The first-line treatment for asthma is an inhaled corticosteroid (ICS), with current guidelines recommending an ICS-formoterol combination for quick relief or long-term symptom management.
Over-the-counter asthma medicines are limited, with Primatene Mist as the only approved epinephrine inhaler for mild intermittent asthma.
There are no home remedies that can cure asthma, although avoiding triggers and keeping a healthy lifestyle may help manage flare-ups.
Asthma is a common, lifelong condition that causes inflammation and narrowing in the airways. People with asthma often experience wheezing, shortness of breath, coughing, and chest tightness. These asthma attacks or flare-ups can occur due to different triggers, including smoke, cold air, and even exercise. While it’s not a curable disease, it can be managed with the right medications that help reduce inflammation and open up the airways. It’s important to see a healthcare provider for symptoms that are severe or occur frequently, especially if breathing problems become harder to manage.
Experiencing symptoms such as wheezing and difficulty breathing is usually enough to warrant a visit to a healthcare provider. They may make a diagnosis themselves or refer an individual to a pulmonologist or allergist. A diagnosis could entail the following:
A review of symptoms and potential triggers: A healthcare provider may ask about symptoms, family history, and potential triggers for breathing problems.
A physical exam: This usually includes listening to breathing patterns and checking for possible signs of allergies.
Pulmonary function tests: A spirometer is a device that measures airflow and can be used to check the effects of any narrowing or inflammation in the lungs.
Other tests: A peak flow meter can track breathing at home, while allergy tests can identify triggers. A fractional exhaled nitric oxide (FeNO) test can also measure airway inflammation to aid a diagnosis.
The severity and frequency of symptoms are key in determining what stage and type of asthma a person has. With this information, a healthcare provider can better understand potential treatment options.
Asthma has no specific cure. Instead, treatment options are meant to control symptoms and prevent the condition from worsening. Avoiding potential triggers and using medication are the main options. Maintenance asthma medications are used every day to help manage airway inflammation for long-term control. In contrast, rescue medications are used during a flare-up to help open up the lungs. A healthcare provider may adjust treatment based on symptom control, with biologic injections and certain procedures reserved for severe cases.
Patients with asthma will have an asthma action plan, or management plan. The plan lists the patient’s medications and instructions. It also describes what to do when certain symptoms occur, and when to contact the healthcare provider or seek emergency medical attention. If you or your child does not have an action plan, you can download and print one, then bring it to your healthcare provider to discuss and complete together.
Most asthma medications are inhaled and can work in different ways depending on the drug class. Some people may need to use more than one medication.
Inhaled corticosteroids (ICS) are the first-line controller medication that helps reduce airway inflammation over time. Examples include Pulmicort (budesonide) and QVAR RediHaler (beclomethasone). Short treatment courses of oral steroids like prednisone may be prescribed for severe asthma flare-ups.
Beta agonists are medications that relax the muscles in the airways. Short-acting beta agonists (SABAs) can relieve symptoms during an asthma attack, with common examples including Ventolin HFA (albuterol) and Xopenex (levalbuterol). Long-acting beta agonists (LABAs) are used daily and provide longer-lasting control of symptoms, with examples including Serevent (salmeterol) and formoterol. Beta agonists are mainly used alongside an ICS, never alone.
Combination inhalers have more than one medication to help better control symptoms that don’t improve with just one. The most commonly prescribed combination for asthma is an inhaled steroid with a long-acting bronchodilator. Symbicort (budesonide and formoterol) is an ICS-formoterol combination that can both control and relieve symptoms. Other similar combinations include Advair Diskus (fluticasone and salmeterol), Breo Ellipta (fluticasone furoate and vilanterol), and Dulera (mometasone and formoterol).
LAMAs, such as Spiriva Respimat (tiotropium), are bronchodilators that can be added to a combination inhaler for severe asthma. These medications can help further open the airways and improve breathing. They’re taken daily, not as a rescue inhaler.
Leukotriene modifiers are medications taken by mouth that help block leukotrienes, which are chemicals that can contribute to asthma-related inflammation. Singulair (montelukast) is the most common medication in this drug class, although Accolate (zafirlukast) is another option.
Biologics, or monoclonal antibodies, are injectable medications to control symptoms of severe asthma. They work by blocking or modifying the immune response that can cause airway inflammation. They’re mainly used if other inhalers aren’t enough to manage the disease. Examples include Xolair (omalizumab) and Dupixent (dupilumab).
