What is Aliskiren: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Aliskiren overview

BRAND NAMES:

  • Tekturna

Generic Names:

  • Aliskiren Fumarate

Uses:

  • Treats high blood pressure.

Therapeutic Classes:

  • Antihypertensive

Forms:

  • Pellet, Tablet

How it’s taken:

  • By mouth

What is Aliskiren used for?

What form(s) does Aliskiren come in

  • Pellet

  • Tablet

What are common Aliskiren doses?

  • Tablet 150MG

  • Tablet 300MG

Common Aliskiren prescriptions

  • Aliskiren Fumarate
    150mg tablet

  • Aliskiren Fumarate
    300mg tablet

How to take Aliskiren

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • Take this medicine the same way and at the same time every day. Take it routinely with or without food. Do not take with a high-fat meal.

  • Pellet: Do not swallow the capsule whole. Empty the contents of a capsule into a spoon. Swallow the pellets right away with milk (dairy or soy-based) or water. You may also mix the pellets with 1 or more teaspoons of vanilla pudding, vanilla ice cream, milk, or water. Do not chew or crush the pellets.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Store the medicine in its original container.

  • Take this medicine the same way and at the same time every day. Take it routinely with or without food. Do not take with a high-fat meal.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Pellet: Do not swallow the capsule whole. Empty the contents of a capsule into a spoon. Swallow the pellets right away with milk (dairy or soy-based) or water. You may also mix the pellets with 1 or more teaspoons of vanilla pudding, vanilla ice cream, milk, or water. Do not chew or crush the pellets.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Store the medicine in its original container.

What to do if you miss a dose of Aliskiren

Aliskiren contraindications

  • This medicine is not right for everyone. Do not use if you had an allergic reaction to aliskiren, or if you are pregnant.

Aliskiren warnings

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.

  • Do not breastfeed during treatment with this medicine.

  • Tell your doctor if you have kidney disease, heart or blood vessel disease (including heart failure or a history of a heart attack), or diabetes.

  • This medicine may cause the following problems:Angioedema (severe swelling), including head and neck swellingLow blood pressureKidney problems

  • This medicine could lower your blood pressure too much when you first use it or if you are dehydrated. Stand or sit up slowly if you feel lightheaded or dizzy.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Aliskiren interactions

  • Do not use this medicine if you have diabetes and are also taking another blood pressure medicine (ACE inhibitor or ARB). Do not use this medicine together with cyclosporine or itraconazole.

  • Some foods and medicines can affect how aliskiren works. Tell your doctor if you are also using any of the following:Diuretic (water pill, including furosemide)NSAIDs (including aspirin, celecoxib, diclofenac, ibuprofen, naproxen)

  • Ask your doctor before you use any medicine, supplement, or salt substitute that contains potassium.

  • This medicine could lower your blood pressure too much when you first use it or if you are dehydrated. Stand or sit up slowly if you feel lightheaded or dizzy.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Aliskiren side effects

Serious Side Effects

  • Rapid weight gain, swelling in your hands, ankles, or feet

  • Confusion, weakness, uneven heartbeat, trouble breathing, numbness or tingling in your hands, feet, or lips

  • Lightheadedness, dizziness, or fainting

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Decrease in how much or how often you urinate

Less Serious Side Effects

  • Diarrhea

Subscribe to our savings newsletter

Health education, drug info, wellness & more

By clicking 'Subscribe', I agree to SingleCare's Terms & Conditions.