Afinitor is a brand-name prescription drug used to treat a range of cancers, including advanced breast cancer in postmenopausal women, neuroendocrine tumors, kidney cancer, and tuberous sclerosis, a cancer of the brain, kidneys, eyes, heart, lungs, and skin. The active ingredient in Afinitor, everolimus, works by blocking proteins on the surface of cancer cells that signal the cell to produce more cancer cells. Afinitor costs $24,258.26 for 1, 28 tablets box at full price. A SingleCare Afinitor coupon reduces that price to $429.08 for 28, 5mg tablets of generic Afinitor.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 05/05/2026
Afinitor is a brand-name prescription drug used to treat a range of cancers, including advanced breast cancer in postmenopausal women, neuroendocrine tumors, kidney cancer, and tuberous sclerosis, a cancer of the brain, kidneys, eyes, heart, lungs, and skin. The active ingredient in Afinitor, everolimus, works by blocking proteins on the surface of cancer cells that signal the cell to produce more cancer cells. Afinitor costs $24,258.26 for 1, 28 tablets box at full price. A SingleCare Afinitor coupon reduces that price to $429.08 for 28, 5mg tablets of generic Afinitor.
Afinitor is a brand-name prescription drug used to treat a range of cancers, including advanced breast cancer in postmenopausal women, neuroendocrine tumors, kidney cancer, and tuberous sclerosis, a cancer of the brain, kidneys, eyes, heart, lungs, and skin. The active ingredient in Afinitor, everolimus, works by blocking proteins on the surface of cancer cells that signal the cell to produce more cancer cells. Afinitor costs $24,258.26 for 1, 28 tablets box at full price. A SingleCare Afinitor coupon reduces that price to $429.08 for 28, 5mg tablets of generic Afinitor.
At most pharmacies, the average retail price of Afinitor will be $24,258.26 for 1, 28 tablets box without insurance coverage. That same prescription will cost $429.08 $429.08 for 28, 5mg tablets of generic Afinitor. using a SingleCare savings card, which you can use at participating pharmacies.
Depending on your health insurance plan, the copay cost of Afinitor will vary. With a SingleCare Afinitor coupon, though, Afinitor costs only $429.08 $429.08 for 28, 5mg tablets of generic Afinitor, which may be lower than your copay. It's worth asking your pharmacist to compare that SingleCare cost to your copay for Afinitor, and other prescription drugs, so you get the best price.
Medicare prescription drug insurance plans usually do provide coverage for Afinitor with prior authorization, but generic everolimus usually is not covered. Talk to your Medicare prescription drug case manager for more information about your Afinitor prescription. If you don't have Medicare coverage, consider using a SingleCare Afinitor prescription discount card for your prescription. With SingleCare, the lowest price for Afinitor is $429.08 $429.08 for 28, 5mg tablets of generic Afinitor.
Afinitor is a brand-name prescription drug with the active ingredient everolimus. Generic everolimus is available from Par Pharmaceutical.
Afinitor is a brand-name prescription drug used to treat a variety of cancers, including breast cancer, neuroendocrine tumors, kidney cancer, and tuberous sclerosis.
Afinitor is used in combination with other drugs to treat advanced breast cancer in post-menopausal women. Advanced breast cancer is one that is aggressively growing and likely to spread to the rest of the body.
Neuroendocrine tumors (NET) are cancers that start in hormone-producing cells or nerves in the intestines, stomach, lung, pancreas, and other parts of the body. Afinitor is used to treat inoperable neuroendocrine tumors of the lung, intestines, or pancreas that are advanced (at risk of spreading to the rest of the body) or metastatic (have spread to the rest of the body).
Afinitor is used to treat advanced renal cell carcinoma. Renal cell carcinoma is a cancer of the tiny tubes in the kidney which then spreads to other kidney tissues.
Finally, Afinitor is approved for the treatment of a number of tuberous sclerosis complex (TSC) tumors. Tuberous sclerosis is a rare disorder that causes usually non-cancerous tumors (tubers) in several places around the body: skin, eyes, brain, kidneys, heart, lungs, and so on. TSC is the leading cause of genetic epilepsy; about 85% to 90% of patients with TSC have seizures. Only about 1 in 3 TSC patients respond at all to anti-seizure medications. Afinitor is approved to reduce TSC tumors in the kidneys (renal angiomyolipoma), TSC of the brain (subependymal giant cell astrocytoma, or SEGA), and to help reduce the number of partial seizures in TSC patients.
The active ingredient in Afinitor, abemaciclib, belongs to a class of anti-cancer drugs called kinase inhibitors. Abemaciclib works by blocking proteins on the surface of the cancer cells that, among other things, signal the cancer cell to divide and produce more cells. It's believed that these proteins, kinase receptors, become overactive in cancer cells. Blocking this protein slows or stops the growth of tumors.
Afinitor is administered as a tablet or oral solution (Afinitor Disperz) once daily until sufficient progress has been made against the cancer or the patient can no longer tolerate Afinitor.
Common side effects of Afinitor include diarrhea, nausea, vomiting, constipation, headache, loss of appetite, weight loss, dry skin, pimples, nosebleeds, mouth sores, temporary hair loss, arm pain, leg and joint pain, altered taste, and swelling. Afinitor may cause mental and mood changes, but these are rare.
The most serious side effects of Afinitor include high blood sugar, high cholesterol, high triglycerides, liver problems, kidney problems, kidney failure, lung problems (pneumonitis), and low white blood cell counts, putting the patient at risk for potentially severe infections.
Allergic reactions are rare, but could be severe, and include anaphylaxis, a dangerous drop in blood pressure. Watch for signs of an allergic reaction, such as swelling, rash, or trouble breathing, and seek medical help if you suspect you're having an allergic reaction to Afinitor.
This is not a complete list of possible side effects. Consult with your prescribing doctor or pharmacist about possible side effects and full prescribing information before starting on Afinitor.
Kristi C. Torres, Pharm.D., is a 2005 graduate of The University of Texas at Austin. Her professional background includes academic teaching roles, district-level management for a nationwide pharmacy chain, and clinic-based pharmacy management. Dr. Torres has a wide range of experience in pharmacy operations and has traveled to many states to open and convert clinic-based pharmacies for one of the largest healthcare systems in the nation.
Currently, she works for Tarrytown Expocare Pharmacy in Austin, Texas, serving the intellectual and developmental disability community. There, she leads the order entry team, overseeing orders from across the country.
Dr. Torres began working in pharmacy at the age of 16 in a small East Texas town. She currently resides in Round Rock, Texas, with her daughter and a Shih-Tzu puppy.
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SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2026 SingleCare Administrators. All rights reserved