There are very few over-the-counter options for asthma. Primatene Mist is an over-the-counter epinephrine inhaler, but it is not usually recommended as a substitute for prescription inhalers to manage asthma. Keep in mind that some products could trigger asthma symptoms, including NSAIDs like ibuprofen and aspirin. Consult a healthcare provider if you’re not sure about whether you can take an over-the-counter medicine with asthma.
RELATED: How much do inhalers cost?
| Drug name | See SingleCare price |
|---|---|
| Symbicort | Get free coupon |
| Dulera | Get free coupon |
| Ventolin HFA | Get free coupon |
| Xopenex | Get free coupon |
| Pulmicort | Get free coupon |
| Qvar Redihaler | Get free coupon |
| Advair Diskus | Get free coupon |
| Breo Ellipta | Get free coupon |
| Spiriva Respimat | Get free coupon |
| Singulair | Get free coupon |
This is not an exhaustive list of asthma medications. Always ask your healthcare provider for the best asthma treatment based on your health condition and medical history.
Like other medications, asthma medicines can cause side effects. However, side effects can vary from person to person, with some people experiencing none at all. The side effects will also depend on the drug being taken.
Beta agonists: tremor, fast heartbeat, headache, and nervousness
Inhaled corticosteroids: sore throat, a hoarse voice, and oral thrush
LAMAs: dry mouth, sore throat, and cough
Leukotriene modifiers: headache, upset stomach, and mood or behavior changes
Biologics: injection-site reactions, headache, and, in rare cases, allergic reactions
This is not a complete list. Consult a healthcare provider for other potential side effects, especially before stopping a medication.
Home remedies are not meant to replace asthma medication. However, certain lifestyle changes can help support treatment and reduce flare-ups.
Avoid triggers as much as possible: If you know what causes an asthma attack, limit your exposure to them, especially if triggers include pollen, smoke, or pet dander.
Reduce indoor allergens: Try an air purifier, wash bedsheets regularly, and keep windows closed if pollen or pollution levels are high.
Avoid smoke: Smoke, whether secondhand smoke or from vaping, can irritate the lungs and airways.
Maintain a healthy lifestyle: Exercise, sleep, and diet are all key factors that can support overall health when you have asthma.
In all cases, you’ll want to follow your asthma action plan. This personalized plan can help keep your symptoms at bay if you follow it closely.
If you're using a rescue inhaler more than a couple of times per week, it could be a sign that the dose of your controller inhaler needs to be adjusted. It’s best to see a healthcare provider and avoid waiting until asthma attacks get more severe.
There is no single best medicine for asthma, as treatment depends on the stage and severity of the condition. Most people do well with a daily controller medication and a rescue inhaler. Current guidelines recommend a combination ICS-formoterol inhaler that can help control and relieve symptoms.
Asthma inhalers send medicine directly to the lungs, which usually means fewer systemic side effects than oral drugs. Any potential side effects come from the medication, not the inhaler itself. People with an allergy to milk proteins should ask their healthcare provider about using dry-powder inhalers since they may contain lactose.
RELATED: How to properly administer an inhaler to your child
Asthma can be managed at home by avoiding potential triggers such as dust and smoke and by using an air purifier. Breathing exercises may help support lung muscle function, but they don’t replace the need for medication. Always take asthma medicines as prescribed.
Some natural ways to support your health with asthma include staying active and eating a balanced diet. You’ll also want to avoid smoking, including secondhand smoking and vaping, which could worsen asthma symptoms. If stress is a trigger, relaxation exercises may help.
Asthma, StatPearls (2024)
What is a FeNO test?, American Academy of Allergy, Asthma & Immunology (2023)
Types of asthma, American College of Allergy Asthma and Immunology
2025 GINA strategy report, Global Initiative for Asthma
Asthma action plan, Asthma and Allergy Foundation of America
Biologics for the management of severe asthma, American Academy of Allergy, Asthma & Immunology (2026)
Gerardo Sison, Pharm.D., graduated from the University of Florida. He has worked in both community and hospital settings, providing drug information and medication therapy management services. As a medical writer, he hopes to educate and empower patients to better manage their health and navigate their treatment plans.
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