, you may be able to pay as low as $57.96 for 1, 60 dose inhaler, 250-50mcg/act inhaler. Ask your local pharmacy to run your SingleCare savings card to compare Advair Diskus prices.
The price of Advair Diskus with insurance coverage depends on your particular insurance plan. Contact your insurance provider or pharmacist to determine your copay or coinsurance amount for Advair Diskus. If you have not met your deductible, you may be responsible for the full cash price of Advair Diskus. With SingleCare, you could pay $57.96 for 1, 60 dose inhaler, 250-50mcg/act inhaler, which may be lower than the price with insurance. Use a SingleCare discount card to save as much as 80% on your prescription drugs.
Medicare Part D and Medicare Advantage plans may help cover the cost of Advair Diskus. Contact your pharmacist or plan’s provider to determine your prescription costs with Medicare. The cost with Medicare may depend on other factors, such as the quantity prescribed and your coverage stage. If Medicare does not cover Advair Diskus, you may be able to save money on your prescription medicine with SingleCare. SingleCare offers a free prescription discount card that may reduce prescription drug prices. Compare the price with SingleCare to the cost with Medicare coverage to find out how much you could save.
Gerardo Sison, Pharm.D., graduated from the University of Florida. He has worked in both community and hospital settings, providing drug information and medication therapy management services. As a medical writer, he hopes to educate and empower patients to better manage their health and navigate their treatment plans.
...SingleCare is accepted at most national pharmacies and grocers, including the following:
Health education, drug info, wellness & more
SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
© 2026 SingleCare Administrators. All rights reserved
© 2026 SingleCare Administrators. All rights reserved